Mechanisms of mitophagy
暂无分享,去创建一个
[1] R. Youle,et al. Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin , 2010, The Journal of cell biology.
[2] A. Schapira,et al. Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy. , 2010, Human molecular genetics.
[3] Benedikt Westermann,et al. Mitochondrial fusion and fission in cell life and death , 2010, Nature Reviews Molecular Cell Biology.
[4] R. Youle,et al. p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both , 2010, Autophagy.
[5] S. Weber,et al. The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutations , 2010, Autophagy.
[6] Daniel J. Klionsky,et al. An Atg9-containing compartment that functions in the early steps of autophagosome biogenesis , 2010, The Journal of cell biology.
[7] D. Klionsky,et al. Eaten alive: a history of macroautophagy , 2010, Nature Cell Biology.
[8] D. Adams,et al. PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in Apc mutant mice , 2010, Proceedings of the National Academy of Sciences.
[9] Nobutaka Hattori,et al. p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria , 2010, Genes to cells : devoted to molecular & cellular mechanisms.
[10] D. Rubinsztein,et al. Plasma membrane contributes to the formation of pre-autophagosomal structures , 2010, Nature Cell Biology.
[11] G. Dorn,et al. Nix Is Critical to Two Distinct Phases of Mitophagy, Reactive Oxygen Species-mediated Autophagy Induction and Parkin-Ubiquitin-p62-mediated Mitochondrial Priming* , 2010, The Journal of Biological Chemistry.
[12] R. Youle,et al. Parkin overexpression selects against a deleterious mtDNA mutation in heteroplasmic cybrid cells , 2010, Proceedings of the National Academy of Sciences.
[13] K. Lim,et al. Disease-causing mutations in Parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy , 2010, The Journal of cell biology.
[14] D. Rubinsztein,et al. A comprehensive glossary of autophagy-related molecules and processes , 2010, Autophagy.
[15] Peter K. Kim,et al. Mitochondria Supply Membranes for Autophagosome Biogenesis during Starvation , 2010, Cell.
[16] N. Hattori,et al. PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy , 2010, The Journal of cell biology.
[17] Angela C. Poole,et al. The Mitochondrial Fusion-Promoting Factor Mitofusin Is a Substrate of the PINK1/Parkin Pathway , 2010, PloS one.
[18] F. Inagaki,et al. Atg8‐family interacting motif crucial for selective autophagy , 2010, FEBS letters.
[19] N. Hattori,et al. PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy , 2010, FEBS letters.
[20] A. Whitworth,et al. Drosophila Parkin requires PINK1 for mitochondrial translocation and ubiquitinates Mitofusin , 2010, Proceedings of the National Academy of Sciences.
[21] D. Klionsky,et al. A genomic screen for yeast mutants defective in mitophagy , 2010, Autophagy.
[22] Fabienne C. Fiesel,et al. PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1 , 2010, Nature Cell Biology.
[23] L. Chin,et al. Phosphorylation of parkin by Parkinson disease-linked kinase PINK1 activates parkin E3 ligase function and NF-kappaB signaling. , 2010, Human molecular genetics.
[24] Atsushi Tanaka,et al. PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin , 2010, PLoS biology.
[25] Ivan Dikic,et al. Nix is a selective autophagy receptor for mitochondrial clearance , 2010, EMBO reports.
[26] Ted M. Dawson,et al. PINK1-dependent recruitment of Parkin to mitochondria in mitophagy , 2009, Proceedings of the National Academy of Sciences.
[27] D. Ferguson,et al. Loss of autophagy in erythroid cells leads to defective removal of mitochondria and severe anemia in vivo , 2009, Proceedings of the National Academy of Sciences.
[28] Y. Ohsumi,et al. Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy. , 2009, Developmental cell.
[29] D. Klionsky,et al. Atg32 is a mitochondrial protein that confers selectivity during mitophagy. , 2009, Developmental cell.
[30] J. Cleveland,et al. Mitochondrial clearance is regulated by Atg7-dependent and -independent mechanisms during reticulocyte maturation. , 2009, Blood.
[31] Yoshiaki Kamada,et al. Dynamics and diversity in autophagy mechanisms: lessons from yeast , 2009, Nature Reviews Molecular Cell Biology.
[32] Y. Thielmann,et al. Nix directly binds to GABARAP: A possible crosstalk between apoptosis and autophagy , 2009, Autophagy.
[33] N. Hattori,et al. Parkin stabilizes PINK1 through direct interaction. , 2009, Biochemical and biophysical research communications.
[34] Gwang Lee,et al. Molecular interaction between parkin and PINK1 in mammalian neuronal cells , 2009, Molecular and Cellular Neuroscience.
[35] YongSung Kim,et al. PINK1 controls mitochondrial localization of Parkin through direct phosphorylation. , 2008, Biochemical and biophysical research communications.
[36] R. Youle,et al. Parkin is recruited selectively to impaired mitochondria and promotes their autophagy , 2008, The Journal of cell biology.
