Recent Advances in the Emergence of Nanorobotics in Medicine

[1]  George Musser,et al.  Taming Maxwell's Demon , 1999 .

[2]  J. Kang,et al.  Novel electrical detection of label-free disease marker proteins using piezoresistive self-sensing micro-cantilevers. , 2005, Biosensors & bioelectronics.

[3]  Shekhar Bhansali,et al.  MEMS for biomedical applications , 2012 .

[4]  T. Powers,et al.  The hydrodynamics of swimming microorganisms , 2008, 0812.2887.

[5]  H. Berg Cold Spring Harbor Symposia on Quantitative Biology.: Vol. LII. Evolution of Catalytic Functions. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 1987, ISBN 0-87969-054-2, xix + 955 pp., US $150.00. , 1989 .

[6]  Takemi Tanaka,et al.  Nanomedicine in Cancer , 2011 .

[7]  O. Schmidt,et al.  The smallest man-made jet engine. , 2011, Chemical record.

[8]  Patrice D Cani,et al.  Targeted nanoparticles with novel non-peptidic ligands for oral delivery. , 2013, Advanced drug delivery reviews.

[9]  J E Kipp,et al.  The role of solid nanoparticle technology in the parenteral delivery of poorly water-soluble drugs. , 2004, International journal of pharmaceutics.

[10]  J. Barth,et al.  Rotational and constitutional dynamics of caged supramolecules , 2010, Proceedings of the National Academy of Sciences.

[11]  Bimetallic micromotor autonomously movable in biofuels , 2013, 2013 IEEE 26th International Conference on Micro Electro Mechanical Systems (MEMS).

[12]  N. N. Sharma,et al.  Nanorobot Movement: Challenges and Biologically inspired solutions , 2008 .

[13]  R. Jain,et al.  Delivering nanomedicine to solid tumors , 2010, Nature Reviews Clinical Oncology.

[14]  I. Derényi,et al.  Towards a chemically driven molecular electron pump. , 2001, Physical review letters.

[15]  A. R. Kulkarni,et al.  Biodegradable polymeric nanoparticles as drug delivery devices. , 2001, Journal of controlled release : official journal of the Controlled Release Society.

[16]  M. Prabaharan,et al.  Chitosan-based nanoparticles for tumor-targeted drug delivery. , 2015, International journal of biological macromolecules.

[17]  P. Kantoff,et al.  Cancer nanomedicine: progress, challenges and opportunities , 2016, Nature Reviews Cancer.

[18]  J Szebeni,et al.  Stealth liposomes and long circulating nanoparticles: critical issues in pharmacokinetics, opsonization and protein-binding properties. , 2003, Progress in lipid research.

[19]  K Takakura,et al.  Treatment of severe intraventricular hemorrhage by intraventricular infusion of urokinase. , 1991, Journal of neurosurgery.

[20]  Asim Nisar,et al.  MEMS-based micropumps in drug delivery and biomedical applications , 2008 .

[21]  Wolfgang J. Parak,et al.  Quantum Dot-Based Cell Motility Assay , 2005, Science's STKE.

[22]  S. Gu,et al.  Thiolated trimethyl chitosan nanocomplexes as gene carriers with high in vitro and in vivo transfection efficiency. , 2010, Journal of controlled release : official journal of the Controlled Release Society.

[23]  R. Astumian,et al.  Activation of Na+ and K+ pumping modes of (Na,K)-ATPase by an oscillating electric field. , 1990, The Journal of biological chemistry.

[24]  John G. Gibbs,et al.  Nanopropellers and their actuation in complex viscoelastic media. , 2014, ACS nano.

[25]  Zhirong Zhang,et al.  Efficient mucus permeation and tight junction opening by dissociable "mucus-inert" agent coated trimethyl chitosan nanoparticles for oral insulin delivery. , 2016, Journal of controlled release : official journal of the Controlled Release Society.

[26]  Baoquan Ding,et al.  A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo , 2018, Nature Biotechnology.

