Perspectives for mass spectrometry and functional proteomics.
暂无分享,去创建一个
[1] A. Tomlinson,et al. One step microelectroelution concentration method for efficient coupling of sodium dodecylsulfate gel electrophoresis and matrix-assisted laser desorption time-of-flight mass spectrometry for protein analysis , 1998, Journal of the American Society for Mass Spectrometry.
[2] P. Benjamin,et al. Matrix‐assisted laser desorption/ionization time of flight mass spectrometric analysis of the pattern of peptide expression in single neurons resulting from alternative mRNA splicing of the FMRFamide gene , 1998, The European journal of neuroscience.
[3] W. Chen,et al. Proteome analysis of factor for inversion stimulation (Fis) overproduction in Escherichia coli. , 2007, Electrophoresis.
[4] M. Karas,et al. Performance of Infrared Matrix-assisted Laser Desorption/Ionization Mass Spectrometry with Lasers Emitting in the 3 μm Wavelength Range , 1997 .
[5] S. Aparicio,et al. How to count…human genes , 2000, Nature Genetics.
[6] James I. Garrels,et al. The Yeast Proteome Database (YPD): a model for the organization and presentation of genome-wide functional data , 1999, Nucleic Acids Res..
[7] G. Anderson,et al. In-trap cleanup of proteins from electrospray ionization using soft sustained off-resonance irradiation with fourier transform ion cyclotron resonance mass spectrometry. , 1998, Analytical chemistry.
[8] R. Crouch,et al. Palmitylation of a G-protein coupled receptor. Direct analysis by tandem mass spectrometry. , 1992, The Journal of biological chemistry.
[9] Rolf Apweiler,et al. The SWISS-PROT protein sequence database and its supplement TrEMBL in 2000 , 2000, Nucleic Acids Res..
[10] Angelika Görg,et al. Comparison of yeast cell protein solubilization procedures for two‐dimensional electrophoresis , 1999, Electrophoresis.
[11] A. Levine. p53, the Cellular Gatekeeper for Growth and Division , 1997, Cell.
[12] P. Bohley,et al. Chapter 6 Intracellular proteolysis , 1987 .
[13] B. Futcher,et al. A Sampling of the Yeast Proteome , 1999, Molecular and Cellular Biology.
[14] Y. Ioannou,et al. Ribosomal proteins in cell proliferation and apoptosis. , 1999, International reviews of immunology.
[15] Veeranna,et al. Characterization of serine and threonine phosphorylation sites in beta-elimination/ethanethiol addition-modified proteins by electrospray tandem mass spectrometry and database searching. , 1998, Biochemistry.
[16] B. Chait,et al. The Yeast Nuclear Pore Complex: Composition, Architecture, and Transport Mechanism , 2000 .
[17] J. Claverie. Computational methods for the identification of genes in vertebrate genomic sequences. , 1997, Human molecular genetics.
[18] Masaru Tomita,et al. E-CELL: software environment for whole-cell simulation , 1999, Bioinform..
[19] A. Shevchenko,et al. Rapid 'de novo' peptide sequencing by a combination of nanoelectrospray, isotopic labeling and a quadrupole/time-of-flight mass spectrometer. , 1997, Rapid communications in mass spectrometry : RCM.
[20] M S Boguski,et al. Human and nematode orthologs--lessons from the analysis of 1800 human genes and the proteome of Caenorhabditis elegans. , 1999, Gene.
[21] C. Adessi,et al. Two‐dimensional electrophoresis of membrane proteins: A current challenge for immobilized pH gradients , 1997, Electrophoresis.
[22] H. Lehrach,et al. Analysis of the mouse proteome. (I) Brain proteins: Separation by two‐dimensional electrophoresis and identification by mass spectrometry and genetic variation , 1999, Electrophoresis.
[23] H. Perreault,et al. Use of a non-porous polyurethane membrane as a sample support for matrix-assisted laser desorption/ionization time-of-flight mass spectrometry of peptides and proteins. , 1997, Rapid communications in mass spectrometry : RCM.
[24] Preparing 2-D protein extracts from Caenorhabditis elegans. , 1999, Methods in molecular biology.
[25] J. Gebler,et al. Charge derivatization of peptides to simplify their sequencing with an ion trap mass spectrometer. , 1999, Rapid communications in mass spectrometry : RCM.
[26] P. Højrup,et al. Rapid identification of proteins by peptide-mass fingerprinting , 1993, Current Biology.
[27] C. Gray,et al. Strategies towards a better understanding of antibiotic action: Folate pathway inhibition in Haemophilus influenzae as an example , 1998, Electrophoresis.
[28] J. Seilhamer,et al. A comparison of selected mRNA and protein abundances in human liver , 1997, Electrophoresis.
[29] R. Fleischmann,et al. Whole-genome random sequencing and assembly of Haemophilus influenzae Rd. , 1995, Science.
[30] R. Hammer,et al. Interaction of endothelin-3 with endothelin-B receptor is essential for development of epidermal melanocytes and enteric neurons , 1994, Cell.
[31] Wayne F. Patton,et al. A thousand points of light: The application of fluorescence detection technologies to two‐dimensional gel electrophoresis and proteomics , 2000, Electrophoresis.
[32] C. Fizames,et al. Estimate of human gene number provided by genome-wide analysis using Tetraodon nigroviridis DNA sequence , 2000, Nature Genetics.
[33] R. Aebersold,et al. Analysis of membrane proteins by two‐dimensional electrophoresis: Comparison of the proteins extracted from normal or Plasmodium falciparum ‐ infected erythrocyte ghosts , 1999, Electrophoresis.
