Holliday Junction Processing in Bacteria: Insights from the Evolutionary Conservation of RuvABC, RecG, and RusA

Homologous recombination is a fundamental cellular process that rearranges genes within and between chromosomes, promotes DNA repair, and guides segregation of chromosomes at division. It provides, therefore, a potent evolutionary force that serves both to promote genetic diversity and to conserve

[1]  N. Panayotatos,et al.  An endonuclease specific for single-stranded DNA selectively damages the genomic DNA and induces the SOS response. , 1985, The Journal of biological chemistry.

[2]  R. Gaylord unpublished results , 1985 .

[3]  B. Lang,et al.  A yeast nuclear gene, MRS1, involved in mitochondrial RNA splicing: nucleotide sequence and mutational analysis of two overlapping open reading frames on opposite strands. , 1987, The EMBO journal.

[4]  K. Elborough,et al.  Resolution of synthetic Holliday junctions in DNA by an endonuclease activity from calf thymus. , 1990, The EMBO journal.

[5]  H. Shinagawa,et al.  Escherichia coli RuvC protein is an endonuclease that resolves the Holliday structure. , 1991, The EMBO journal.

[6]  R. G. Lloyd,et al.  Formation and resolution of recombination intermediates by E. coliRecA and RuvC proteins , 1991, Nature.

[7]  R. G. Lloyd,et al.  Conjugational recombination in resolvase-deficient ruvC mutants of Escherichia coli K-12 depends on recG , 1991, Journal of bacteriology.

[8]  R. Sternglanz,et al.  Identification and characterization of yeast mutants and the gene for a cruciform cutting endonuclease. , 1992, The EMBO journal.

[9]  I. Kobayashi,et al.  Nonconservative recombination in Escherichia coli. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[10]  S. West Enzymes and molecular mechanisms of genetic recombination. , 1992, Annual review of biochemistry.

[11]  R. G. Lloyd,et al.  Dissociation of synthetic Holliday junctions by E. coli RecG protein. , 1993, The EMBO journal.

[12]  R. G. Lloyd,et al.  Reverse branch migration of holliday junctions by RecG protein: A new mechanism for resolution of intermediates in recombination and DNA repair , 1993, Cell.

[13]  K. Ikeo,et al.  Cloning of human, mouse and fission yeast recombination genes homologous to RAD51 and recA , 1993, Nature Genetics.

[14]  R. G. Lloyd,et al.  Resolution of Holliday intermediates in recombination and DNA repair: indirect suppression of ruvA, ruvB, and ruvC mutations , 1993, Journal of bacteriology.

[15]  A. Sancar,et al.  Molecular mechanism of transcription-repair coupling. , 1993, Science.

[16]  S. West,et al.  Resolution of holliday junctions by RuvC resolvase: Cleavage specificity and DNA distortion , 1993, Cell.

[17]  R. G. Lloyd,et al.  Processing of intermediates in recombination and DNA repair: identification of a new endonuclease that specifically cleaves Holliday junctions. , 1994, The EMBO journal.

[18]  M. Radman,et al.  Mismatch repair proteins MutS and MutL inhibit RecA-catalyzed strand transfer between diverged DNAs. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[19]  Haruki Nakamura,et al.  Atomic structure of the RuvC resolvase: A holliday junction-specific endonuclease from E. coli , 1994, Cell.

[20]  S. Kowalczykowski,et al.  Biochemistry of homologous recombination in Escherichia coli. , 1994, Microbiological reviews.

[21]  S. West,et al.  Resolution of recombination intermediates by a mammalian activity functionally analogous to Escherichia coli RuvC resolvase. , 1994, The Journal of biological chemistry.

[22]  R. Bennett,et al.  Structural analysis of the RuvC-Holliday junction complex reveals an unfolded junction. , 1995, Journal of molecular biology.

[23]  S. West,et al.  Structure of a multisubunit complex that promotes DNA branch migration , 1995, Nature.

[24]  R. G. Lloyd,et al.  Branch migration of three‐strand recombination intermediates by RecG, a possible pathway for securing exchanges initiated by 3′‐tailed duplex DNA. , 1995, The EMBO journal.

[25]  H. Shinagawa,et al.  Identification of four acidic amino acids that constitute the catalytic center of the RuvC Holliday junction resolvase. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[26]  R. G. Lloyd,et al.  Modulation of recombination and DNA repair by the RecG and PriA helicases of Escherichia coli K-12 , 1996, Journal of bacteriology.

[27]  R. G. Lloyd,et al.  The RecG branch migration protein of Escherichia coli dissociates R-loops. , 1996, Journal of molecular biology.

[28]  R. G. Lloyd,et al.  Crystal Structure of DNA Recombination Protein RuvA and a Model for Its Binding to the Holliday Junction , 1996, Science.

