Discovery of (R)-(2-fluoro-4-((-4-methoxyphenyl)ethynyl)phenyl) (3-hydroxypiperidin-1-yl)methanone (ML337), an mGlu3 selective and CNS penetrant negative allosteric modulator (NAM).
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Julie L. Engers | Andrew S. Felts | Cody J. Wenthur | C. Lindsley | Frank W. Byers | Ryan Morrison | J. Daniels | K. Emmitte | P. J. Conn | Katrina A. Smith