[34] C. Gray,et al. Two‐dimensional map of the proteome of Haemophilus influenzae , 2000, Electrophoresis.
[35] M. Kussmann,et al. Comparison of in vivo and in vitro phosphorylation of the exocytosis-sensitive protein PP63/parafusin by differential MALDI mass spectrometric peptide mapping. , 1999, Biochemistry.
[36] J. Claverie. Computational methods for the identification of differential and coordinated gene expression. , 1999, Human molecular genetics.
[37] Donald E. Ingber,et al. The structural and mechanical complexity of cell-growth control , 1999, Nature Cell Biology.
[38] H. Sariola,et al. Hirschsprung's disease genes and the development of the enteric nervous system. , 1998, Annals of medicine.
[39] Z. Zhang,et al. De novo peptide sequencing by two-dimensional fragment correlation mass spectrometry. , 2000, Analytical chemistry.
[40] A. Herbert,et al. RNA Processing in Evolution: The Logic of Soft‐Wired Genomes a , 1999, Annals of the New York Academy of Sciences.
[41] F. Neidhardt,et al. Escherichia coli proteome analysis using the gene‐protein database , 1997, Electrophoresis.
[42] W. Müller-Esterl,et al. Correlations in Palmitoylation and Multiple Phosphorylation of Rat Bradykinin B2 Receptor in Chinese Hamster Ovary Cells* , 1999, The Journal of Biological Chemistry.
[43] C Giersch. Mathematical modelling of metabolism. , 2000, Current opinion in plant biology.
[44] C. Watanabe,et al. Identifying proteins from two-dimensional gels by molecular mass searching of peptide fragments in protein sequence databases. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[45] F. McLafferty,et al. High-resolution electrospray mass spectra of large molecules , 1991 .
[46] M. Emmett,et al. Identification of intact proteins in mixtures by alternated capillary liquid chromatography electrospray ionization and LC ESI infrared multiphoton dissociation Fourier transform ion cyclotron resonance mass spectrometry. , 1999, Analytical chemistry.
[47] N. Packer,et al. Protein phosphorylation: technologies for the identification of phosphoamino acids. , 1998, Journal of chromatography. A.
[48] J. Whitelegge,et al. Electrospray‐ionization mass spectrometry of intact intrinsic membrane proteins , 1998, Protein science : a publication of the Protein Society.
[49] Linda M. Thienpont,et al. Applications of isotope dilution-mass spectrometry in clinical chemistry, pharmacokinetics, and toxicology , 1992 .
[50] M. Münchbach,et al. Proteome analysis of heat shock protein expression in Bradyrhizobium japonicum. , 1999, European journal of biochemistry.
[51] U. Hellman,et al. Improvement of an "In-Gel" digestion procedure for the micropreparation of internal protein fragments for amino acid sequencing. , 1995, Analytical biochemistry.
[52] R. Henderson,et al. Identification of a peptide recognized by five melanoma-specific human cytotoxic T cell lines. , 1994, Science.
[53] M E Belov,et al. Zeptomole-sensitivity electrospray ionization--Fourier transform ion cyclotron resonance mass spectrometry of proteins. , 2000, Analytical chemistry.
[54] H. Naora,et al. Involvement of ribosomal proteins in regulating cell growth and apoptosis: Translational modulation or recruitment for extraribosomal activity? , 1999, Immunology and cell biology.
[55] Pavel A. Pevzner,et al. De Novo Peptide Sequencing via Tandem Mass Spectrometry , 1999, J. Comput. Biol..
[56] R. Stoffel,et al. Phosphatidylinositol 4,5-Bisphosphate (PIP2)-enhanced G Protein-coupled Receptor Kinase (GRK) Activity: LOCATION, STRUCTURE, AND REGULATION OF THE PIP2 BINDING SITE DISTINGUISHES THE GRK SUBFAMILIES* , 1996, The Journal of Biological Chemistry.
[57] N. Anderson,et al. Proteome and proteomics: New technologies, new concepts, and new words , 1998, Electrophoresis.
[58] Preparing 2-D protein extracts from yeast. , 1999, Methods in molecular biology.
[59] G. Lubec,et al. Two‐dimensional map of human brain proteins , 1999, Electrophoresis.
[60] What remains to be discovered , 1998 .
[61] Todd Smith,et al. The Prostate Expression Database (PEDB): status and enhancements in 2000 , 2000, Nucleic Acids Res..
[62] B. Spengler,et al. Sequencing of peptides phosphorylated on serines and threonines by post-source decay in matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. , 1999, Journal of mass spectrometry : JMS.
[63] Alison Abbott,et al. A post-genomic challenge: learning to read patterns of protein synthesis , 1999, Nature.
[64] R. Aebersold,et al. Microfabricated device coupled with an electrospray ionization quadrupole time-of-flight mass spectrometer: protein identifications based on enhanced-resolution mass spectrometry and tandem mass spectrometry data. , 1998, Rapid communications in mass spectrometry : RCM.
[65] S. Gygi,et al. Absolute quantitation of 2-D protein spots. , 1999, Methods in molecular biology.
[66] R. Lefkowitz,et al. Identification of the G Protein-coupled Receptor Kinase Phosphorylation Sites in the Human β2-Adrenergic Receptor* , 1996, The Journal of Biological Chemistry.
[67] H J Mollenkopf,et al. A dynamic two‐dimensional polyacrylamide gel electrophoresis database: The mycobacterial proteome via Internet , 1999, Electrophoresis.
