A novel method to identify and characterise peptide mimotopes of heat shock protein 70-associated antigens

[1]  A. Saven,et al.  Antibodies selected from combinatorial libraries block a tumor antigen that plays a key role in immunomodulation. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[2]  L. Globa,et al.  Peptide phage display: opportunities for development of personalized anti-cancer strategies. , 2005, Anti-cancer agents in medicinal chemistry.

[3]  Markus Klinger,et al.  Vaccination with cetuximab mimotopes and biological properties of induced anti-epidermal growth factor receptor antibodies. , 2005, Journal of the National Cancer Institute.

[4]  M. Neumaier,et al.  Monoclonal anti-idiotype antibody 6G6.C4 fused to GM-CSF is capable of breaking tolerance to carcinoembryonic antigen (CEA) in CEA-transgenic mice. , 2005, Cancer research.

[5]  H. Pehamberger,et al.  High-molecular-weight melanoma-associated antigen mimotope immunizations induce antibodies recognizing melanoma cells , 2005, Cancer Immunology, Immunotherapy.

[6]  Erica Anderson,et al.  Identification of polypeptides with selective affinity to intact mouse cerebellar granule neurons from a random peptide-presenting phage library , 2004, Journal of Neuroscience Methods.

[7]  K. Foon,et al.  Dendritic Cells Pulsed with an Anti-Idiotype Antibody Mimicking Carcinoembryonic Antigen (CEA) Can Reverse Immunological Tolerance to CEA and Induce Antitumor Immunity in CEA Transgenic Mice , 2004, Cancer Research.

[8]  E. Ruoslahti,et al.  Vascular zip codes in angiogenesis and metastasis. , 2004, Biochemical Society transactions.

[9]  S. Deutscher,et al.  Is phage display technology on target for developing peptide-based cancer drugs? , 2004, Current drug discovery technologies.

[10]  D. Busch,et al.  Melanoma-Reactive Class I-Restricted Cytotoxic T Cell Clones Are Stimulated by Dendritic Cells Loaded with Synthetic Peptides, but Fail to Respond to Dendritic Cells Pulsed with Melanoma-Derived Heat Shock Proteins In Vitro1 , 2004, The Journal of Immunology.

[11]  Kenneth G. C. Smith,et al.  HSP70 peptide binding mutants separate antigen delivery from dendritic cell stimulation. , 2004, Immunity.

[12]  S. Todryk,et al.  Facets of heat shock protein 70 show immunotherapeutic potential , 2003, Immunology.

[13]  B. Gazzard,et al.  Disease-associated dendritic cells respond to disease-specific antigens through the common heat shock protein receptor. , 2003, Blood.

[14]  R. Tiwari,et al.  Peptide mimotopes of oncoproteins as therapeutic agents in breast cancer. , 2003, International journal of molecular medicine.

[15]  C. Nicchitta,et al.  ISO: a critical evaluation of the role of peptides in heat shock/chaperone protein-mediated tumor rejection. , 2003, Current opinion in immunology.

[16]  B. Calvo,et al.  The EGF receptor family--multiple roles in proliferation, differentiation, and neoplasia with an emphasis on HER4. , 2003, Transactions of the American Clinical and Climatological Association.

[17]  Peter J. S. Hutzler,et al.  Tumor-Derived Heat Shock Protein 70 Peptide Complexes Are Cross-Presented by Human Dendritic Cells1 , 2002, The Journal of Immunology.

[18]  Jonathan J. Lewis,et al.  Vaccination of metastatic melanoma patients with autologous tumor-derived heat shock protein gp96-peptide complexes: clinical and immunologic findings. , 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[19]  Zihai Li,et al.  Overcoming immune tolerance to cancer by heat shock protein vaccines. , 2002, Molecular cancer therapeutics.

[20]  Carsten J. Kirschning,et al.  HSP70 as Endogenous Stimulus of the Toll/Interleukin-1 Receptor Signal Pathway* , 2002, The Journal of Biological Chemistry.

[21]  D. Jäger,et al.  Clinical cancer vaccine trials. , 2002, Current opinion in immunology.

[22]  Daniel Hanau,et al.  Heat-shock proteins as activators of the innate immune system. , 2002, Trends in immunology.

[23]  P. Srivastava,et al.  Roles of heat-shock proteins in antigen presentation and cross-presentation. , 2002, Current opinion in immunology.

[24]  Laurence Zitvogel,et al.  Antigen presentation and T cell stimulation by dendritic cells. , 2002, Annual review of immunology.

[25]  P. Srivastava,et al.  Interaction of heat shock proteins with peptides and antigen presenting cells: chaperoning of the innate and adaptive immune responses. , 2002, Annual review of immunology.

