Genetic analysis of the human infective trypanosome Trypanosoma brucei gambiense: chromosomal segregation, crossing over, and the construction of a genetic map

[1]  P. Simarro,et al.  Eliminating Human African Trypanosomiasis: Where Do We Stand and What Comes Next> , 2008, PLoS medicine.

[2]  J. Boothroyd,et al.  Toxoplasma co-opts host gene expression by injection of a polymorphic kinase homologue , 2007, Nature.

[3]  J. Ajioka,et al.  Polymorphic Secreted Kinases Are Key Virulence Factors in Toxoplasmosis , 2006, Science.

[4]  Michael S. Behnke,et al.  A Secreted Serine-Threonine Kinase Determines Virulence in the Eukaryotic Pathogen Toxoplasma gondii , 2006, Science.

[5]  S. Melville,et al.  Hemizygous subtelomeres of an African trypanosome chromosome may account for over 75% of chromosome length. , 2006, Genome research.

[6]  N. Hall,et al.  The genetic map and comparative analysis with the physical map of Trypanosoma brucei , 2006, Nucleic Acids Research.

[7]  Human African trypanosomiasis (sleeping sickness): epidemiological update. , 2006, Releve epidemiologique hebdomadaire.

[8]  N. Hall,et al.  The genetic map and comparative analysis with the physical map of Trypanosoma brucei , 2005, Nucleic acids research.

[9]  A. MacLeod,et al.  Allelic segregation and independent assortment in T. brucei crosses: proof that the genetic system is Mendelian and involves meiosis. , 2005, Molecular and biochemical parasitology.

[10]  David M. A. Martin,et al.  The Genome of the African Trypanosome Trypanosoma brucei , 2005, Science.

[11]  Daniel Nilsson,et al.  Comparative Genomics of Trypanosomatid Parasitic Protozoa , 2005, Science.

[12]  Ian T. Paulsen,et al.  Composite genome map and recombination parameters derived from three archetypal lineages of Toxoplasma gondii , 2005, Nucleic acids research.

[13]  R. Carter,et al.  A genetic approach to the de novo identification of targets of strain-specific immunity in malaria parasites. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[14]  R. Carter,et al.  An AFLP-based genetic linkage map of Plasmodium chabaudi chabaudi , 2005, Malaria Journal.

[15]  A. MacLeod,et al.  Human infectivity trait in Trypanosoma brucei: stability, heritability and relationship to sra expression , 2004, Parasitology.

[16]  X. Su,et al.  Dissecting the loci of low‐level quinine resistance in malaria parasites , 2004, Molecular microbiology.

[17]  B. Barrell,et al.  The DNA sequence of chromosome I of an African trypanosome: gene content, chromosome organisation, recombination and polymorphism. , 2003, Nucleic acids research.

[18]  Steven Salzberg,et al.  The sequence and analysis of Trypanosoma brucei chromosome II. , 2003, Nucleic acids research.

[19]  J. Dubey,et al.  Identification of quantitative trait loci controlling acute virulence in Toxoplasma gondii , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[20]  S. Melville,et al.  Genetic analysis of phenotype in Trypanosoma brucei: a classical approach to potentially complex traits. , 2002, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[21]  K. Manly,et al.  Map Manager QTX, cross-platform software for genetic mapping , 2001, Mammalian Genome.

[22]  T. Petes,et al.  Meiotic recombination hot spots and cold spots , 2001, Nature Reviews Genetics.

[23]  S. Melville,et al.  The molecular karyotype of the megabase chromosomes of Trypanosoma brucei stock 427. , 2000, Molecular and biochemical parasitology.

[24]  J. T. Williams,et al.  Microsatellite markers reveal a spectrum of population structures in the malaria parasite Plasmodium falciparum. , 2000, Molecular biology and evolution.

[25]  M. Shirley,et al.  A genetic linkage map of the apicomplexan protozoan parasite Eimeria tenella. , 2000, Genome research.

[26]  J C Wootton,et al.  A genetic map and recombination parameters of the human malaria parasite Plasmodium falciparum. , 1999, Science.

[27]  A. MacLeod,et al.  A high level of mixed Trypanosoma brucei infections in tsetse flies detected by three hypervariable minisatellites. , 1999, Molecular and biochemical parasitology.