[68] M. Busman,et al. Mass spectrometric analysis of integral membrane proteins: Application to complete mapping of bacteriorhodopsins and rhodopsin , 1998, Protein science : a publication of the Protein Society.
[69] M. Wilm,et al. Error-tolerant identification of peptides in sequence databases by peptide sequence tags. , 1994, Analytical chemistry.
[70] S. Stevens,et al. Purification of the yeast U4/U6.U5 small nuclear ribonucleoprotein particle and identification of its proteins. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[71] A Bairoch,et al. High-throughput mass spectrometric discovery of protein post-translational modifications. , 1999, Journal of molecular biology.
[72] M J O'Hare,et al. Proteomic definition of normal human luminal and myoepithelial breast cells purified from reduction mammoplasties. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[73] Marc R. Wilkins,et al. Proteome Research: New Frontiers in Functional Genomics , 1997, Principles and Practice.
[74] D. Hochstrasser,et al. Modeling peptide mass fingerprinting data using the atomic composition of peptides , 1999, Electrophoresis.
[75] Thomas Meitinger,et al. MITOP, the mitochondrial proteome database: 2000 update , 2000, Nucleic Acids Res..
[76] D. N. Perkins,et al. Probability‐based protein identification by searching sequence databases using mass spectrometry data , 1999, Electrophoresis.
[77] M. Wilkins,et al. Progress with gene‐product mapping of the Mollicutes: Mycoplasma genitalium , 1995, Electrophoresis.
[78] V Hatzimanikatis,et al. Proteomics: Theoretical and Experimental Considerations , 1999, Biotechnology progress.
[79] C. Fenselau,et al. Sequencing electroblotted proteins by tandem mass spectrometry. , 1995, Rapid communications in mass spectrometry : RCM.
[80] J. Reilly,et al. Observation of Escherichia coli ribosomal proteins and their posttranslational modifications by mass spectrometry. , 1999, Analytical biochemistry.
[81] Michael Y. Galperin,et al. Functional genomics and enzyme evolution , 2004, Genetica.
[82] P. Jackson,et al. Two-dimensional polyacrylamide gel electrophoresis of proteins labeled with the fluorophore monobromobimane prior to first-dimensional isoelectric focusing: imaging of the fluorescent protein spot patterns using a cooled charge-coupled device. , 1993, Analytical biochemistry.
[83] J. Yates,et al. Identifying the major proteome components of Haemophilus influenzae type‐strain NCTC 8143 , 1997, Electrophoresis.
[84] M. Emmett,et al. Electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry. , 1999, Annual review of physical chemistry.
[85] J. Yates,et al. Direct analysis of protein complexes using mass spectrometry , 1999, Nature Biotechnology.
[86] A. Shevchenko,et al. Two‐dimensional gel protein database of Saccharomyces cerevisiae (update 1999) , 1999, Electrophoresis.
[87] C. Ericsson. 2-D protein extracts from Drosophila melanogaster. , 1999, Methods in molecular biology.
[88] B Herbert,et al. Advances in protein solubilisation for two‐dimensional electrophoresis , 1999, Electrophoresis.
[89] Interpretation of matrix-assisted laser desorption/ionization postsource decay spectra of charge-derivatized peptides: Some examples of tris[(2,4,6-trimethoxyphenyl) phosphonium]-tagged proteolytic digestion products of phosphoenolpyruvate carboxykinase , 2000, Journal of the American Society for Mass Spectrometry.
[90] Ron D. Appel,et al. The 1999 SWISS-2DPAGE database update , 2000, Nucleic Acids Res..
[91] B. Palsson,et al. Assessment of the metabolic capabilities of Haemophilus influenzae Rd through a genome-scale pathway analysis. , 2000, Journal of theoretical biology.
[92] M. Mann. A shortcut to interesting human genes: peptide sequence tags, expressed-sequence tags and computers. , 1996, Trends in biochemical sciences.
[93] A. Toker. Signaling through protein kinase C. , 1998, Frontiers in bioscience : a journal and virtual library.
[94] Jacquelyn S. Fetrow,et al. Structural genomics and its importance for gene function analysis , 2000, Nature Biotechnology.
[95] R. Crouch,et al. Mass spectrometric identification of phosphorylation sites in bleached bovine rhodopsin. , 1993, Biochemistry.
[96] R. Cotter,et al. Mass Spectrometry , 1992, Bio/Technology.
[97] R. Faull,et al. Comparative proteome analysis of the hippocampus implicates chromosome 6q in schizophrenia , 2000, Molecular Psychiatry.
[98] T. Kirley. Reduction and fluorescent labeling of cyst(e)ine-containing proteins for subsequent structural analyses. , 1989, Analytical biochemistry.
[99] K. Ito,et al. A class of integral membrane proteins will be overlooked by the 'proteome' study that is based on two-dimensional gel electrophoresis. , 1999, Molecular Microbiology.
[100] T. Keough,et al. Sequencing of sulfonic acid derivatized peptides by electrospray mass spectrometry , 2000, Rapid communications in mass spectrometry : RCM.
[101] A. Görg,et al. The current state of two‐dimensional electrophoresis with immobilized pH gradients , 2000, Electrophoresis.
[102] F. Hillenkamp,et al. IR-MALDI-mass analysis of electroblotted proteins directly from the membrane: comparison of different membranes, application to on-membrane digestion, and protein identification by database searching. , 1999, Analytical chemistry.
[103] Federico Brianza,et al. Functional proteomics of signal transduction by membrane receptors , 1999, Electrophoresis.
