Variations of DNA-(cytosine-5-)-methyltransferase activities after administration of N-hydroxy-N-aminofluorene to Sprague-Dawley rats.

[1]  J. Noshari,et al.  Subunit and functional size of human placental DNA methyltransferase involved in de novo and maintenance methylation. , 1987, The Journal of biological chemistry.

[2]  J. Miller,et al.  Initiation of hepatocarcinogenesis in infant male B6C3F1 mice by N-hydroxy-2-aminofluorene or N-hydroxy-2-acetylaminofluorene depends primarily on metabolism to N-sulfooxy-2-aminofluorene and formation of DNA-(deoxyguanosin-8-yl)-2-aminofluorene adducts. , 1987, Carcinogenesis.

[3]  G. Dirheimer,et al.  Changes in de novo DNA (cytosine-5-)-methyltransferase activity in oncogenically susceptible rat target tissues induced by N-methyl-N-nitrosourea. , 1986, Cancer research.

[4]  P. Jones,et al.  DNA methyltransferase levels in tumorigenic and nontumorigenic cells in culture. , 1986, The Journal of biological chemistry.

[5]  G. Pfeifer,et al.  Purification and characterization of mammalian DNA methyltransferases by use of monoclonal antibodies. , 1985, The Journal of biological chemistry.

[6]  S. Thorgeirsson,et al.  Association between DNA strand breaks and specific DNA adducts in murine hepatocytes following in vivo and in vitro exposure to N-hydroxy-2-acetylaminofluorene and N-acetoxy-2-acetylaminofluorene. , 1985, Carcinogenesis.

[7]  G. Pfeifer,et al.  Characterization of DNA methylating enzymes by use of monoclonal antibodies. , 1985, Progress in clinical and biological research.

[8]  R. Fuchs,et al.  In vitro enzymatic methylation of DNA substituted by N‐2‐aminofluorene , 1984, FEBS letters.

[9]  J. F. Young,et al.  DNA adduct formation, removal and persistence in rat liver during one month of feeding 2-acetylaminofluorene. , 1984, Carcinogenesis.

[10]  J. Siedlecki,et al.  DNA methylation. Inhibition of de novo and maintenance methylation in vitro by RNA and synthetic polynucleotides. , 1984, The Journal of biological chemistry.

[11]  M. Graichen,et al.  Elevation of hepatic microsomal epoxide hydrolase activity by 2-acetylaminofluorene: strain and species differences , 1984, Carcinogenesis.

[12]  Christman Jk.  DNA methylation in friend erythroleukemia cells: the effects of chemically induced differentiation and of treatment with inhibitors of DNA methylation. , 1984 .

[13]  D. Drahovsky,et al.  DNA-cytosine-5-methyltransferase from P815 mouse mastocytoma cells: "maintenance" and "de novo" activities are carried out by the same enzyme molecule. , 1984, The International journal of biochemistry.

[14]  R. Hoffman,et al.  Altered methionine metabolism, DNA methylation and oncogene expression in carcinogenesis. A review and synthesis. , 1984, Biochimica et biophysica acta.

[15]  S. Galiègue‐Zouitina,et al.  Enzymatic methylation of DNA and poly(dG—dC) · poly(dG—dC) modified by 4‐acetoxyaminoquinoline‐1‐oxide, the ultimate carcinogen of 4‐nitroquinoline‐1‐oxide , 1983, FEBS letters.

[16]  G. Keith,et al.  Enzymatic methylation of chemically alkylated DNA and poly(dG-dC) X poly(dG-dC) in B and Z forms. , 1983, Biochemical and biophysical research communications.

[17]  Peter A. Jones,et al.  Inhibition of DNA methylation by chemical carcinogens in vitro , 1983, Cell.

[18]  G. Dirheimer,et al.  Comparison of different methods of recovering DNA from a methylation assay. , 1982, Biochimie.

[19]  F. Beland,et al.  Persistence of DNA adducts in rat liver and kidney after multiple doses of the carcinogen N-hydroxy-2-acetylaminofluorene. , 1982, Cancer research.

[20]  R. Fuchs,et al.  Inhibitory model of methylation in carcinogen modified DNA , 1982 .

[21]  R. Fuchs,et al.  Mechanism of inhibition of enzymatic deoxyribonucleic acid methylation by 2-(acetylamino)fluorene bound to deoxyribonucleic acid. , 1981, Biochemistry.

[22]  Becker Ff,et al.  DNA methylase activity of normal liver, regenerating liver, and a transplantable hepatocellular carcinoma. , 1981 .

[23]  F. Becker,et al.  DNA methylation and methylase levels in normal and malignant mouse hepatic tissues. , 1981, Carcinogenesis.

[24]  C. Salas,et al.  Effect of modification by N-acetoxy-N-2-acetylaminofluorene on the level of DNA methylation , 1979, Nature.

[25]  J. Lefèvre,et al.  Comparative studies on the 7-iodo and 7-fluoro derivatives of N-acetoxy-N-2-acetylaminofluorene: binding sites on DNA and conformational change of modified deoxytrinucleotides. , 1978, Biochemistry.

[26]  J. Westra,et al.  Identification of the persistently bound form of the carcinogen N-acetyl-2-aminofluorene to rat liver DNA in vivo. , 1976, Chemico-biological interactions.

[27]  C. Irving.  Comparative toxicity of N-hydroxy-2-acetylaminofluorene in several strains of rats. , 1975, Cancer research.

[28]  E. Kriek.  Persistent binding of a new reaction product of the carcinogen N-hydroxy-N-2-acetylaminofluorene with guanine in rat liver DNA in vivo. , 1972, Cancer research.

[29]  R. Rydell,et al.  On the correlation between the hepatocarcinogenicity of the carcinogen, N-2-fluorenylacetamide, and its metabolic activation by the rat. , 1972, Cancer research.

[30]  J. Miller,et al.  N-hydroxy-2-acetylaminofluorene sulfotransferase: its probable role in carcinogenesis and in protein-(methion-S-yl) binding in rat liver. , 1970, Cancer research.

[31]  E. Kriek,et al.  On the mechanism of action of carcinogenic aromatic amines. I. Binding of 2-acetylaminofluorene and N-hydroxy-2-acetylaminofluorene to rat-liver nucleic acids in vivo. , 1969, Chemico-biological interactions.

[32]  C. Irving,et al.  Persistent binding of 2-acetylaminofluorene to rat liver DNA in vivo and consideration of the mechanism of binding of N-hydroxy-2-acetylaminofluorene to rat liver nucleic acids. , 1969, Cancer research.

[33]  J. Miller,et al.  THE COMPARATIVE CARCINOGENICITIES OF 2-ACETYLAMINOFLUORENE AND ITS N-HYDROXY METABOLITE IN MICE, HAMSTERS, AND GUINEA PIGS. , 1964, Cancer research.

[34]  J. Miller,et al.  N-Hydroxy-2-acetylaminofluorene: a metabolite of 2-acetylaminofluorene with increased carcinogenic activity in the rat. , 1961, Cancer research.