[27]  Rajesh Singh,et al.  Nanoparticle-based targeted drug delivery. , 2009, Experimental and molecular pathology.

[28]  Zhiguang Wu,et al.  Self-propelled polymer-based multilayer nanorockets for transportation and drug release. , 2013, Angewandte Chemie.

[29]  P. Hoffmann,et al.  How molecular motors extract order from chaos (a key issues review) , 2016, Reports on progress in physics. Physical Society.

[30]  F. Masood,et al.  Polymeric nanoparticles for targeted drug delivery system for cancer therapy. , 2016, Materials science & engineering. C, Materials for biological applications.

[31]  T Lammers,et al.  Applications of nanoparticles for diagnosis and therapy of cancer. , 2015, The British journal of radiology.

[32]  A. Leshansky,et al.  Swimming by reciprocal motion at low Reynolds number , 2014, Nature Communications.

[33]  G. Stathopoulos,et al.  Liposomal cisplatin combined with paclitaxel versus cisplatin and paclitaxel in non-small-cell lung cancer: a randomized phase III multicenter trial , 2010, Annals of oncology : official journal of the European Society for Medical Oncology.

[34]  U. Kompella,et al.  Functionalized nanosystems for targeted mitochondrial delivery. , 2012, Mitochondrion.

[35]  J. Teissié,et al.  Evidence of voltage-induced channel opening in Na/K ATPase of human erythrocyte membrane , 1980, The Journal of Membrane Biology.

[36]  Euan R Kay,et al.  Rise of the Molecular Machines , 2015, Angewandte Chemie.

[37]  S. Mitragotri,et al.  Role of nanoparticle size, shape and surface chemistry in oral drug delivery. , 2016, Journal of controlled release : official journal of the Controlled Release Society.

[38]  P. Fischer,et al.  Controlled propulsion of artificial magnetic nanostructured propellers. , 2009, Nano letters.

[39]  Morteza Milani,et al.  Magnetic nanoparticles in cancer diagnosis and treatment: a review , 2017, Artificial cells, nanomedicine, and biotechnology.

[40]  O. Schmidt,et al.  Superfast motion of catalytic microjet engines at physiological temperature. , 2011, Journal of the American Chemical Society.

[41]  N. Mishra,et al.  Targeting Aspects of Nanogels: An Overview , 2014 .

[42]  Richard A. Silva,et al.  Unidirectional rotary motion in a molecular system , 1999, Nature.

[43]  T. Mallouk,et al.  Bipolar electrochemical mechanism for the propulsion of catalytic nanomotors in hydrogen peroxide solutions. , 2006, Langmuir : the ACS journal of surfaces and colloids.

[44]  Aristides A. G. Requicha Nanorobots, NEMS, and nanoassembly , 2003 .

[45]  K. Garber Alnylam's RNAi therapy targets amyloid disease , 2015, Nature Biotechnology.

[46]  Gengfeng Zheng,et al.  Multiplexed electrical detection of cancer markers with nanowire sensor arrays , 2005, Nature Biotechnology.

[47]  Salvador Pané,et al.  Catalytic Locomotion of Core-Shell Nanowire Motors. , 2016, ACS nano.

[48]  Mauro Ferrari,et al.  Principles of nanoparticle design for overcoming biological barriers to drug delivery , 2015, Nature Biotechnology.

[49]  Yamuna Krishnan,et al.  Two DNA nanomachines map pH changes along intersecting endocytic pathways inside the same cell. , 2013, Nature nanotechnology.

[50]  P. Wust,et al.  Efficacy and safety of intratumoral thermotherapy using magnetic iron-oxide nanoparticles combined with external beam radiotherapy on patients with recurrent glioblastoma multiforme , 2010, Journal of Neuro-Oncology.

[51]  M. Skwarczynski,et al.  Oral delivery of nanoparticle-based vaccines , 2014, Expert review of vaccines.