[104] M. Mann,et al. Analysis of receptor signaling pathways by mass spectrometry: identification of vav-2 as a substrate of the epidermal and platelet-derived growth factor receptors. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[105] J E Bailey,et al. Mathematical Modeling and Analysis in Biochemical Engineering: Past Accomplishments and Future Opportunities , 1998, Biotechnology progress.
[106] T. Ørntoft,et al. A COMPREHENSIVE PROTEIN RESSOURCE FOR THE STUDY OF BLADDER CANCER : HTTP ://BIOBASE.DK/CGI-BIN/CELL , 1999 .
[107] J. Florini,et al. Variation Among Cell Types in the Signaling Pathways by which IGF-I Stimulates Specific Cellular Responses* , 1999, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.
[108] R D Appel,et al. Improving protein identification from peptide mass fingerprinting through a parameterized multi‐level scoring algorithm and an optimized peak detection , 1999, Electrophoresis.
[109] J. Bell,et al. SR protein kinases: the splice of life. , 1999, Biochemistry and cell biology = Biochimie et biologie cellulaire.
[110] T. Rabilloud. Use of thiourea to increase the solubility of membrane proteins in two‐dimensional electrophoresis , 1998, Electrophoresis.
[111] J. Watson,et al. Charge derivatization of peptides for analysis by mass spectrometry. , 1998, Mass spectrometry reviews.
[112] A. Braun,et al. Structure of the bradykinin B2 receptors' amino terminus. , 1996, Biochemistry.
[113] J. Vohradský,et al. Point pattern matching in the analysis of two‐dimensional gel electropherograms , 1999, Electrophoresis.
[114] Wolfgang Ziegler,et al. Multiple pathways control protein kinase C phosphorylation , 2000, The EMBO journal.
[115] K. Palczewski,et al. Structural and Enzymatic Aspects of Rhodopsin Phosphorylation (*) , 1996, The Journal of Biological Chemistry.
[116] J. Zeikus,et al. Evaluation of charge derivatization of a proteolytic protein digest for improved mass spectrometric analysis: de novo sequencing by matrix-assisted laser desorption/ionization post-source decay mass spectrometry. , 1999, Journal of mass spectrometry : JMS.
[117] T. Rabilloud,et al. Silver Staining of 2D Electrophoresis Gels. , 2021, Methods in molecular biology.
[118] Jean-Charles Sanchez,et al. Two-Dimensional Electrophoresis: The State of the Art and Future Directions , 1997 .
[119] P. Cao,et al. Phosphopeptide analysis by on-line immobilized metal-ion affinity chromatography-capillary electrophoresis-electrospray ionization mass spectrometry. , 1999, Journal of chromatography. A.
[120] Bernhard O. Palsson,et al. Bioinformatics: What lies beyond bioinformatics? , 1997, Nature Biotechnology.
[121] H. Niwa,et al. Phosphopeptide sequencing by in-source decay spectrum in delayed extraction matrix-assisted laser desorption ionization time-of-flight mass spectrometry. , 2000, Analytical biochemistry.
[122] T. Jukes,et al. The neutral theory of molecular evolution. , 2000, Genetics.
[123] S. Gygi,et al. Correlation between Protein and mRNA Abundance in Yeast , 1999, Molecular and Cellular Biology.
[124] S. Gygi,et al. An integrated microfluidics-tandem mass spectrometry system for automated protein analysis. , 1998, Analytical chemistry.
[125] M. Mann,et al. A generic strategy to analyze the spatial organization of multi-protein complexes by cross-linking and mass spectrometry. , 2000, Analytical chemistry.
[126] J. Hacia. Resequencing and mutational analysis using oligonucleotide microarrays , 1999, Nature Genetics.
[127] F Hillenkamp,et al. Analysis of proteins by direct-scanning infrared-MALDI mass spectrometry after 2D-PAGE separation and electroblotting. , 1997, Analytical chemistry.
[128] A. Simoes-Barbosa,et al. Solubilization of delipidated macrophage membrane proteins for analysis by two‐dimensional electrophoresis , 2000, Electrophoresis.
[129] D. Hochstrasser,et al. Towards an automated approach for protein identification in proteome projects , 1998, Electrophoresis.
[130] D. Hochstrasser,et al. Current challenges and future applications for protein maps and post‐translational vector maps in proteome projects , 1996, Electrophoresis.
[131] Michael E. Cusick,et al. The Yeast Proteome Database (YPD) and Caenorhabditis elegans Proteome Database (WormPD): comprehensive resources for the organization and comparison of model organism protein information , 2000, Nucleic Acids Res..
[132] M Gerstein,et al. Advances in structural genomics. , 1999, Current opinion in structural biology.
[133] Y. Shiio,et al. Epitope tagging. , 1995, Methods in enzymology.
[134] Peter Roepstorff,et al. Mapping and identification of HeLa cell proteins separated by immobilized pH‐gradient two‐dimensional gel electrophoresis and construction of a two‐dimensional polyacrylamide gel electrophoresis database , 1999, Electrophoresis.
[135] G. Anderson,et al. Initial implementation of an electrodynamic ion funnel with fourier transform ion cyclotron resonance mass spectrometry , 2000, Journal of the American Society for Mass Spectrometry.
[136] S. Steiner,et al. Expression profiling in toxicology--potentials and limitations. , 2000, Toxicology letters.
[137] E V Koonin,et al. Protein fold recognition using sequence profiles and its application in structural genomics. , 2000, Advances in protein chemistry.