[37] Hansong Deng,et al. The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila , 2008, Proceedings of the National Academy of Sciences.
[38] Gareth Griffiths,et al. Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum , 2008, The Journal of cell biology.
[39] C. Thompson,et al. Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation. , 2008, Blood.
[40] H. Sandoval,et al. Essential role for Nix in autophagic maturation of erythroid cells , 2008, Nature.
[41] William Lin,et al. Characterization of PINK1 processing, stability, and subcellular localization , 2008, Journal of neurochemistry.
[42] M. Beal,et al. Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery , 2008, Proceedings of the National Academy of Sciences.
[43] Angela C. Poole,et al. The PINK1/Parkin pathway regulates mitochondrial morphology , 2008, Proceedings of the National Academy of Sciences.
[44] A. Schapira. Mitochondria in the aetiology and pathogenesis of Parkinson's disease , 2008, The Lancet Neurology.
[45] Min Wu,et al. Fission and selective fusion govern mitochondrial segregation and elimination by autophagy , 2008, The EMBO journal.
[46] D. Turnbull,et al. Nature of mitochondrial DNA deletions in substantia nigra neurons. , 2008, American journal of human genetics.
[47] J. Opferman,et al. NIX is required for programmed mitochondrial clearance during reticulocyte maturation , 2007, Proceedings of the National Academy of Sciences.
[48] G. Bjørkøy,et al. p62/SQSTM1 Binds Directly to Atg8/LC3 to Facilitate Degradation of Ubiquitinated Protein Aggregates by Autophagy* , 2007, Journal of Biological Chemistry.
[49] Y. Ohsumi,et al. Atg8, a Ubiquitin-like Protein Required for Autophagosome Formation, Mediates Membrane Tethering and Hemifusion , 2007, Cell.
[50] A. Pestronk,et al. Familial parkinsonism and ophthalmoplegia from a mutation in the mitochondrial DNA helicase twinkle. , 2007, Archives of neurology.
[51] S. Rodríguez-Enríquez,et al. Selective degradation of mitochondria by mitophagy. , 2007, Archives of biochemistry and biophysics.
[52] K. Nowikovsky,et al. Mdm38 protein depletion causes loss of mitochondrial K+/H+ exchange activity, osmotic swelling and mitophagy , 2007, Cell Death and Differentiation.
[53] Daniel J. Klionsky,et al. Aup1p, a Yeast Mitochondrial Protein Phosphatase Homolog, Is Required for Efficient Stationary Phase Mitophagy and Cell Survival* , 2007, Journal of Biological Chemistry.
[54] M. Beal,et al. Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[55] Sunhong Kim,et al. Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin , 2006, Nature.
[56] Changan Jiang,et al. Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin , 2006, Nature.
[57] C. Geula,et al. Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons , 2006, Nature Genetics.
[58] Robert W. Taylor,et al. High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease , 2006, Nature Genetics.
[59] C. Klein,et al. The genetics of Parkinson disease: implications for neurological care , 2006, Nature Clinical Practice Neurology.
[60] M. Gouy,et al. Phylogenomics of life-or-death switches in multicellular animals: Bcl-2, BH3-Only, and BNip families of apoptotic regulators. , 2005, Molecular biology and evolution.
[61] Stéphen Manon,et al. Uth1p Is Involved in the Autophagic Degradation of Mitochondria* , 2004, Journal of Biological Chemistry.
[62] L. Peltonen,et al. Parkinsonism, premature menopause, and mitochondrial DNA polymerase γ mutations: clinical and molecular genetic study , 2004, The Lancet.
[63] R. Nussbaum,et al. Hereditary Early-Onset Parkinson's Disease Caused by Mutations in PINK1 , 2004, Science.
[64] M. Raffeld,et al. The proapoptotic factor Nix is coexpressed with Bcl-xL during terminal erythroid differentiation. , 2003, Blood.
[65] C. Croce,et al. Parkin, a gene implicated in autosomal recessive juvenile parkinsonism, is a candidate tumor suppressor gene on chromosome 6q25–q27 , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[66] J. C. Greene,et al. Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[67] A. Tolkovsky,et al. Mitochondrial disappearance from cells: a clue to the role of autophagy in programmed cell death and disease? , 2002, Biochimie.
[68] S. Minoshima,et al. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism , 1998, Nature.
[69] T. Dawson,et al. The role of parkin in familial and sporadic Parkinson's disease , 2010, Movement disorders : official journal of the Movement Disorder Society.
[70] R. Roine,et al. A CLINICAL AND MOLECULAR GENETIC STUDY , 2010 .
[71] Y. Sakai,et al. Pexophagy in Pichia pastoris. , 2008, Methods in enzymology.
[72] C. Duve,et al. Functions of lysosomes. , 1966, Annual review of physiology.
[73] J. Lee,et al. Rhomboid-7 and HtrA 2 / Omi act in a common pathway with the Parkinson ’ s disease factors Pink 1 and Parkin , 2022 .