[52]  R. Mumper,et al.  Development of idarubicin and doxorubicin solid lipid nanoparticles to overcome Pgp-mediated multiple drug resistance in leukemia. , 2009, Journal of biomedical nanotechnology.

[53]  Longqiu Li,et al.  Visible-light driven Si-Au micromotors in water and organic solvents. , 2017, Nanoscale.

[54]  A. Leshansky,et al.  Highly Efficient Freestyle Magnetic Nanoswimmer. , 2017, Nano letters.

[55]  Y. Assaraf,et al.  Nanomedicine for targeted cancer therapy: towards the overcoming of drug resistance. , 2011, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

[56]  Benedikt F. Seitz,et al.  Undulatory Locomotion of Magnetic Multilink Nanoswimmers. , 2015, Nano letters.

[57]  L. Bezdetnaya,et al.  Anticancer Drug Delivery: An Update on Clinically Applied Nanotherapeutics , 2015, Drugs.

[58]  Drexler Ke,et al.  Molecular engineering: An approach to the development of general capabilities for molecular manipulation. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[59]  A. Niendorf,et al.  Microphysiological testing for chemosensitivity of living tumor cells with multiparametric microsensor chips. , 2003, Cancer detection and prevention.

[60]  Sudesh Kumar Yadav,et al.  Biodegradable polymeric nanoparticles based drug delivery systems. , 2010, Colloids and surfaces. B, Biointerfaces.

[61]  Y. Barenholz Doxil®--the first FDA-approved nano-drug: lessons learned. , 2012, Journal of controlled release : official journal of the Controlled Release Society.

[62]  P. Couvreur,et al.  Nanoparticles in cancer therapy and diagnosis. , 2002, Advanced drug delivery reviews.

[63]  Tony Jun Huang,et al.  Rheotaxis of Bimetallic Micromotors Driven by Chemical-Acoustic Hybrid Power. , 2017, ACS nano.

[64]  Tao Ding,et al.  Light-induced actuating nanotransducers , 2016, Proceedings of the National Academy of Sciences.

[65]  S. Nie,et al.  Therapeutic Nanoparticles for Drug Delivery in Cancer Types of Nanoparticles Used as Drug Delivery Systems , 2022 .

[66]  Ayusman Sen,et al.  Fantastic voyage: designing self-powered nanorobots. , 2012, Angewandte Chemie.

[67]  Christopher Jarzynski,et al.  Work and information processing in a solvable model of Maxwell’s demon , 2012, Proceedings of the National Academy of Sciences.

[68]  Christophe Escudé,et al.  Detection of single DNA molecules by multicolor quantum-dot end-labeling , 2005, Nucleic acids research.

[69]  W. Litchy,et al.  Trial design and rationale for APOLLO, a Phase 3, placebo-controlled study of patisiran in patients with hereditary ATTR amyloidosis with polyneuropathy , 2017, BMC Neurology.

[70]  Qi Shen,et al.  Multifunctional Nanoparticles Loading with Docetaxel and GDC0941 for Reversing Multidrug Resistance Mediated by PI3K/Akt Signal Pathway. , 2017, Molecular pharmaceutics.

[71]  Davison,et al.  Dynamics and energetics of scallop locomotion , 1996, The Journal of experimental biology.

[72]  Miqin Zhang,et al.  Design and fabrication of magnetic nanoparticles for targeted drug delivery and imaging. , 2010, Advanced drug delivery reviews.

[73]  Richard A. Silva,et al.  A Rationally Designed Prototype of a Molecular Motor. , 2000, Journal of the American Chemical Society.

[74]  Passive swimming in viscous oscillatory flows. , 2016, Physical review. E.

[75]  R. Astumian,et al.  Electroconformational coupling: how membrane-bound ATPase transduces energy from dynamic electric fields. , 1988, Annual review of physiology.

[76]  H. Berg,et al.  Bacteria Swim by Rotating their Flagellar Filaments , 1973, Nature.