[138] James C. Schaff,et al. The Virtual Cell , 1998, Pacific Symposium on Biocomputing.
[139] W. Blackstock,et al. Proteomics: quantitative and physical mapping of cellular proteins. , 1999, Trends in biotechnology.
[140] T. Hunkapiller,et al. Peptide mass maps: a highly informative approach to protein identification. , 1993, Analytical biochemistry.
[141] R. Aebersold,et al. Microfabricated polymer devices for automated sample delivery of peptides for analysis by electrospray ionization tandem mass spectrometry. , 1999, Analytical chemistry.
[142] F. Lottspeich,et al. Ultraviolet matrix assisted laser desorption ionization‐mass spectrometry of electroblotted proteins , 1996, Electrophoresis.
[143] D. Hochstrasser,et al. Preparation and solubilization of body fluids for 2-D. , 1999, Methods in molecular biology.
[144] M. Mann,et al. Identifying proteins and post-translational modifications by mass spectrometry. , 1998, Current opinion in structural biology.
[145] B. Palsson,et al. Toward Metabolic Phenomics: Analysis of Genomic Data Using Flux Balances , 1999, Biotechnology progress.
[146] M. Molloy,et al. Membrane proteins and proteomics: Un amour impossible? , 2000, Electrophoresis.
[147] Y. Hannun,et al. Visualization of Dynamic Trafficking of a Protein Kinase C βII/Green Fluorescent Protein Conjugate Reveals Differences in G Protein-coupled Receptor Activation and Desensitization* , 1998, The Journal of Biological Chemistry.
[148] R. Baserga,et al. Differentiation and malignant transformation: Two roads diverged in a wood , 1999, Journal of cellular biochemistry.
[149] D. Fell,et al. A general definition of metabolic pathways useful for systematic organization and analysis of complex metabolic networks , 2000, Nature Biotechnology.
[150] Amos Bairoch,et al. Detailed peptide characterization using PEPTIDEMASS – a World‐Wide‐Web‐accessible tool , 1997, Electrophoresis.
[151] M. Mann,et al. Mapping of phosphorylation sites of gel-isolated proteins by nanoelectrospray tandem mass spectrometry: potentials and limitations. , 1999, Analytical chemistry.
[152] A. Newton,et al. Regulation of protein kinase C. , 1997, Current opinion in cell biology.
[153] D. Hochstrasser,et al. Two‐dimensional gel electrophoresis for proteome projects: The effects of protein hydrophobicity and copy number , 1998, Electrophoresis.
[154] R. Aebersold,et al. Nanoflow solvent gradient delivery from a microfabricated device for protein identifications by electrospray ionization mass spectrometry. , 1998, Analytical chemistry.
[155] E. Marcotte,et al. Computational genetics: finding protein function by nonhomology methods. , 2000, Current opinion in structural biology.
[156] V. Regitz-Zagrosek,et al. A two‐dimensional electrophoresis database of rat heart proteins , 1999, Electrophoresis.
[157] P. Courchesne,et al. Identification of proteins by matrix-assisted laser desorption/ionization mass spectrometry using peptide and fragment ion masses. , 1999, Methods in molecular biology.
[158] F. Neidhardt,et al. Preparation of Escherichia coli samples for 2-D gel analysis. , 1999, Methods in molecular biology.
[159] Peter R. Baker,et al. Role of accurate mass measurement (+/- 10 ppm) in protein identification strategies employing MS or MS/MS and database searching. , 1999, Analytical chemistry.
[160] J R Yates,et al. Protein structure analysis by mass spectrometry. , 1996, Methods in enzymology.
[161] R D Appel,et al. Two‐dimensional electrophoresis resources available from ExPASy , 1999, Electrophoresis.
[162] J. Celis,et al. 2D protein electrophoresis: can it be perfected? , 1999, Current opinion in biotechnology.
[163] S. Cordwell,et al. Subproteomics based upon protein cellular location and relative solubilities in conjunction with composite two‐dimensional electrophoresis gels , 2000, Electrophoresis.
[164] P. Parker,et al. The extended protein kinase C superfamily. , 1998, The Biochemical journal.
[165] W. Tansey. How Cells Use Proteolysis to Control Their Growth , 1999, Molecular medicine.
[166] J. Pines,et al. Four-dimensional control of the cell cycle , 1999, Nature Cell Biology.
[167] A L Burlingame,et al. Direct mass spectrometric peptide profiling and sequencing of single neurons reveals differential peptide patterns in a small neuronal network. , 1998, Biochemistry.
[168] Richard C. Strohman,et al. The coming Kuhnian revolution in biology , 1997, Nature Biotechnology.
[169] P. Roepstorff. Mass spectrometry in the analysis of peptides and proteins, past and present. , 1996, Methods in molecular biology.
[170] H. Watarai,et al. Proteomic approach to the identification of cell membrane proteins , 2000, Electrophoresis.
[171] W. G. Bryson,et al. Improved protein solubility in two‐dimensional electrophoresis using tributyl phosphine as reducing agent , 1998, Electrophoresis.
[172] T Laurell,et al. Integrated microanalytical technology enabling rapid and automated protein identification. , 2000, Analytical chemistry.
[173] T. Keough,et al. A method for high-sensitivity peptide sequencing using postsource decay matrix-assisted laser desorption ionization mass spectrometry. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[174] L. Kauvar,et al. Modulating protein kinase C signal transduction. , 1998, Advances in pharmacology.
[175] Y. Hannun,et al. An Essential Role for Autophosphorylation in the Dissociation of Activated Protein Kinase C from the Plasma Membrane* , 1998, The Journal of Biological Chemistry.
