论文信息 - Two dimensional PNA/DNA arrays: estimating the helicity of unusual nucleic acid polymers.

Two dimensional PNA/DNA arrays: estimating the helicity of unusual nucleic acid polymers.

We extend the generality of nucleic acid-based structural nanotechnology by incorporating non-natural nucleic acids into a DNA double crossover (DX) molecule; visualizing two-dimensional arrays of these DX molecules by Atomic Force Microscopy (AFM) enables us to measure the helical repeat of any heteroduplex sequence capable of forming the outer arms of a DX.

Philip S Lukeman | Nadrian C Seeman | Alexander C Mittal

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