Selective thyroid hormone receptor-β activation: A strategy for reduction of weight, cholesterol, and lipoprotein (a) with reduced cardiovascular liability
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Johan Malm | Liu Ye | Mark A. Smith | J. Baxter | L. Ye | Yi-lin Li | K. Mellström | L. Bladh | G. Grover | P. Sleph | R. George | J. Malm | K. Mookhtiar | Mark A Smith | John D Baxter | B. Vennström | Karin Mellström | R. Horvath | Gary J Grover | Yi-Lin Li | Lars-Göran Bladh | Paul G Sleph | Rocco George | Björn Vennström | Kasim Mookhtiar | Ryan Horvath | Jessica Speelman | Donald Egan | Donald M Egan | Jessica S Speelman | Ryan J. Horvath
[1] H. Ditschuneit,et al. Treatment of type II hyperlipoproteinemia with d-thyroxine. , 1976, Atherosclerosis.
[2] L. Ye,et al. Thyroid receptor ligands. 1. Agonist ligands selective for the thyroid receptor beta1. , 2003, Journal of medicinal chemistry.
[3] R. Fletterick,et al. Structure-based design and synthesis of a thyroid hormone receptor (TR) antagonist. , 2002, Endocrinology.
[4] Frank Baas,et al. Abnormal heart rate and body temperature in mice lacking thyroid hormone receptor α1 , 1998, The EMBO journal.
[5] C. Lim,et al. The thyroid hormone analogue SKF-94901 and iodothyronine binding sites in mammalian tissues: differences in cytoplasmic binding between liver and heart. , 1991, Acta endocrinologica.
[6] A. Catapano,et al. Experimental hypothyroidism modulates the expression of the low density lipoprotein receptor by the liver. , 1986, Atherosclerosis.
[7] T. D. de Bruin,et al. Lipoprotein(a) and apolipoprotein B plasma concentrations in hypothyroid, euthyroid, and hyperthyroid subjects. , 1993, The Journal of clinical endocrinology and metabolism.
[8] I. Klein,et al. Thyroid hormone and the cardiovascular system. , 2001, Minerva endocrinologica.
[9] J. Simons,et al. High level expression of functional full length human thyroid hormone receptor β1 in insect cells using a recombinant baculovirus , 1991, The Journal of Steroid Biochemistry and Molecular Biology.
[10] J. Gustafsson,et al. Differential response of estrogen receptor alpha and estrogen receptor beta to partial estrogen agonists/antagonists. , 1998, Molecular pharmacology.
[11] W. Riesen,et al. Effect of thyroid function on concentrations of lipoprotein(a) , 1993, Clinical chemistry.
[12] S. Shahrara,et al. Thyroid hormone α1 and β1 receptor mRNA are downregulated by amiodarone in mouse myocardium , 1999 .
[13] N. Ling,et al. Quantitation of rat tissue thyroid hormone binding receptor isoforms by immunoprecipitation of nuclear triiodothyronine binding capacity. , 1992, The Journal of biological chemistry.
[14] W. Giles,et al. Cardiac Ion Channel Expression and Contractile Function in Mice with Deletion of Thyroid Hormone Receptor α or β1 , 2001 .
[15] P. Yen,et al. Physiological and molecular basis of thyroid hormone action. , 2001, Physiological reviews.
[16] G. Brent,et al. Thyroid hormone–sympathetic interaction and adaptive thermogenesis are thyroid hormone receptor isoform–specific , 2001 .
[17] B. Cullen,et al. Secreted placental alkaline phosphatase: a powerful new quantitative indicator of gene expression in eukaryotic cells. , 1988, Gene.
[18] J. Oppenheimer,et al. Functional relationship of thyroid hormone-induced lipogenesis, lipolysis, and thermogenesis in the rat. , 1991, The Journal of clinical investigation.
[19] J. C. Emmett,et al. A thyromimetic that decreases plasma cholesterol levels without increasing cardiac activity , 1986, Nature.
[20] B. Gloss,et al. The Thyroid Hormone Receptor-β-Selective Agonist GC-1 Differentially Affects Plasma Lipids and Cardiac Activity. , 2000, Endocrinology.
[21] R. Weiss,et al. The syndromes of resistance to thyroid hormone. , 1993, Endocrine reviews.
[22] T. Hintze,et al. Demonstration of potent lipid-lowering activity by a thyromimetic agent devoid of cardiovascular and thermogenic effects. , 1996, Atherosclerosis.
[23] J. Danesh,et al. Lipoprotein(a) and Coronary Heart Disease: Meta-Analysis of Prospective Studies , 2000, Circulation.
[24] C. Erem,et al. Plasma lipoprotein (a) concentrations in hypothyroid, euthyroid and hyperthyroid subjects. , 1999, Acta cardiologica.
[25] G. Grover,et al. Pharmacologic characterization of BMS-191095, a mitochondrial K(ATP) opener with no peripheral vasodilator or cardiac action potential shortening activity. , 2001, The Journal of pharmacology and experimental therapeutics.
[26] J. Baxter,et al. A high-affinity subtype-selective agonist ligand for the thyroid hormone receptor. , 1998, Chemistry & biology.
[27] D. Forrest,et al. Functions of thyroid hormone receptors in mice. , 2000, Thyroid : official journal of the American Thyroid Association.
[28] S. Iossa,et al. Relationship between the resting metabolic rate and hepatic metabolism in rats: effect of hyperthyroidism and fasting for 24 hours. , 1992, Journal of Endocrinology.
[29] H. Seo,et al. Thyroid hormone action on liver, heart, and energy expenditure in thyroid hormone receptor beta-deficient mice. , 1998, Endocrinology.