[176] George M. Church,et al. Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K‐12 , 1997, Electrophoresis.
[177] U. Hellman,et al. Sample preparation by SDS/PAGE and in-gel digestion. , 2000, EXS.
[178] D. Touati,et al. Coupling 2D SDS-PAGE with CNBr cleavage and MALDI-TOFMS: a strategy applied to the identification of proteins induced by a hypochlorous acid stress in Escherichia coli. , 1998, Analytical chemistry.
[179] William A Gahl,et al. Genotypes and phenotypes , 2001, Genetics in Medicine.
[180] I. Gromova,et al. A comprehensive protein ressource for the study of bladder cancer: http://biobase.dk/cgi‐bin/celis , 1999 .
[181] D. Ramkrishna,et al. Mathematical models of metabolic pathways. , 1999, Current opinion in biotechnology.
[182] R. Heinrich,et al. Metabolic Pathway Analysis: Basic Concepts and Scientific Applications in the Post‐genomic Era , 1999, Biotechnology progress.
[183] Alan Dove,et al. Proteomics: translating genomics into products? , 1999, Nature Biotechnology.
[184] Annabel E. Todd,et al. From protein structure to function. , 1999, Current opinion in structural biology.
[185] Ruedi Aebersold,et al. High throughput protein characterization by automated reverse‐phase chromatography/electrospray tandem mass spectrometry , 1998, Protein science : a publication of the Protein Society.
[186] C. Adessi,et al. Improvement of the solubilization of proteins in two‐dimensional electrophoresis with immobilized pH gradients , 2006, Electrophoresis.
[187] D. Pappin,et al. The potential use of laser capture microdissection to selectively obtain distinct populations of cells for proteomic analysis — Preliminary findings , 1999, Electrophoresis.
[188] Amess,et al. Proteomics: a major new technology for the drug discovery process. , 1999, Drug discovery today.
[189] Ting Chen,et al. Modeling Gene Expression with Differential Equations , 1998, Pacific Symposium on Biocomputing.
[190] Josette Banroques,et al. Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6·U5] tri‐snRNP , 1999, The EMBO journal.
[191] A. Hinnebusch,et al. Identification of phosphorylation sites in proteins separated by polyacrylamide gel electrophoresis. , 1998, Analytical chemistry.
[192] Pierre Thibault,et al. Rapid and sensitive separation of trace level protein digests using microfabricated devices coupled to a quadrupole ‐ time‐of‐flight mass spectrometer , 2000, Electrophoresis.
[193] T. Rabilloud. Solubilization of proteins in 2-D electrophoresis. An outline. , 1999, Methods in molecular biology.
[194] M. Mann,et al. Proteomics to study genes and genomes , 2000, Nature.
[195] P Berndt,et al. Reliable automatic protein identification from matrix‐assisted laser desorption/ionization mass spectrometric peptide fingerprints , 1999, Electrophoresis.
[196] Pumin Zhang,et al. The cell cycle and development: redundant roles of cell cycle regulators. , 1999, Current opinion in cell biology.
[197] R. Aebersold,et al. Protein identification with a single accurate mass of a cysteine-containing peptide and constrained database searching. , 2000, Analytical chemistry.
[198] Daniel Teichroew,et al. Mining protein data from two‐dimensional gels: Tools for systematic post‐planned analyses , 1999 .
[199] A. Burlingame,et al. Rapid mass spectrometric peptide sequencing and mass matching for characterization of human melanoma proteins isolated by two-dimensional PAGE. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[200] M L Shuler,et al. Single-cell models: promise and limitations. , 1999, Journal of biotechnology.
[201] J. Slonczewski,et al. Acid and base regulation in the proteome of Escherichia coli. , 1999, Novartis Foundation symposium.
[202] J. Bailey,et al. Toward a science of metabolic engineering , 1991, Science.
[203] P. Puri,et al. Novel mutations of the endothelin-B receptor gene in isolated patients with Hirschsprung's disease. , 1996, Human molecular genetics.
[204] J. Godovac-Zimmermann,et al. Post-translational Modifications of Endothelin Receptor B from Bovine Lungs Analyzed by Mass Spectrometry* , 1998, The Journal of Biological Chemistry.
[205] M. Frank,et al. Energy-sensitive cryogenic detectors for high-mass biomolecule mass spectrometry. , 1999, Mass spectrometry reviews.
[206] C. Robinson,et al. Disassembly of intact multiprotein complexes in the gas phase. , 1999, Current opinion in structural biology.
[207] L. Liotta,et al. Sensitive immunoassay of tissue cell proteins procured by laser capture microdissection. , 2000, The American journal of pathology.
[208] M. Kazanietz,et al. New insights into the regulation of protein kinase C and novel phorbol ester receptors , 1999, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[209] H. Hennecke,et al. Classifying symbiotic proteins from Bradyrhizobium japonicum into functional groups by proteome analysis of altered gene expression levels , 1999, Electrophoresis.
[210] I. Humphery-Smith,et al. Proteomic ‘contigs’ of Ochrobactrum anthropi, application of extensive pH gradients , 1997, Electrophoresis.
[211] J R Yates,et al. Automated protein identification using microcolumn liquid chromatography-tandem mass spectrometry. , 1999, Methods in molecular biology.
[212] P. Hains,et al. The microbial proteome database — an automated laboratory catalogue for monitoring protein expression in bacteria , 1999, Electrophoresis.
[213] M S Boguski,et al. Biosequence exegesis. , 1999, Science.
