ZNRF3 Regulates Collagen-Induced Arthritis Through NF-kB and Wnt Pathways

[1]  Y. Kato,et al.  Immunohistochemical Analysis of the Harbor Porpoise Using Antipodoplanin Antibody PMab-237. , 2019, Monoclonal antibodies in immunodiagnosis and immunotherapy.

[2]  H. Li,et al.  Diallyl Trisulfide can induce fibroblast-like synovial apoptosis and has a therapeutic effect on collagen-induced arthritis in mice via blocking NF-κB and Wnt pathways. , 2019, International immunopharmacology.

[3]  Y. Liu,et al.  SIRT1 inhibits rheumatoid arthritis fibroblast-like synoviocyte aggressiveness and inflammatory response via suppressing NF-κB pathway , 2018, Bioscience reports.

[4]  S. Serra,et al.  Rnf43 , 2017, Journal of Clinical Pathology.

[5]  M. Guma,et al.  Fibroblast-like synoviocyte metabolism in the pathogenesis of rheumatoid arthritis , 2017, Arthritis Research & Therapy.

[6]  Wei Xu,et al.  Dishevelled2 promotes apoptosis and inhibits inflammatory cytokine secretion in rheumatoid arthritis fibroblast-like synoviocytes through crosstalk with the NF-κB pathway , 2017, Oncotarget.

[7]  M. Hottiger,et al.  Crosstalk between Wnt/β-Catenin and NF-κB Signaling Pathway during Inflammation , 2016, Front. Immunol..

[8]  Qin Wang,et al.  Mesenchymal stem cells alleviate experimental rheumatoid arthritis through microRNA-regulated IκB expression , 2016, Scientific Reports.

[9]  Xiaomo Jiang,et al.  Control of Wnt Receptor Turnover by R-spondin-ZNRF3/RNF43 Signaling Module and Its Dysregulation in Cancer , 2016, Cancers.

[10]  Yunxia Li,et al.  Interleukin-35 attenuates collagen-induced arthritis through suppression of vascular endothelial growth factor and its receptors. , 2016, International immunopharmacology.

[11]  J. Campbell,et al.  Preclinical characterisation of the GM-CSF receptor as a therapeutic target in rheumatoid arthritis , 2014, Annals of the rheumatic diseases.

[12]  Yang Xu,et al.  Structural and molecular basis of ZNRF3/RNF43 transmembrane ubiquitin ligase inhibition by the Wnt agonist R-spondin , 2013, Nature Communications.

[13]  Y. Huang,et al.  Wnt signaling pathway in rheumatoid arthritis, with special emphasis on the different roles in synovial inflammation and bone remodeling. , 2013, Cellular signalling.

[14]  D. Cai,et al.  Fractalkine stimulates cell growth and increases its expression via NF‐κB pathway in RA‐FLS , 2012, International journal of rheumatic diseases.

[15]  H. Ruffner,et al.  ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner , 2012, Nature.

[16]  A. Kinloch,et al.  Citrullination of autoantigens: Upstream of TNFα in the pathogenesis of rheumatoid arthritis , 2011, FEBS letters.

[17]  J. Gottenberg,et al.  Synovial fibroblasts promote immunoglobulin class switching by a mechanism involving BAFF , 2011, European journal of immunology.

[18]  J. Gu,et al.  Expression of β-catenin in rheumatoid arthritis fibroblast-like synoviocytes , 2011, Scandinavian journal of rheumatology.

[19]  A. Silman,et al.  UvA-DARE (Digital Academic Repository) 2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative Aletaha, , 2010 .

[20]  A. Silman,et al.  Rheumatoid arthritis classifi cation criteria : an American College of Rheumatology / European League Against Rheumatism collaborative initiative , 2010 .

[21]  Georg Schett,et al.  Cytokines in the pathogenesis of rheumatoid arthritis , 2007, Nature Reviews Immunology.

[22]  Z. Zhan,et al.  Anti-malarial agent artesunate inhibits TNF-alpha-induced production of proinflammatory cytokines via inhibition of NF-kappaB and PI3 kinase/Akt signal pathway in human rheumatoid arthritis fibroblast-like synoviocytes. , 2007, Rheumatology.

[23]  D. Brand,et al.  Collagen-induced arthritis , 2007, Nature Protocols.

[24]  Cun-Yu Wang,et al.  IKKα stabilizes cytosolic β-catenin by inhibiting both canonical and non-canonical degradation pathways , 2006 .

[25]  Emilio Hirsch,et al.  Blockade of PI3Kγ suppresses joint inflammation and damage in mouse models of rheumatoid arthritis , 2005, Nature Medicine.

[26]  M. Sen,et al.  Wnt signalling in rheumatoid arthritis. , 2005, Rheumatology.

[27]  S. Gay,et al.  Apoptosis in rheumatoid arthritis , 2003, Current opinion in rheumatology.

[28]  R. Gaynor,et al.  IKKalpha regulates mitogenic signaling through transcriptional induction of cyclin D1 via Tcf. , 2003, Molecular biology of the cell.

[29]  R. Gaynor,et al.  Regulation of β-Catenin Function by the IκB Kinases* , 2001, The Journal of Biological Chemistry.

[30]  G. Firestein,et al.  Expression and function of wingless and frizzled homologs in rheumatoid arthritis. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[31]  J. Kriegsmann,et al.  Synovial fibroblasts of patients with rheumatoid arthritis attach to and invade normal human cartilage when engrafted into SCID mice. , 1996, The American journal of pathology.

[32]  G. Firestein.  Invasive fibroblast-like synoviocytes in rheumatoid arthritis. Passive responders or transformed aggressors? , 1996, Arthritis and rheumatism.

[33]  Cun-Yu Wang,et al.  IKKalpha stabilizes cytosolic beta-catenin by inhibiting both canonical and non-canonical degradation pathways. , 2006, Cellular signalling.

[34]  R. Gaynor,et al.  Regulation of beta-catenin function by the IkappaB kinases. , 2001, The Journal of biological chemistry.