Physiological Insights from Cellular and Network Models of the Stomatogastric Nervous System of Lobsters and Crabs

Synopsis. The stomatogastric nervous system of decapod crustaceans is an ideal system for the study of the processes underlying the generation of rhythmic movements by the nervous system. In this chapter we review recent work that uses mathematical analyses and computer simulations to understand: 1) the role of individual currents in controlling the activity of neurons, and 2) the effects of electrical coupling on the activity of neuronal oscillators. The aim of this review is to highlight, for the physiologist, what these studies have taught us about the organization and function of single cell and multicellular neuronal oscillators.

[1]  R. Harris-Warrick,et al.  Multiple mechanisms of bursting in a conditional bursting neuron , 1987, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[2]  E Marder,et al.  A modulatory proctolin-containing neuron (MPN). I. Identification and characterization , 1989, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[3]  E Marder,et al.  Modulation of the lobster pyloric rhythm by the peptide proctolin , 1987, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[4]  C. Stevens,et al.  Voltage clamp studies of a transient outward membrane current in gastropod neural somata , 1971, The Journal of physiology.

[5]  R. Harris-Warrick,et al.  Modulation of neural networks for behavior. , 1991, Annual review of neuroscience.

[6]  E. Marder,et al.  Transmitter identification of pyloric neurons: electrically coupled neurons use different transmitters. , 1984, Journal of neurophysiology.

[7]  E. Marder,et al.  Contribution of individual ionic currents to activity of a model stomatogastric ganglion neuron. , 1992, Journal of neurophysiology.

[8]  R. Harris-Warrick,et al.  Aminergic modulation in lobster stomatogastric ganglion. II. Target neurons of dopamine, octopamine, and serotonin within the pyloric circuit. , 1986, Journal of neurophysiology.

[9]  E. Marder,et al.  The effect of electrical coupling on the frequency of model neuronal oscillators. , 1990, Science.

[10]  E. Marder,et al.  Electrically coupled pacemaker neurons respond differently to same physiological inputs and neurotransmitters. , 1984, Journal of neurophysiology.

[11]  Eve Marder,et al.  Modification of Oscillator Function by Electrical Coupling to Nonoscillatory Neurons , 1992 .

[12]  Eve Marder,et al.  Order Reduction for Dynamical Systems Describing the Behavior of Complex Neurons , 1990, NIPS.

[13]  Eve Marder,et al.  Oscillating Networks: Control of Burst Duration by Electrically Coupled Neurons , 1991, Neural Computation.

[14]  E. Marder,et al.  A mechanism for production of phase shifts in a pattern generator. , 1984, Journal of neurophysiology.

[15]  E. Marder,et al.  Mathematical model of an identified stomatogastric ganglion neuron. , 1992, Journal of neurophysiology.

[16]  R. FitzHugh Impulses and Physiological States in Theoretical Models of Nerve Membrane. , 1961, Biophysical journal.

[17]  E. Marder,et al.  A NEURONAL ROLE FOR A CRUSTACEAN RED PIGMENT CONCENTRATING HORMONE-LIKE PEPTIDE: NEUROMODULATION OF THE PYLORIC RHYTHM IN THE CRAB, CANCER BOREALIS , 1988 .

[18]  J. Connor,et al.  Neural repetitive firing: modifications of the Hodgkin-Huxley axon suggested by experimental results from crustacean axons. , 1977, Biophysical journal.

[19]  E Marder,et al.  A modulatory proctolin-containing neuron (MPN). II. State-dependent modulation of rhythmic motor activity , 1989, The Journal of neuroscience : the official journal of the Society for Neuroscience.