An improved radiosynthesis of [18F]AV-133: a PET imaging agent for vesicular monoamine transporter 2.

[1]  J. Fowler,et al.  [(11)C]PR04.MZ, a promising DAT ligand for low concentration imaging: Synthesis, efficient (11)C-O-methylation and initial small animal PET studies. , 2009, Bioorganic & medicinal chemistry letters.

[2]  Thomas E. Nichols,et al.  Striatal [11C]dihydrotetrabenazine and [11C]methylphenidate binding in Tourette syndrome , 2009, Neurology.

[3]  Nicholas J Long,et al.  Synthesis of 11C, 18F, 15O, and 13N radiolabels for positron emission tomography. , 2008, Angewandte Chemie.

[4]  J. Seibyl.  Single-photon emission computed tomography and positron emission tomography evaluations of patients with central motor disorders. , 2008, Seminars in nuclear medicine.

[5]  Lisheng Cai,et al.  Chemistry with [18F]Fluoride Ion , 2008 .

[6]  W. Wadsak,et al.  Metabolism and autoradiographic evaluation of [(18)F]FE@CIT: a Comparison with [(123)I]beta-CIT and [(123)I]FP-CIT. , 2008, Nuclear medicine and biology.

[7]  R. Edwards,et al.  Expression and function of the rat vesicular monoamine transporter 2. , 2008, American journal of physiology. Cell physiology.

[8]  T. Grönroos,et al.  Ex vivo evaluation of N-(3-[18F]fluoropropyl)-2 beta-carbomethoxy-3 beta-(4-fluorophenyl)nortropane in rats. , 2008, Nuclear medicine and biology.

[9]  T. Yen,et al.  Clinical acceptance of a molecular imaging agent: a long march with [99mTc]TRODAT. , 2007, Nuclear medicine and biology.

[10]  H. Kung,et al.  Quick assembly of 1,4-diphenyltriazoles as probes targeting beta-amyloid aggregates in Alzheimer's disease. , 2007, Journal of medicinal chemistry.

[11]  H. Kung,et al.  Characterization of optically resolved 9-fluoropropyl-dihydrotetrabenazine as a potential PET imaging agent targeting vesicular monoamine transporters. , 2007, Nuclear medicine and biology.

[12]  H. Kung,et al.  Pharmacokinetics of [(18)F]fluoroalkyl derivatives of dihydrotetrabenazine in rat and monkey brain. , 2007, Nuclear medicine and biology.

[13]  D. Bars.  Fluorine-18 and medical imaging: Radiopharmaceuticals for positron emission tomography , 2006 .

[14]  J. Votaw,et al.  Synthesis, radiosynthesis, and biological evaluation of carbon-11 labeled 2beta-carbomethoxy-3beta-(3'-((Z)-2-haloethenyl)phenyl)nortropanes: candidate radioligands for in vivo imaging of the serotonin transporter with positron emission tomography. , 2006, Journal of medicinal chemistry.

[15]  N. Bohnen,et al.  Positron Emission Tomography of Monoaminergic Vesicular Binding in Aging and Parkinson Disease , 2006, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[16]  H. Kung,et al.  Fluoroalkyl derivatives of dihydrotetrabenazine as positron emission tomography imaging agents targeting vesicular monoamine transporters. , 2006, Nuclear medicine and biology.

[17]  David J. Brooks,et al.  Imaging in Parkinson’s Disease: The Role of Monoamines in Behavior , 2006, Biological Psychiatry.

[18]  M. Kilbourn.  In vivo radiotracers for vesicular neurotransmitter transporters. , 1997, Nuclear medicine and biology.

[19]  S. J. Gatley,et al.  Chiral drugs: comparison of the pharmacokinetics of [11C]d-threo and l-threo-methylphenidate in the human and baboon brain , 1997, Psychopharmacology.

[20]  S. Gilman,et al.  Presynaptic monoaminergic vesicles in Parkinson's disease and normal aging , 1996, Annals of neurology.

[21]  R. Koeppe,et al.  In vivo imaging of the brain vesicular monoamine transporter. , 1995, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[22]  A. Pletscher,et al.  A benzo[a]quinolizine derivative with a neuroleptic-like action on cerebral monoamine turnover. , 1977, The Journal of pharmacology and experimental therapeutics.

[23]  M. Schäfer,et al.  Localization of vesicular monoamine transporter isoforms (VMAT1 and VMAT2) to endocrine cells and neurons in rat , 2007, Journal of Molecular Neuroscience.

[24]  R A Koeppe,et al.  Imaging the vesicular monoamine transporter. , 2001, Advances in neurology.

[25]  C. Kilts,et al.  18F-labeled FECNT: a selective radioligand for PET imaging of brain dopamine transporters. , 2000, Nuclear medicine and biology.

[26]  J. DaSilva,et al.  In vivo binding of [11C]tetrabenazine to vesicular monoamine transporters in mouse brain. , 1992, Life sciences.

[27]  A. Brossi,et al.  Benzoquinolizine Derivatives: a New Class of Monamine Decreasing Drugs With Psychotropic Action , 1962 .