Dynamic multivoxel‐localized 31P MRS during plantar flexion exercise with variable knee angle

Exercise studies investigating the metabolic response of calf muscles using 31P MRS are usually performed with a single knee angle. However, during natural movement, the distribution of workload between the main contributors to force, gastrocnemius and soleus is influenced by the knee angle. Hence, it is of interest to measure the respective metabolic response of these muscles to exercise as a function of knee angle using localized spectroscopy.

[1]  Ewald Moser,et al.  Exercising calf muscle changes correlate with pH, PCr recovery and maximum oxidative phosphorylation , 2014, NMR in biomedicine.

[2]  K. Nishikawa.  Eccentric contraction: unraveling mechanisms of force enhancement and energy conservation , 2016, Journal of Experimental Biology.

[3]  G. Goelman,et al.  pH heterogeneity during exercise in localized spectra from single human muscles. , 1993, The American journal of physiology.

[4]  R. B. Moon,et al.  Determination of intracellular pH by 31P magnetic resonance. , 1973, The Journal of biological chemistry.

[5]  G. Matheson,et al.  Simultaneous 31P MRS of the soleus and gastrocnemius in Sherpas during graded calf muscle exercise. , 1997, The American journal of physiology.

[6]  John C Gore,et al.  Comparison of MRI with EMG to study muscle activity associated with dynamic plantar flexion. , 2003, Magnetic resonance imaging.

[7]  D. I. Hoult,et al.  Observation of tissue metabolites using 31P nuclear magnetic resonance , 1974, Nature.

[8]  Ewald Moser,et al.  Localized semi-LASER dynamic 31P magnetic resonance spectroscopy of the soleus during and following exercise at 7 T , 2015, Magnetic Resonance Materials in Physics, Biology and Medicine.

[9]  Vanhamme,et al.  Improved method for accurate and efficient quantification of MRS data with use of prior knowledge , 1997, Journal of magnetic resonance.

[10]  G. Radda,et al.  The production, buffering and efflux of protons in human skeletal muscle during exercise and recovery , 1993, NMR in biomedicine.

[11]  Wolfgang Bogner,et al.  Dynamic 31P–MRSI using spiral spectroscopic imaging can map mitochondrial capacity in muscles of the human calf during plantar flexion exercise at 7 T , 2016, NMR in biomedicine.

[12]  D. Manners,et al.  Effects of exercise‐induced intracellular acidosis on the phosphocreatine recovery kinetics: a 31P MRS study in three muscle groups in humans , 2013, NMR in biomedicine.

[13]  Arend Heerschap,et al.  Towards 1H-MRSI of the human brain at 7T with slice-selective adiabatic refocusing pulses , 2008, Magnetic Resonance Materials in Physics, Biology and Medicine.

[14]  D. Graveron-Demilly,et al.  Java-based graphical user interface for the MRUI quantitation package , 2001, Magnetic Resonance Materials in Physics, Biology and Medicine.

[15]  Ewald Moser,et al.  Interleaved multivoxel 31P MR spectroscopy , 2016, Magnetic resonance in medicine.

[16]  G J Kemp,et al.  Quantification of skeletal muscle mitochondrial function by 31P magnetic resonance spectroscopy techniques: a quantitative review , 2015, Acta physiologica.

[17]  Wolfgang Bogner,et al.  Depth‐resolved surface coil MRS (DRESS)‐localized dynamic 31P‐MRS of the exercising human gastrocnemius muscle at 7 T , 2014, NMR in biomedicine.

[18]  Ewald Moser,et al.  Comparing localized and nonlocalized dynamic 31P magnetic resonance spectroscopy in exercising muscle at 7T , 2012, Magnetic resonance in medicine.

[19]  Philip D. Gollnick,et al.  Human soleus muscle: A comparison of fiber composition and enzyme activities with other leg muscles , 1974, Pflügers Archiv.

[20]  Li Feng,et al.  Rapid 3D‐imaging of phosphocreatine recovery kinetics in the human lower leg muscles with compressed sensing , 2012, Magnetic resonance in medicine.

[21]  Ewald Moser,et al.  Absolute quantification of phosphorus metabolite concentrations in human muscle in vivo by 31P MRS: a quantitative review , 2007, NMR in biomedicine.

[22]  Ewald Moser,et al.  Semi-LASER localized dynamic 31P magnetic resonance spectroscopy in exercising muscle at ultra-high magnetic field , 2011, Magnetic resonance in medicine.

[23]  E. Moser,et al.  Dynamic interleaved 1H/31P STEAM MRS at 3 Tesla using a pneumatic force-controlled plantar flexion exercise rig , 2005, Magnetic Resonance Materials in Physics, Biology and Medicine.

[24]  A. McComas,et al.  Influence of joint position on ankle plantarflexion in humans. , 1982, Journal of applied physiology: respiratory, environmental and exercise physiology.

[25]  W. Herzog,et al.  Energy cost of isometric force production after active shortening in skinned muscle fibres , 2017, Journal of Experimental Biology.

[26]  Shoko Nioka,et al.  Skeletal muscle energetics with PNMR: personal views and historic perspectives , 2006, NMR in biomedicine.

[27]  Ewald Moser,et al.  Skeletal muscle ATP synthesis and cellular H+ handling measured by localized 31P-MRS during exercise and recovery , 2016, Scientific Reports.

[28]  M. Johnson,et al.  Data on the distribution of fibre types in thirty-six human muscles. An autopsy study. , 1973, Journal of the neurological sciences.

[29]  Ravinder R Regatte,et al.  Dynamic three‐dimensional imaging of phosphocreatine recovery kinetics in the human lower leg muscles at 3T and 7T: a preliminary study , 2013, NMR in biomedicine.

[30]  C. Hughes.  Kinesiology: The Mechanics and Pathomechanics of Human Movement , 2004 .

[31]  S. Forbes,et al.  Comparison of oxidative capacity among leg muscles in humans using gated 31P 2‐D chemical shift imaging , 2009, NMR in biomedicine.

[32]  Ewald Moser,et al.  A form‐fitted three channel 31P, two channel 1H transceiver coil array for calf muscle studies at 7 T , 2015, Magnetic resonance in medicine.