[28]  J. Stevens,et al.  Genetic exchange in the trypanosomatidae. , 1999, Advances in parasitology.

[29]  G. Benson,et al.  Tandem repeats finder: a program to analyze DNA sequences. , 1999, Nucleic acids research.

[30]  J. Blackwell,et al.  The molecular karyotype of the megabase chromosomes of Trypanosoma brucei and the assignment of chromosome markers. , 1998, Molecular and biochemical parasitology.

[31]  X. Su,et al.  Complex Polymorphisms in an ∼330 kDa Protein Are Linked to Chloroquine-Resistant P. falciparum in Southeast Asia and Africa , 1997, Cell.

[32]  X. Su,et al.  Complex polymorphisms in an approximately 330 kDa protein are linked to chloroquine-resistant P. falciparum in Southeast Asia and Africa. , 1997, Cell.

[33]  P. Wincker,et al.  Medium-range restriction maps of five chromosomes of Leishmania infantum and localization of size-variable regions. , 1996, Genomics.

[34]  P. Wincker,et al.  The Leishmania genome comprises 36 chromosomes conserved across widely divergent human pathogenic species. , 1996, Nucleic acids research.

[35]  C. Turner,et al.  Self-fertilisation in Trypanosoma brucei. , 1996, Molecular and biochemical parasitology.

[36]  A. Frasch,et al.  Chromosome specific markers reveal conserved linkage groups in spite of extensive chromosomal size variation in Trypanosoma cruzi. , 1995, Molecular and biochemical parasitology.

[37]  J. Ravetch,et al.  Organization of chromosomes in Plasmodium falciparum: a model for generating karyotypic diversity. , 1994, Parasitology today.

[38]  J. Ravetch,et al.  Transcriptional differences in polymorphic and conserved domains of a complete cloned P. falciparum chromosome , 1993, Nature.

[39]  C. Janse.  Chromosome size polymorphism and DNA rearrangements in plasmodium. , 1993, Parasitology today.

[40]  L. Sibley,et al.  Generation of a restriction fragment length polymorphism linkage map for Toxoplasma gondii. , 1992, Genetics.

[41]  L. V. D. van der Ploeg,et al.  Chromosome structure: DNA nucleotide sequence elements of a subset of the minichromosomes of the protozoan Trypanosoma brucei , 1991, Molecular and cellular biology.

[42]  P. Bastien,et al.  Long-range restriction maps of size-variable homologous chromosomes in Leishmania infantum. , 1991, Molecular and biochemical parasitology.

[43]  T. Wellems,et al.  Genetic mapping of the chloroquine-resistance locus on Plasmodium falciparum chromosome 7. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[44]  C. Turner,et al.  Evidence that the mechanism of gene exchange in Trypanosoma brucei involves meiosis and syngamy , 1990, Parasitology.

[45]  L. V. D. van der Ploeg,et al.  Chromosome organization of the protozoan Trypanosoma brucei , 1990, Molecular and cellular biology.

[46]  A. Tait,et al.  The identification of Trypanosoma brucei subspecies using repetitive DNA sequences. , 1990, Molecular and biochemical parasitology.

[47]  E. Pays,et al.  Different allele frequencies in Trypanosoma brucei brucei and Trypanosoma brucei gambiense populations. , 1989, Molecular and biochemical parasitology (Print).

[48]  D. Mccormick.  Sequence the Human Genome , 1986, Bio/Technology.

[49]  W. Gibson.  Will the real Trypanosoma b. gambiense please stand up. , 1986, Parasitology today.

[50]  J. Schweizer,et al.  Hybrid formation between African trypanosomes during cyclical transmission , 1986, Nature.

[51]  P. Borst,et al.  Chromosomes of kinetoplastida. , 1984, The EMBO journal.

[52]  P. Borst,et al.  Chromosome rearrangements in trypanosoma brucei , 1984, Cell.

[53]  John R. Young,et al.  Genomic environment of T. brucei VSG genes: presence of a minichromosome , 1982, Nature.

[54]  B. S. Baker,et al.  The genetic control of meiosis. , 1976, Annual review of genetics.