Soluble epoxide hydrolase inhibition reveals novel biological functions of epoxyeicosatrienoic acids (EETs).
暂无分享,去创建一个
Bruce D Hammock | B. Hammock | K. Schmelzer | C. Morisseau | S. Jinks | Christophe Morisseau | B. Inceoğlu | Bora Inceoglu | Kara R Schmelzer | Steve L Jinks
[1] B. Hammock,et al. The soluble epoxide hydrolase encoded by EPXH2 is a bifunctional enzyme with novel lipid phosphate phosphatase activity , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[2] M. Kluger,et al. Role of cytochrome P-450 in endogenous antipyresis. , 2000, American journal of physiology. Regulatory, integrative and comparative physiology.
[3] B. Hammock,et al. Inhibition of soluble epoxide hydrolase reduces LPS-induced thermal hyperalgesia and mechanical allodynia in a rat model of inflammatory pain. , 2006, Life sciences.
[4] J. Mcgiff,et al. Cytochrome P-450 metabolism of arachidonic acid. , 1991, Annual review of pharmacology and toxicology.
[5] A. Hohmann,et al. Selective activation of cannabinoid CB2 receptors suppresses spinal fos protein expression and pain behavior in a rat model of inflammation , 2003, Neuroscience.
[6] D. Cockayne,et al. Activation of CB2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain: Pain inhibition by receptors not present in the CNS , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[7] B. Borhan,et al. Mechanism of Soluble Epoxide Hydrolase , 1995, The Journal of Biological Chemistry.
[8] A. Basbaum,et al. Molecular mechanisms of nociception , 2001, Nature.
[9] B D Hammock,et al. Soluble Epoxide Hydrolase Regulates Hydrolysis of Vasoactive Epoxyeicosatrienoic Acids , 2000, Circulation research.
[10] B. Hammock,et al. Toxicity of epoxy fatty acids and related compounds to cells expressing human soluble epoxide hydrolase. , 2000, Chemical research in toxicology.
[11] A. Hohmann,et al. Selective Activation of Cannabinoid CB2 Receptors Suppresses Hyperalgesia Evoked by Intradermal Capsaicin , 2004, Journal of Pharmacology and Experimental Therapeutics.
[12] F. Oesch,et al. The N-terminal domain of mammalian soluble epoxide hydrolase is a phosphatase , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[13] A. Molleman,et al. Cannabinoid signalling (review) , 2006 .
[14] B. Hammock,et al. An Orally Active Epoxide Hydrolase Inhibitor Lowers Blood Pressure and Provides Renal Protection in Salt-Sensitive Hypertension , 2005, Hypertension.
[15] J. Casida,et al. Mammalian metabolism and environmental degradation of the juvenoid 1-(4'-ethylphenoxy)-3,7-dimethyl-6,7-epoxy-trans-2-octene and related compounds. , 1974, Journal of agricultural and food chemistry.
[16] B. Borhan,et al. Improved radiolabeled substrates for soluble epoxide hydrolase. , 1995, Analytical biochemistry.
[17] B. Hammock,et al. Epoxide hydrolases: mechanisms, inhibitor designs, and biological roles. , 2005, Annual review of pharmacology and toxicology.
[18] B. Hammock,et al. Soluble epoxide hydrolase is a therapeutic target for acute inflammation. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[19] B. Hammock,et al. Soluble Epoxide Hydrolase Inhibition Lowers Arterial Blood Pressure in Angiotensin II Hypertension , 2002, Hypertension.
[20] B. Hammock,et al. Membrane-bound and soluble-fraction epoxide hydrolases: methodological aspects , 1985 .
[21] J. Willer,et al. Hyperalgesia and allodynia: peripheral mechanisms. , 2005, Joint, bone, spine : revue du rhumatisme.
[22] B. Hammock,et al. Hydration of cis- and trans-epoxymethyl stearates by the cytosolic epoxide hydrase of mouse liver. , 1979, Biochemical and biophysical research communications.
[23] R. Estabrook,et al. The reaction of arachidonic acid epoxides (epoxyeicosatrienoic acids) with a cytosolic epoxide hydrolase. , 1983, Archives of biochemistry and biophysics.
[24] B. Hammock,et al. Epoxide hydrolases: their roles and interactions with lipid metabolism. , 2005, Progress in lipid research.
[25] B. Hammock,et al. Metabolism of monoepoxides of methyl linoleate: bioactivation and detoxification. , 2000, Archives of biochemistry and biophysics.
[26] J. Iliff,et al. Soluble Epoxide Hydrolase Gene Deletion Is Protective Against Experimental Cerebral Ischemia , 2008, Stroke.
[27] M. Fornage,et al. The soluble epoxide hydrolase gene harbors sequence variation associated with susceptibility to and protection from incident ischemic stroke. , 2005, Human molecular genetics.
[28] K. Ley,et al. Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids. , 1999, Science.
[29] B. Hammock,et al. Optimized thiol derivatizing reagent for the mass spectral analysis of disubstituted epoxy fatty acids. , 2001, Journal of chromatography. A.
[30] Bruce D Hammock,et al. Structure of human epoxide hydrolase reveals mechanistic inferences on bifunctional catalysis in epoxide and phosphate ester hydrolysis. , 2004, Biochemistry.
[31] B D Hammock,et al. Binding of Alkylurea Inhibitors to Epoxide Hydrolase Implicates Active Site Tyrosines in Substrate Activation* , 2000, The Journal of Biological Chemistry.
[32] B. Hammock,et al. The simultaneous quantification of cytochrome P450 dependent linoleate and arachidonate metabolites in urine by HPLC-MS/MS DOI 10.1194/jlr.D200018-JLR200 , 2002, Journal of Lipid Research.
[33] B. Hammock,et al. cDNA cloning and expression of a soluble epoxide hydrolase from human liver. , 1993, Archives of biochemistry and biophysics.
[34] B. Borhan,et al. Molecular and Biochemical Evidence for the Involvement of the Asp-333–His-523 Pair in the Catalytic Mechanism of Soluble Epoxide Hydrolase (*) , 1995, The Journal of Biological Chemistry.
[35] J. Meijer,et al. Structural characterization of the human soluble epoxide hydrolase gene (EPHX2). , 1996, Biochemical and biophysical research communications.
[36] T. Vanderah,et al. Inhibition of Inflammatory Hyperalgesia by Activation of Peripheral CB2 Cannabinoid Receptors , 2003, Anesthesiology.
[37] T. Vanderah,et al. CB2 cannabinoid receptor-mediated peripheral antinociception , 2001, Pain.
[38] F. Oesch,et al. An impaired peroxisomal targeting sequence leading to an unusual bicompartmental distribution of cytosolic epoxide hydrolase , 1991, FEBS letters.
[39] B. Hammock,et al. Distribution and properties of a mammalian soluble epoxide hydrase. , 1980, Biochemical pharmacology.
[40] D. Christianson,et al. Detoxification of environmental mutagens and carcinogens: structure, mechanism, and evolution of liver epoxide hydrolase. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[41] A. Molleman,et al. Cannabinoid signalling. , 2006, Life sciences.
[42] L. Gilbert,et al. Soluble mammalian epoxide hydratase: action on juvenile hormone and other terpenoid epoxides. , 1976, Comparative biochemistry and physiology. B, Comparative biochemistry.
[43] B D Hammock,et al. Potent urea and carbamate inhibitors of soluble epoxide hydrolases. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[44] Xiang Fang,et al. Epoxyeicosatrienoic acids (EETs): metabolism and biochemical function. , 2004, Progress in lipid research.