[26]  N. Bhardwaj,et al.  Primary Tumor Tissue Lysates Are Enriched in Heat Shock Proteins and Induce the Maturation of Human Dendritic Cells1 , 2001, The Journal of Immunology.

[27]  Suh-Chin Wu,et al.  Neutralizing peptide ligands selected from phage-displayed libraries mimic the conformational epitope on domain III of the Japanese encephalitis virus envelope protein. , 2001, Virus research.

[28]  K. Foon,et al.  Are solid tumor anti-idiotype vaccines ready for prime time? Commentary re: U. Wagner et al., Immunological consolidation of ovarian carcinoma recurrences with monoclonal anti-idiotype antibody ACA125: immune responses and survival in palliative treatment. Clin. Cancer Res., 7: 1154-1162, 2001. , 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

[29]  F. Ma,et al.  [Immunogenicity of phage-displayed tumor antigen-mimic peptide]. , 2001, Zhonghua zhong liu za zhi [Chinese journal of oncology].

[30]  D. Wallwiener,et al.  Immunological consolidation of ovarian carcinoma recurrences with monoclonal anti-idiotype antibody ACA125: immune responses and survival in palliative treatment. See The biology behind: K. A. Foon and M. Bhattacharya-Chatterjee, Are solid tumor anti-idiotype vaccines ready for prime time? Clin. Can , 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

[31]  P. Srivastava,et al.  Heat shock proteins: the 'Swiss Army Knife' vaccines against cancers and infectious agents. , 2001, Vaccine.

[32]  E. Ruoslahti Targeting tumor vasculature with homing peptides from phage display. , 2000, Seminars in cancer biology.

[33]  P. Srivastava,et al.  Heat shock proteins: the fountainhead of innate and adaptive immune responses , 2000, Cell stress & chaperones.

[34]  P. Srivastava,et al.  Heat, heat shock, heat shock proteins and death: a central link in innate and adaptive immune responses. , 2000, Immunology letters.

[35]  L. Eisenbach,et al.  Antitumor vaccination using peptide based vaccines. , 2000, Immunology letters.

[36]  Stuart K. Calderwood,et al.  HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine , 2000, Nature Medicine.

[37]  A. Melcher,et al.  Heat shock proteins refine the danger theory , 2000, Immunology.

[38]  J. Scholefield,et al.  A neoadjuvant clinical trial in colorectal cancer patients of the human anti-idiotypic antibody 105AD7, which mimics CD55. , 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

[39]  E. Ruoslahti,et al.  A peptide mimic of E-selectin ligand inhibits sialyl Lewis X-dependent lung colonization of tumor cells. , 2000, Cancer research.

[40]  A. Melcher,et al.  Heat shock protein 70 induced during tumor cell killing induces Th1 cytokines and targets immature dendritic cell precursors to enhance antigen uptake. , 1999, Journal of immunology.

[41]  B. Fleischer,et al.  In vivo and in vitro activation of T cells after administration of Ag-negative heat shock proteins. , 1999, Journal of immunology.

[42]  A. Melcher,et al.  Tumor immunogenicity is determined by the mechanism of cell death via induction of heat shock protein expression , 1998, Nature Medicine.

[43]  J. Scholefield,et al.  Colorectal cancer vaccines , 1998, The British journal of surgery.

[44]  R. Young,et al.  Heat shock fusion proteins as vehicles for antigen delivery into the major histocompatibility complex class I presentation pathway. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[45]  Pramod K. Srivastava,et al.  Heat Shock Protein–Peptide Complexes, Reconstituted In Vitro, Elicit Peptide-specific Cytotoxic T Lymphocyte Response and Tumor Immunity , 1997, The Journal of experimental medicine.

[46]  J. Sprent,et al.  T Cell Stimulation In Vivo by Lipopolysaccharide (LPS) , 1997, The Journal of experimental medicine.

[47]  P. Srivastava,et al.  Purification of immunogenic heat shock protein 70-peptide complexes by ADP-affinity chromatography. , 1997, Journal of immunological methods.

[48]  Erkki Ruoslahti,et al.  Organ targeting In vivo using phage display peptide libraries , 1996, Nature.

[49]  P. Srivastava,et al.  Heat shock protein 70-associated peptides elicit specific cancer immunity , 1993, The Journal of experimental medicine.

[50]  R. W. Baldwin,et al.  Induction of delayed hypersensitivity to human tumor cells with a human monoclonal anti-idiotypic antibody. , 1991, Journal of the National Cancer Institute.

[51]  J. Scott,et al.  Searching for peptide ligands with an epitope library. , 1990, Science.

[52]  T. Klein,et al.  Interferon-gamma induction by lipopolysaccharide: dependence on interleukin 2 and macrophages. , 1986, Journal of immunology.