Spontaneous and drug-induced apoptosis is mediated by conformational changes of Bax and Bak in B-cell chronic lymphocytic leukemia.
暂无分享,去创建一个
A. López-Guillermo | F. Bosch | E. Campo | E. Montserrat | N. Villamor | D. Colomer | B. Bellosillo | S. Marcé
[1] D. Hossfeld. E.S. Jaffe, N.L. Harris, H. Stein, J.W. Vardiman (eds). World Health Organization Classification of Tumours: Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues , 2002 .
[2] A. Gambotto,et al. Resistance to Granzyme B-mediated Cytochrome c Release in Bak-deficient Cells , 2001, The Journal of experimental medicine.
[3] A. López-Guillermo,et al. Complement-mediated cell death induced by rituximab in B-cell lymphoproliferative disorders is mediated in vitro by a caspase-independent mechanism involving the generation of reactive oxygen species. , 2001, Blood.
[4] I. Herr,et al. Cellular stress response and apoptosis in cancer therapy. , 2001, Blood.
[5] A. Gambotto,et al. A Role for Mitochondrial Bak in Apoptotic Response to Anticancer Drugs* , 2001, The Journal of Biological Chemistry.
[6] B. Wong,et al. Non-steroidal anti-inflammatory drugs induce apoptosis in gastric cancer cells through up-regulation of bax and bak. , 2001, Carcinogenesis.
[7] C. Fegan,et al. Flavopiridol circumvents Bcl‐2 family mediated inhibition of apoptosis and drug resistance in B‐cell chronic lymphocytic leukaemia , 2001, British journal of haematology.
[8] R. Youle,et al. Bax and Bak Coalesce into Novel Mitochondria-Associated Clusters during Apoptosis , 2001, The Journal of cell biology.
[9] J. Hansson,et al. Cisplatin Induces the Proapoptotic Conformation of Bak in a ΔMEKK1-Dependent Manner , 2001, Molecular and Cellular Biology.
[10] S. Korsmeyer,et al. Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death , 2001, Science.
[11] G. Getz,et al. DNA microarrays identification of primary and secondary target genes regulated by p53 , 2001, Oncogene.
[12] A. Godzik,et al. Bcl-B, a Novel Bcl-2 Family Member That Differentially Binds and Regulates Bax and Bak* , 2001, The Journal of Biological Chemistry.
[13] S. Cory,et al. Life-or-death decisions by the Bcl-2 protein family. , 2001, Trends in biochemical sciences.
[14] John Calvin Reed,et al. Bax is a transcriptional target and mediator of c-myc-induced apoptosis. , 2000, Cancer research.
[15] Nico Tjandra,et al. Structure of Bax Coregulation of Dimer Formation and Intracellular Localization , 2000, Cell.
[16] M. Grever,et al. Novel therapies for chronic lymphocytic leukemia in the 21st century. , 2000, Seminars in oncology.
[17] N D Marchenko,et al. Death Signal-induced Localization of p53 Protein to Mitochondria , 2000, The Journal of Biological Chemistry.
[18] L. Romer,et al. Integrin-Mediated Survival Signals Regulate the Apoptotic Function of Bax through Its Conformation and Subcellular Localization , 2000, The Journal of cell biology.
[19] D. Green,et al. p53 Induces Apoptosis by Caspase Activation through Mitochondrial Cytochrome c Release* , 2000, The Journal of Biological Chemistry.
[20] J. Roth,et al. Up-regulation of the proapoptotic mediators Bax and Bak after adenovirus-mediated p53 gene transfer in lung cancer cells. , 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.
[21] K. Muegge,et al. Withdrawal of IL-7 induces Bax translocation from cytosol to mitochondria through a rise in intracellular pH. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[22] E. Montserrat,et al. In vitro evaluation of fludarabine in combination with cyclophosphamide and/or mitoxantrone in B-cell chronic lymphocytic leukemia. , 1999, Blood.
