The S2 subsites of cathepsins K and L and their contribution to collagen degradation
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E. Purisima | D. Brömme | Dieter Brömme | Gilles Lalmanach | Fabien Lecaille | Shafinaz Chowdhury | Enrico Purisima | G. Lalmanach | F. Lecaille | S. Chowdhury
[1] J G Gleason,et al. Design of potent and selective human cathepsin K inhibitors that span the active site. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[2] J. Kopeček,et al. Inhibition of cathepsin K with lysosomotropic macromolecular inhibitors. , 2002, Biochemistry.
[3] Enrico O. Purisima,et al. A simple yet accurate boundary element method for continuum dielectric calculations , 1995, J. Comput. Chem..
[4] Imran Siddiqi,et al. Solvated Interaction Energy (SIE) for Scoring Protein-Ligand Binding Affinities, 1. Exploring the Parameter Space , 2007, J. Chem. Inf. Model..
[5] F. Costa,et al. A polymorphism in the angiogenesis inhibitor, endostatin, in multiple myeloma. , 2003, Leukemia research.
[6] D. Brömme,et al. Thiol-dependent cathepsins: pathophysiological implications and recent advances in inhibitor design. , 2002, Current pharmaceutical design.
[7] A. Hollander,et al. Molecular Interaction and Matrix Assembly , 1998, The Biochemical journal.
[8] D. Turk,et al. Lysosomal cysteine proteases: facts and opportunities , 2001, The EMBO journal.
[9] H. Kawashima,et al. Substrate specificity of recombinant osteoclast-specific cathepsin K from rabbits. , 1996, Biological & pharmaceutical bulletin.
[10] M. Bogyo,et al. Regulation of Collagenase Activities of Human Cathepsins by Glycosaminoglycans* , 2004, Journal of Biological Chemistry.
[11] Enrico O. Purisima,et al. Fast summation boundary element method for calculating solvation free energies of macromolecules , 1998 .
[12] D. Brömme,et al. Collagenolytic activity of cathepsin K is specifically modulated by cartilage-resident chondroitin sulfates. , 2000, Biochemistry.
[13] B. Gelb,et al. Collagenase Activity of Cathepsin K Depends on Complex Formation with Chondroitin Sulfate* , 2002, The Journal of Biological Chemistry.
[14] J F Morrison,et al. The kinetics of reversible tight-binding inhibition. , 1979, Methods in enzymology.
[15] J. Whisstock,et al. For the record: A single amino acid substitution affects substrate specificity in cysteine proteinases from Fasciola hepatica , 2000, Protein science : a publication of the Protein Society.
[16] E. Purisima,et al. Design of noncovalent inhibitors of human cathepsin L. From the 96-residue proregion to optimized tripeptides. , 2002, Journal of medicinal chemistry.
[17] Enrico O. Purisima,et al. Fast summation boundary element method for calculating solvation free energies of macromolecules , 1998, J. Comput. Chem..
[18] J. Deussing,et al. Cathepsin L deficiency as molecular defect of furless: hyperproliferation of keratinocytes and pertubation of hair follicle cycling , 2000, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[19] J. Richardson,et al. Asparagine and glutamine: using hydrogen atom contacts in the choice of side-chain amide orientation. , 1999, Journal of molecular biology.
[20] C. Craik,et al. Selective inhibition of the collagenolytic activity of human cathepsin K by altering its S2 subsite specificity. , 2002, Biochemistry.
[21] Matthew Bogyo,et al. Cathepsin V, a Novel and Potent Elastolytic Activity Expressed in Activated Macrophages* , 2004, Journal of Biological Chemistry.
[22] P. Kollman,et al. A Second Generation Force Field for the Simulation of Proteins, Nucleic Acids, and Organic Molecules , 1995 .
[23] L. Juliano,et al. A possible alternative mechanism of kinin generation in vivo by cathepsin L , 2005, Biological chemistry.
[24] H. Chapman,et al. Protease injury in the development of COPD: Thomas A. Neff Lecture. , 2000, Chest.
[25] J. Palmer,et al. Localization of Rat Cathepsin K in Osteoclasts and Resorption Pits: Inhibition of Bone Resorption and Cathepsin K-Activity by Peptidyl Vinyl Sulfones , 1999, Biological chemistry.
[26] V. Herzog,et al. Cathepsin K in thyroid epithelial cells: sequence, localization and possible function in extracellular proteolysis of thyroglobulin. , 2000, Journal of cell science.
[27] Jean-Daniel Zucker,et al. Cathepsin S, a novel biomarker of adiposity: relevance to atherogenesis , 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[28] Francesco Leonetti,et al. Substrate Profiling of Cysteine Proteases Using a Combinatorial Peptide Library Identifies Functionally Unique Specificities* , 2006, Journal of Biological Chemistry.
[29] D. Brömme,et al. Human and parasitic papain-like cysteine proteases: their role in physiology and pathology and recent developments in inhibitor design. , 2002, Chemical reviews.
[30] R. Ménard,et al. Family C1 Cysteine Proteases: Biological Diversity or Redundancy? , 2003, Biological chemistry.
[31] J. Morrison,et al. [17] The kinetics of reversible tight-binding inhibition , 1979 .
[32] D J Prockop,et al. Collagens: molecular biology, diseases, and potentials for therapy. , 1995, Annual review of biochemistry.
[33] P. Delmas,et al. The Collagenolytic Activity of Cathepsin K Is Unique among Mammalian Proteinases* , 1998, The Journal of Biological Chemistry.
[34] H. Scheraga,et al. Monte Carlo-minimization approach to the multiple-minima problem in protein folding. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[35] D. Brömme,et al. Modulation of hypotensive effects of kinins by cathepsin K. , 2007, Archives of biochemistry and biophysics.
[36] A. Barrett,et al. L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L. , 1982, The Biochemical journal.
[37] D. Hanahan,et al. Multiple Roles for Cysteine Cathepsins in Cancer , 2004, Cell cycle.
[38] H. Chapman,et al. Cathepsins and compartmentalization in antigen presentation. , 2000, Current opinion in immunology.
[39] T. Welte,et al. Pivotal role of cathepsin K in lung fibrosis. , 2004, The American journal of pathology.
[40] A. Barrett,et al. Inhibition of cysteine proteinases and dipeptidyl peptidase I by egg-white cystatin. , 1984, The Biochemical journal.
[41] J. Palmer,et al. Peptidyl vinyl sulphones: a new class of potent and selective cysteine protease inhibitors: S2P2 specificity of human cathepsin O2 in comparison with cathepsins S and L. , 1996, The Biochemical journal.
[42] H. Chapman,et al. Emerging roles for cysteine proteases in human biology. , 1997, Annual review of physiology.
[43] M. Bogyo,et al. Cathepsin L in secretory vesicles functions as a prohormone-processing enzyme for production of the enkephalin peptide neurotransmitter , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[44] P. Saftig,et al. Cathepsin K: a cysteine protease with unique kinin-degrading properties. , 2004, The Biochemical journal.