[214] John Quackenbush,et al. Gene Index analysis of the human genome estimates approximately 120,000 genes , 2000, Nature Genetics.
[215] Wei Zhou,et al. Characterization of the Yeast Transcriptome , 1997, Cell.
[216] D. Hochstrasser,et al. Progress with proteome projects: why all proteins expressed by a genome should be identified and how to do it. , 1996, Biotechnology & genetic engineering reviews.
[217] M. Ramsby,et al. Differential detergent fractionation of eukaryotic cells. Analysis by two-dimensional gel electrophoresis. , 1999, Methods in molecular biology.
[218] P. Righetti,et al. Isoelectric focusing in immobilized pH gradients: an update. , 1997, Journal of chromatography. B, Biomedical sciences and applications.
[219] J. Jorgenson,et al. Separation and identification of peptides in single neurons by microcolumn liquid chromatography-matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and postsource decay analysis. , 1998, Analytical chemistry.
[220] Igor Goryanin,et al. Mathematical simulation and analysis of cellular metabolism and regulation , 1999, Bioinform..
[221] R. Hammer,et al. Targeted and natural (piebald-lethal) mutations of endothelin-B receptor gene produce megacolon associated with spotted coat color in mice , 1994, Cell.
[222] Intrahelical arrangement in the integral membrane protein rhodopsin investigated by site-specific chemical cleavage and mass spectrometry. , 2000, Biochemistry.
[223] A. D. de Jong,et al. Sheathless preconcentration-capillary zone electrophoresis-mass spectrometry applied to peptide analysis. , 1999, Journal of the American Society for Mass Spectrometry.
[224] R. Strohman. Epigenesis: The Missing Beat in Biotechnology? , 1994, Bio/Technology.
[225] D. Hochstrasser,et al. Extraction of membrane proteins by differential solubilization for separation using two‐dimensional gel electrophoresis , 1998, Electrophoresis.
[226] M. Görlach,et al. Functional proteomics analysis of signal transduction pathways of the platelet-derived growth factor beta receptor. , 1999, Biochemistry.
[227] Masashi Yanagisawa,et al. A missense mutation of the endothelin-B receptor gene in multigenic hirschsprung's disease , 1994, Cell.
[228] G. Anderson,et al. High-mass-measurement accuracy and 100% sequence coverage of enzymatically digested bovine serum albumin from an ESI-FTICR mass spectrum. , 1999, Analytical chemistry.
[229] A. Gooley,et al. Extraction of Escherichia coli proteins with organic solvents prior to two‐dimensional electrophoresis , 1999, Electrophoresis.
[230] K. Yamane,et al. Proteome analysis of Bacillus subtilis extracellular proteins: a two-dimensional protein electrophoretic study. , 2000, Microbiology.
[231] J. Asara,et al. Enhanced detection of phosphopeptides in matrix-assisted laser desorption/ionization mass spectrometry using ammonium salts , 1999, Journal of the American Society for Mass Spectrometry.
[232] J Moult,et al. From fold to function. , 2000, Current opinion in structural biology.
[233] Stephen A. Martin,et al. Sensitivity and mass accuracy for proteins analyzed directly from polyacrylamide gels: Implications for proteome mapping , 1997, Electrophoresis.
[234] M. Eisen,et al. Gene expression informatics —it's all in your mine , 1999, Nature Genetics.
[235] R. Fleischmann,et al. The Minimal Gene Complement of Mycoplasma genitalium , 1995, Science.
[236] J. Klose,et al. Fractionated extraction of total tissue proteins from mouse and human for 2-D electrophoresis. , 1999, Methods in molecular biology.
[237] M C Duque-Magalhães,et al. [Intracellular proteolysis]. , 1984, Biochimie.
[238] D F Hochstrasser,et al. Toward a clinical molecular scanner for proteome research: parallel protein chemical processing before and during western blot. , 1999, Analytical chemistry.
[239] C. Heckman,et al. The sevenfold way of PKC regulation. , 1998, Cellular signalling.
[240] A. S. Bogachuk,et al. Two adjacent cysteine residues in the C‐terminal cytoplasmic fragment of bovine rhodopsin are palmitylated , 1988, FEBS letters.
[241] Michael Y. Galperin,et al. Who's your neighbor? New computational approaches for functional genomics , 2000, Nature Biotechnology.
[242] M. Boguski,et al. Biosequence exegesis : Genome , 1999 .
[243] F. McLafferty,et al. Efficient sequence analysis of the six gene products (7‐74 kDA) from the escherichia coli thiamin biosynthetic operon by tandem high‐resolution mass spectrometry , 1998, Protein science : a publication of the Protein Society.
[244] F. Cross,et al. Accurate quantitation of protein expression and site-specific phosphorylation. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[245] A. Link,et al. Internal standards for 2-D. , 1999, Methods in molecular biology.
[246] A Bairoch,et al. A molecular scanner to automate proteomic research and to display proteome images. , 1999, Analytical chemistry.
[247] C. Pasquali,et al. Preparative two‐dimensional gel electrophoresis of membrane proteins , 1997, Electrophoresis.
[248] K. Walsh,et al. Locating and identifying posttranslational modifications by in‐source decay during MALDI‐TOF mass spectrometry , 2008, Protein science : a publication of the Protein Society.
[249] P. O’Farrell. High resolution two-dimensional electrophoresis of proteins. , 1975, The Journal of biological chemistry.
[250] C Fenselau,et al. Polyvinylidene difluoride (PVDF): an interface for gel electrophoresis and matrix-assisted laser desorption/ionization mass spectrometry. , 1994, Biochemical Society transactions.