[23] S. Korsmeyer,et al. BCL-2 family members and the mitochondria in apoptosis. , 1999, Genes & development.
[24] Y. Hsu,et al. Conformation of the Bax C‐terminus regulates subcellular location and cell death , 1999, The EMBO journal.
[25] Jean-Claude Martinou,et al. Bid-induced Conformational Change of Bax Is Responsible for Mitochondrial Cytochrome c Release during Apoptosis , 1999, The Journal of cell biology.
[26] B. Corfe,et al. Cell Damage-induced Conformational Changes of the Pro-Apoptotic Protein Bak In Vivo Precede the Onset of Apoptosis , 1999, The Journal of cell biology.
[27] S. Korsmeyer,et al. Regulated Targeting of BAX to Mitochondria , 1998, The Journal of cell biology.
[28] S. Korsmeyer,et al. Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis , 1998, The EMBO journal.
[29] C. Croce,et al. Expression of apoptosis-regulating proteins in chronic lymphocytic leukemia: correlations with In vitro and In vivo chemoresponses. , 1998, Blood.
[30] Y. Hsu,et al. Bax in Murine Thymus Is a Soluble Monomeric Protein That Displays Differential Detergent-induced Conformations* , 1998, The Journal of Biological Chemistry.
[31] John Calvin Reed. Molecular biology of chronic lymphocytic leukemia. , 1998, Seminars in oncology.
[32] D. P. Bentley,et al. Bcl-2/Bax ratios in chronic lymphocytic leukaemia and their correlation with in vitro apoptosis and clinical resistance. , 1997, British Journal of Cancer.
[33] S. Korsmeyer,et al. Bcl-2 and Bax function independently to regulate cell death , 1997, Nature Genetics.
[34] D. Colomer,et al. Involvement of CED-3/ICE proteases in the apoptosis of B-chronic lymphocytic leukemia cells. , 1997, Blood.
[35] Y. Hsu,et al. Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[36] C. Pepper,et al. REGULATION OF CLINICAL CHEMORESISTANCE BY bcl‐2 AND BAX ONCOPROTEINS IN B‐CELL CHRONIC LYMPHOCYTIC LEUKAEMIA , 1996, British journal of haematology.
[37] T. McDonnell,et al. Bcl-2 expression in chronic lymphocytic leukemia and its correlation with the induction of apoptosis and clinical outcome. , 1996, Leukemia.
[38] John Calvin Reed,et al. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene , 1995, Cell.
[39] P. Bernardi,et al. Recent progress on regulation of the mitochondrial permeability transition pore; a cyclosporin-sensitive pore in the inner mitochondrial membrane , 1994, Journal of bioenergetics and biomembranes.
[40] K. Lee,et al. Chlorambucil induced apoptosis in chronic lymphocytic leukemia (CLL) and its relationship to clinical efficacy. , 1994, Leukemia.
[41] M. Story,et al. Induction of apoptotic cell death in chronic lymphocytic leukemia by 2-chloro-2′-deoxyadenosine and 9-β-D-arabinosyl-2-fluoroadenine , 1993 .
[42] M. Story,et al. Induction of apoptotic cell death in chronic lymphocytic leukemia by 2-chloro-2'-deoxyadenosine and 9-beta-D-arabinosyl-2-fluoroadenine. , 1993, Blood.
[43] John Calvin Reed,et al. bcl-2 gene hypomethylation and high-level expression in B-cell chronic lymphocytic leukemia. , 1993, Blood.
[44] G. Gaidano,et al. Na+/H+ antiporter has different properties in human B lymphocytes according to CD5 expression and malignant phenotype , 1991, European journal of immunology.
[45] S. Orrenius,et al. Induction of DNA fragmentation in chronic B-lymphocytic leukemia cells. , 1991, Journal of immunology.
[46] G. Gaidano,et al. Na+/H+ exchange activation mediates the lipopolysaccharide-induced proliferation of human B lymphocytes and is impaired in malignant B-chronic lymphocytic leukemia lymphocytes. , 1989, Journal of immunology.