Familial breast cancer.

Familial breast cancer is important because of all the known risk factors associated with developing the disease. The one with the most predictability is a positive family history. It is also important because a family history causes anxiety in the families concerned, and young women will often ask their chance of developing the disease. This form of breast cancer accounts for 10% of causes and has factors that distinguish it from the sporadic variety. Relatives of familial breast cancer patients are not only at an increased risk of developing the disease (if female) but also of developing other tumours especially colonic.

[1]  D. Anderson,et al.  A genetic study of human breast cancer. , 1972, Journal of the National Cancer Institute.

[2]  W. Kimberling,et al.  Natural history of hereditary cancer of the breast and colon , 1982, Cancer.

[3]  R. Elston,et al.  Genetic epidemiology of breast cancer and associated cancers in high-risk families. I. Segregation analysis. , 1983, Journal of the National Cancer Institute.

[4]  H. Lynch,et al.  Early age of onset in familial breast cancer. Genetic and cancer control implications. , 1976, Archives of surgery.

[5]  W. Kimberling,et al.  Breast cancer, genetics, and age at first pregnancy. , 1984, Journal of medical genetics.

[6]  S. Shapiro,et al.  Ten- to fourteen-year effect of screening on breast cancer mortality. , 1982, Journal of the National Cancer Institute.

[7]  M. J. Shear,et al.  Quantitative Experiments on the Production of Subcutaneous Tumors in Strain A Mice with Marginal Doses of 3, 4-Benzpyrene , 1943 .

[8]  D. Anderson,et al.  Some characteristics of familial breast cancer , 1971, Cancer.

[9]  R. Greenberg,et al.  Occurrence of Certain Multiple Primary Cancers in Females , 1969 .

[10]  R. Greenberg,et al.  Occurrence of certain multiple primary cancers in females. , 1968, Journal of the National Cancer Institute.

[11]  H T Lynch,et al.  Genetic factors in families with combined gastrointestinal and breast cancer. , 1973, The American journal of gastroenterology.

[12]  H. Lynch,et al.  Familial breast cancer: risk to the contralateral breast. , 1978, Journal of the National Cancer Institute.

[13]  L. Tabár,et al.  REDUCTION IN MORTALITY FROM BREAST CANCER AFTER MASS SCREENING WITH MAMMOGRAPHY Randomised Trial from the Breast Cancer Screening Working Group of the Swedish National Board of Health and Welfare , 1985, The Lancet.

[14]  M. King,et al.  Risk of breast cancer to relatives of young breast cancer patients. , 1985, Journal of the National Cancer Institute.