[251] B O Palsson,et al. What lies beyond bioinformatics? , 1999, Proceedings of the First Joint BMES/EMBS Conference. 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Annual Fall Meeting of the Biomedical Engineering Society (Cat. N.
[252] A. Görg,et al. Recent developments in two‐dimensional gel electrophoresis with immobilized pH gradients: Wide pH gradients up to pH 12, longer separation distances and simplified procedures , 1999, Electrophoresis.
[253] S. Gygi,et al. Quantitative analysis of complex protein mixtures using isotope-coded affinity tags , 1999, Nature Biotechnology.
[254] M. Yanagisawa,et al. Novel Mutations of the Endothelin B Receptor Gene in Patients with Hirschsprung’s Disease and Their Characterization* , 1998, The Journal of Biological Chemistry.
[255] D. Mochly‐Rosen,et al. Pharmacologic modulation of protein kinase C isozymes: the role of RACKs and subcellular localisation. , 1999, Pharmacological research.
[256] A. Chakravarti. Endothelin receptor-mediated signaling in hirschsprung disease. , 1996, Human molecular genetics.
[257] J. Watson,et al. Protein sequencing by matrix-assisted laser desorption ionization-postsource decay-mass spectrometry analysis of the N-Tris(2,4,6-trimethoxyphenyl)phosphine-acetylated tryptic digests. , 1999, Analytical biochemistry.
[258] E. Davidson,et al. Organization of an echinoderm Hox gene cluster. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[259] A. Marshall,et al. Counting individual sulfur atoms in a protein by ultrahigh-resolution Fourier transform ion cyclotron resonance mass spectrometry: experimental resolution of isotopic fine structure in proteins. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[260] M. Fitzgerald,et al. Mass spectrometry as a readout of protein structure and function. , 1997, Mass spectrometry reviews.
[261] D. Butler. Celera in talks to launch private sector human proteome project , 2000, Nature.
[262] S Brenner. Biological computation. , 1998, Novartis Foundation symposium.
[263] Denis F. Hochstrasser,et al. Clinical and Biomedical Applications of Proteomics , 1997 .
[264] D. Gerber,et al. Detection of single macromolecules using a cryogenic particle detector coupled to a biopolymer mass spectrometer , 1996 .
[265] J R Yates,et al. Mass spectrometry. From genomics to proteomics. , 2000, Trends in genetics : TIG.
[266] R. Aebersold,et al. Microfabricated modules for sample handling, sample concentration and flow mixing: application to protein analysis by tandem mass spectrometry. , 1999, Journal of biomechanical engineering.
[267] Wang,et al. Proteomics in drug discovery. , 1999, Drug discovery today.
[268] A. Alexander,et al. Polyethylene membrane as a sample support for direct matrix-assisted laser desorption/ionization mass spectrometric analysis of high mass proteins. , 1995, Analytical chemistry.
[269] A. Arkin,et al. Simulation of prokaryotic genetic circuits. , 1998, Annual review of biophysics and biomolecular structure.
[270] L. Epstein,et al. Staining of Preparative 2-D Gels , 1999 .
[271] M. Quadroni,et al. Proteome mapping, mass spectrometric sequencing and reverse transcription-PCR for characterization of the sulfate starvation-induced response in Pseudomonas aeruginosa PAO1. , 1999, European journal of biochemistry.
[272] D. Rouquié,et al. Towards the recovery of hydrophobic proteins on two‐dimensional electrophoresis gels , 1999, Electrophoresis.
[273] D. T. Jones. Protein structure prediction in the postgenomic era. , 2000, Current opinion in structural biology.
[274] A. Marshall,et al. Fourier transform ion cyclotron resonance mass spectrometry: a primer. , 1998, Mass spectrometry reviews.
[275] Michael Y. Galperin,et al. The COG database: a tool for genome-scale analysis of protein functions and evolution , 2000, Nucleic Acids Res..
[276] F. McLafferty,et al. Automated reduction and interpretation of , 2000, Journal of the American Society for Mass Spectrometry.
[277] G. Friso,et al. Analysis of proteins from membrane‐enriched cerebellar preparations by two‐dimensional gel electrophoresis and mass spectrometry , 1999, Electrophoresis.
[278] A. Shevchenko,et al. Peptide sequencing of 2-DE gel-isolated proteins by nanoelectrospray tandem mass spectrometry. , 1999, Methods in molecular biology.
[279] D. Hochstrasser,et al. The dynamic range of protein expression: A challenge for proteomic research , 2000, Electrophoresis.
[280] Andrius Kazlauskas,et al. Diverse Signaling Pathways Activated by Growth Factor Receptors Induce Broadly Overlapping, Rather Than Independent, Sets of Genes , 1999, Cell.
[281] J. Findlay,et al. Phosphorylation of ovine rhodopsin. Identification of the phosphorylated sites. , 1984, The Biochemical journal.
[282] B. Cravatt,et al. Activity-based protein profiling: the serine hydrolases. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[283] D. C. Cameron,et al. Cellular and metabolic engineering , 1993, Applied biochemistry and biotechnology.
[284] Maria Samsonova,et al. NetWork: An Interactive Interface to the Tools for Analysis of Genetic Network Structure and Dynamics , 1999, Pacific Symposium on Biocomputing.
[285] T. Rabilloud. Solubilization of Proteins in 2-D Electrophoresis , 1999 .
[286] F. Neidhardt,et al. Diagnosis of cellular states of microbial organisms using proteomics , 1999, Electrophoresis.