Methods for parallel-detection-based ultrasound-modulated optical tomography.

The research reported here focuses on ultrasound-modulated optical tomography based on parallel speckle detection. Four methods were investigated for signal acquisition and analysis, in which laser speckle statistics was applied. The methods were compared with the previously used four-phase method in the imaging of all-biological-tissue samples, in which the buried objects were also biological tissues. The image quality obtained with these methods was comparable with that obtained with the four-phase method; in addition, these methods have advantages in reducing acquisition time and improving the signal-to-noise ratio.

[1]  L V Wang,et al.  Frequency-swept ultrasound-modulated optical tomography in biological tissue by use of parallel detection. , 2000, Optics letters.

[2]  H U Voss,et al.  Dynamic long-term anticipation of chaotic states. , 2001, Physical review letters.

[3]  Z. Kotler,et al.  Ultrasound tagged light imaging in turbid media in a reflectance geometry. , 2000, Optics letters.

[4]  G. Maret,et al.  Ultrasonic modulation of multiply scattered light , 1995 .

[5]  L V Wang,et al.  Theoretical and experimental studies of ultrasound-modulated optical tomography in biological tissue. , 2000, Applied optics.

[6]  H Kollmus,et al.  Three-body Coulomb problem probed by mapping the Bethe surface in ionizing ion-atom collisions. , 2001, Physical review letters.

[7]  Lihong V. Wang Mechanisms of ultrasonic modulation of multiply scattered coherent light: an analytic model. , 2001 .

[8]  L V Wang,et al.  Frequency-swept ultrasound-modulated optical tomography of scattering media. , 1998, Optics letters.

[9]  Glen William Brooksby,et al.  Comprehensive approach to breast cancer detection using light: photon localization by ultrasound modulation and tissue characterization by spectral discrimination , 1993, Photonics West - Lasers and Applications in Science and Engineering.

[10]  Robert A. Kruger,et al.  Photoacoustic ultrasound: theory , 1994, SPIE LASE.

[11]  X. Zhao,et al.  Ultrasound-modulated optical tomography of absorbing objects buried in dense tissue-simulating turbid media. , 1997, Applied optics.

[12]  Z. Kotler,et al.  Detection of inhomogeneities with ultrasound tagging of light. , 2001, Journal of the Optical Society of America. A, Optics, image science, and vision.

[13]  L V Wang,et al.  Mechanisms of ultrasonic modulation of multiply scattered coherent light: a Monte Carlo model. , 2001, Optics letters.

[14]  Frank K. Tittel,et al.  Laser optoacoustic tomography for medical diagnostics: principles , 1996, Photonics West.

[15]  Lihong V. Wang,et al.  Sonoluminescence tomography of turbid media , 1999, Photonics West - Biomedical Optics.

[16]  S. Lévêque-Fort,et al.  Three-dimensional acousto-optic imaging in biological tissues with parallel signal processing. , 2001, Applied optics.

[17]  Sandrine Leveque-Fort,et al.  In situ local tissue characterization and imaging by backscattering acousto-optic imaging , 2001 .

[18]  Sandrine Leveque-Fort,et al.  Setup for simultaneous imaging of optical and acoustic contrasts in biological tissues , 2001, SPIE BiOS.

[19]  G. Mahan,et al.  Ultrasonic tagging of light: theory. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[20]  Azriel Z. Genack,et al.  Acousto-optic tomography with multiply scattered light , 1997 .

[21]  F. D. de Mul,et al.  Three-dimensional photoacoustic imaging of blood vessels in tissue. , 1998, Optics letters.

[22]  A. Boccara,et al.  Ultrasonic tagging of photon paths in scattering media: parallel speckle modulation processing. , 1999, Optics letters.

[23]  L V Wang,et al.  Sonoluminescent tomography of strongly scattering media. , 1998, Optics letters.

[24]  S L Jacques,et al.  Continuous-wave ultrasonic modulation of scattered laser light to image objects in turbid media. , 1995, Optics letters.

[25]  J. Goodman Statistical Properties of Laser Speckle Patterns , 1963 .