[77]  Bernard H. Stark,et al.  Mems inertial power generators for biomedical applications , 2006 .

[78]  Hasham S. Sofi,et al.  Development and Characterization of Drug-Loaded Self-Solid Nano-Emulsified Drug Delivery System for Treatment of Diabetes , 2018 .

[79]  Yamuna Krishnan,et al.  A DNA nanomachine that maps spatial and temporal pH changes inside living cells. , 2009, Nature nanotechnology.

[80]  N. Harada,et al.  Light-driven monodirectional molecular rotor , 2022 .

[81]  Shantesh Hede,et al.  "Nano": the new nemesis of cancer. , 2006, Journal of cancer research and therapeutics.

[82]  J. O. Simpson,et al.  Ionic polymer-metal composites (IPMCs) as biomimetic sensors, actuators and artificial muscles - a review , 1998 .

[83]  G. Whitesides,et al.  Autonomous Movement and Self‐Assembly , 2002 .

[84]  Joseph M. DeSimone,et al.  Strategies in the design of nanoparticles for therapeutic applications , 2010, Nature Reviews Drug Discovery.

[85]  D. Velegol,et al.  Chemotaxis of nonbiological colloidal rods. , 2007, Physical review letters.

[86]  Yanyan Cao,et al.  Catalytic nanomotors: autonomous movement of striped nanorods. , 2004, Journal of the American Chemical Society.

[87]  J. Tour,et al.  Directional control in thermally driven single-molecule nanocars. , 2005, Nano letters.

[88]  Conor A. Bradley Drug delivery: DNA nanorobots — seek and destroy , 2018, Nature Reviews Drug Discovery.

[89]  A. Selçuklu,et al.  Treatment of severe intraventricular hemorrhage by intraventricular infusion of urokinase , 2004, Neurosurgical Review.

[90]  A. Lowman,et al.  Biodegradable nanoparticles for drug delivery and targeting , 2002 .

[91]  Ronald C. Chen,et al.  Revival of the abandoned therapeutic wortmannin by nanoparticle drug delivery , 2012, Proceedings of the National Academy of Sciences.

[92]  E. Purcell Life at Low Reynolds Number , 2008 .

[93]  Lichen Yin,et al.  Trimethyl Chitosan-Cysteine Nanoparticles for Systemic Delivery of TNF-α siRNA via Oral and Intraperitoneal Routes , 2013, Pharmaceutical Research.

[94]  Kristofer J. Thurecht,et al.  Nanoparticle-Based Medicines: A Review of FDA-Approved Materials and Clinical Trials to Date , 2016, Pharmaceutical Research.

[95]  Hooisweng Ow,et al.  Bright and stable core-shell fluorescent silica nanoparticles. , 2005, Nano letters.

[96]  Wei Wang,et al.  Autonomous motion of metallic microrods propelled by ultrasound. , 2012, ACS nano.

[97]  D. Clapham,et al.  Rheotaxis Guides Mammalian Sperm , 2013, Current Biology.

[98]  J. L. Davidson,et al.  Microfabricated systems and MEMS VII : proceedings of the international symposium , 2000 .

[99]  J T Hoff,et al.  Intracerebral infusion of thrombin as a cause of brain edema. , 1995, Journal of neurosurgery.

[100]  G. Nienhaus,et al.  Engineered nanoparticles interacting with cells: size matters , 2014, Journal of Nanobiotechnology.

[101]  P. K. Fung,et al.  A novel fabrication of ionic polymer-metal composites (IPMC) actuator with silver nano-powders , 2005, The 13th International Conference on Solid-State Sensors, Actuators and Microsystems, 2005. Digest of Technical Papers. TRANSDUCERS '05..

[102]  G. Wang,et al.  L-Carnitine-conjugated nanoparticles to promote permeation across blood–brain barrier and to target glioma cells for drug delivery via the novel organic cation/carnitine transporter OCTN2 , 2017, Artificial cells, nanomedicine, and biotechnology.