[29]  R. G. Lloyd,et al.  Interactions between RuvA and RuvC at Holliday junctions: inhibition of junction cleavage and formation of a RuvA-RuvC-DNA complex. , 1996, Journal of molecular biology.

[30]  R. G. Lloyd,et al.  Holliday junction resolvases encoded by homologous rusA genes in Escherichia coli K-12 and phage 82. , 1996, Journal of molecular biology.

[31]  M. F. White,et al.  The structure-selectivity and sequence-preference of the junction-resolving enzyme CCE1 of Saccharomyces cerevisiae. , 1996, Journal of molecular biology.

[32]  M. F. White,et al.  Recognition and manipulation of branched DNA structure by junction-resolving enzymes. , 1997, Journal of molecular biology.

[33]  Thomas L. Madden,et al.  Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. , 1997, Nucleic acids research.

[34]  R. G. Lloyd,et al.  DNA binding and helicase domains of the Escherichia coli recombination protein RecG. , 1997, Nucleic acids research.

[35]  M. F. White,et al.  Characterization of a Holliday junction-resolving enzyme from Schizosaccharomyces pombe , 1997, Molecular and cellular biology.

[36]  R. G. Lloyd,et al.  The DNA replication protein PriA and the recombination protein RecG bind D-loops. , 1997, Journal of molecular biology.

[37]  M. Whitby,et al.  A new Holliday junction resolving enzyme from Schizosaccharomyces pombe that is homologous to CCE1 from Saccharomyces cerevisiae. , 1997, Journal of molecular biology.

[38]  H. Shinagawa,et al.  ATP‐dependent resolution of R‐loops at the ColE1 replication origin by Escherichia coli RecG protein, a Holliday junction‐specific helicase , 1997, The EMBO journal.

[39]  R. G. Lloyd,et al.  Sequence Specificity and Biochemical Characterization of the RusA Holliday Junction Resolvase of Escherichia coli * , 1997, The Journal of Biological Chemistry.

[40]  K. Kreuzer,et al.  Bacteriophage T4 UvsW protein is a helicase involved in recombination, repair and the regulation of DNA replication origins , 1997, The EMBO journal.

[41]  R. G. Lloyd,et al.  Recognition and manipulation of branched DNA by the RusA Holliday junction resolvase of Escherichia coli. , 1998, Nucleic acids research.

[42]  R. Huber,et al.  The complete genome of the hyperthermophilic bacterium Aquifex aeolicus , 1998, Nature.

[43]  P. Hegde,et al.  The Institute for Genomic Research , 1998, Current Biology.

[44]  S. West,et al.  Functional interactions between the Holliday junction resolvase and the branch migration motor of Escherichia coli , 1998, The EMBO journal.

[45]  S C West,et al.  Coordinated actions of RuvABC in Holliday junction processing. , 1998, Journal of molecular biology.

[46]  R. G. Lloyd,et al.  Sequence-specificity of Holliday junction resolution: identification of RuvC mutants defective in metal binding and target site recognition. , 1998, Journal of molecular biology.

[47]  H. Shinagawa,et al.  Functional analyses of the domain structure in the Holliday junction binding protein RuvA. , 1998, Structure.

[48]  S. Ehrlich,et al.  Lactococcus lactis phage operon coding for an endonuclease homologous to RuvC , 1998, Molecular microbiology.

[49]  S. West,et al.  Formation of RuvABC–Holliday junction complexes in vitro , 1998, Current Biology.

[50]  S. Ehrlich,et al.  RuvAB Acts at Arrested Replication Forks , 1998, Cell.

[51]  I. Tsaneva,et al.  Holliday junction resolvase in Schizosaccharomyces pombe has identical endonuclease activity to the CCE1 homologue YDC2. , 1998, Nucleic acids research.

[52]  R. G. Lloyd,et al.  Structural similarities between Escherichia coli RuvA protein and other DNA-binding proteins and a mutational analysis of its binding to the holliday junction. , 1998, Journal of molecular biology.

[53]  R. G. Lloyd,et al.  Crystal structure of E.coli RuvA with bound DNA Holliday junction at 6 Å resolution , 1998, Nature Structural Biology.

[54]  L. Pearl,et al.  Crystal structure of an octameric RuvA-Holliday junction complex. , 1998, Molecular cell.

[55]  I. Graham,et al.  lambda Rap protein is a structure-specific endonuclease involved in phage recombination. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[56]  D. Lilley,et al.  Structural recognition and distortion by the DNA junction-resolving enzyme RusA. , 1998, Journal of molecular biology.

[57]  James R. Cole,et al.  A new version of the RDP (Ribosomal Database Project) , 1999, Nucleic Acids Res..

[58]  R. G. Lloyd,et al.  Identification of three aspartic acid residues essential for catalysis by the RusA holliday junction resolvase. , 1999, Journal of molecular biology.