A direct comparison of tumor angiogenesis with 68Ga-labeled NGR and RGD peptides in HT-1080 tumor xenografts using microPET imaging

[1]  A. M. Moro,et al.  Radiolabeled NGR phage display peptide sequence for tumor targeting. , 2014, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

[2]  Zi-chun Hua,et al.  68Ga-DOTA-NGR as a novel molecular probe for APN-positive tumor imaging using MicroPET. , 2014, Nuclear medicine and biology.

[3]  A. David,et al.  Complexation of Cell-Penetrating Peptide–Polymer Conjugates with Polyanions Controls Cells Uptake of HPMA Copolymers and Anti-tumor Activity , 2013, Pharmaceutical Research.

[4]  K. Bhakoo,et al.  Stratification of 18F-Labeled PET Imaging Agents for the Assessment of Antiangiogenic Therapy Responses in Tumors , 2013, The Journal of Nuclear Medicine.

[5]  Markus Rudin,et al.  Barriers to Clinical Translation with Diagnostic Drugs , 2013, The Journal of Nuclear Medicine.

[6]  P. Conti,et al.  Synthesis and evaluation of 64Cu-labeled monomeric and dimeric NGR peptides for MicroPET imaging of CD13 receptor expression. , 2013, Molecular pharmaceutics.

[7]  Yingqi Zhang,et al.  99mTc-labeled monomeric and dimeric NGR peptides for SPECT imaging of CD13 receptor in tumor-bearing mice , 2012, Amino Acids.

[8]  A. Paradiso,et al.  Tumor endothelial markers as a target in cancer , 2012, Expert opinion on therapeutic targets.

[9]  K. Kaur,et al.  NGR peptide ligands for targeting CD13/APN identified through peptide array screening resemble fibronectin sequences. , 2012, ACS combinatorial science.

[10]  Z. Hua,et al.  Modification of Cyclic NGR Tumor Neovasculature-Homing Motif Sequence to Human Plasminogen Kringle 5 Improves Inhibition of Tumor Growth , 2012, PloS one.

[11]  Fan Wang,et al.  99mTc-labeled RGD-BBN peptide for small-animal SPECT/CT of lung carcinoma. , 2012, Molecular pharmaceutics.

[12]  Charles J. Smith,et al.  Radiotracers for different angiogenesis receptors in a melanoma model , 2012, Melanoma research.

[13]  Rongsheng E. Wang,et al.  Development of NGR-based anti-cancer agents for targeted therapeutics and imaging. , 2012, Anti-cancer agents in medicinal chemistry.

[14]  P. Riss,et al.  A methodical 68Ga-labelling study of DO2A-(butyl-L-tyrosine)2 with cation-exchanger post-processed 68Ga: practical aspects of radiolabelling. , 2011, Contrast media & molecular imaging.

[15]  S. W. Kim,et al.  Active targeting of RGD-conjugated bioreducible polymer for delivery of oncolytic adenovirus expressing shRNA against IL-8 mRNA. , 2011, Biomaterials.

[16]  J. Correia,et al.  Radiometallated peptides for molecular imaging and targeted therapy. , 2011, Dalton transactions.

[17]  Jason S. Lewis,et al.  A practical guide to the construction of radiometallated bioconjugates for positron emission tomography. , 2011, Dalton transactions.

[18]  R. Larsson,et al.  Aminopeptidase N (CD13) as a target for cancer chemotherapy , 2011, Cancer science.

[19]  P. Riss,et al.  The renaissance of the ⁶⁸Ge/⁶⁸Ga radionuclide generator initiates new developments in ⁶⁸Ga radiopharmaceutical chemistry. , 2010, Current topics in medicinal chemistry.

[20]  Goutham Reddy,et al.  Synthesis and in vitro evaluation of cyclic NGR peptide targeted thermally sensitive liposome. , 2010, Journal of controlled release : official journal of the Controlled Release Society.

[21]  P. Riss,et al.  The Renaissance of the 68 Ge / 68 Ga Radionuclide Generator Initiates New Developments in 68 Ga Radiopharmaceutical Chemistry , 2010 .

[22]  M. Schwaiger,et al.  Imaging of integrin alpha(v)beta(3) expression in patients with malignant glioma by [18F] Galacto-RGD positron emission tomography. , 2009, Neuro-oncology.

[23]  Dushyant V. Sahani,et al.  Biomarkers of response and resistance to antiangiogenic therapy , 2009, Nature Reviews Clinical Oncology.

[24]  Fan Wang,et al.  68Ga-labeled cyclic RGD dimers with Gly3 and PEG4 linkers: promising agents for tumor integrin αvβ3 PET imaging , 2009, European Journal of Nuclear Medicine and Molecular Imaging.

[25]  R. Schibli,et al.  Influence of the molecular charge on the biodistribution of bombesin analogues labeled with the [99mTc(CO)3]-core. , 2008, Bioconjugate chemistry.

[26]  Markus Schwaiger,et al.  Imaging of integrin αvβ3 expression , 2008, Cancer and Metastasis Reviews.

[27]  Katsunori Tanaka,et al.  PET (positron emission tomography) imaging of biomolecules using metal-DOTA complexes: a new collaborative challenge by chemists, biologists, and physicians for future diagnostics and exploration of in vivo dynamics. , 2008, Organic & biomolecular chemistry.

[28]  M. Schwaiger,et al.  Comparison of Integrin αvβ3 Expression and Glucose Metabolism in Primary and Metastatic Lesions in Cancer Patients: A PET Study Using 18F-Galacto-RGD and 18F-FDG , 2007, Journal of Nuclear Medicine.

[29]  Xiaoyuan Chen,et al.  68Ga-labeled multimeric RGD peptides for microPET imaging of integrin αvβ3 expression , 2008, European Journal of Nuclear Medicine and Molecular Imaging.

[30]  W. Oyen,et al.  Effects of linker variation on the in vitro and in vivo characteristics of an 111In-labeled RGD peptide. , 2007, Nuclear medicine and biology.

[31]  T. Quinn,et al.  Reducing renal uptake of 90Y- and 177Lu-labeled alpha-melanocyte stimulating hormone peptide analogues. , 2006, Nuclear medicine and biology.

[32]  Horst Kessler,et al.  Noninvasive Visualization of the Activated αvβ3 Integrin in Cancer Patients by Positron Emission Tomography and [18F]Galacto-RGD , 2005, PLoS medicine.

[33]  E. W. Meijer,et al.  Design and synthesis of a bimodal target-specific contrast agent for angiogenesis. , 2004, Organic letters.

[34]  W. Arap,et al.  CD13/APN is activated by angiogenic signals and is essential for capillary tube formation. , 2001, Blood.

[35]  P. Carmeliet,et al.  Angiogenesis in cancer and other diseases , 2000, Nature.

[36]  R Pasqualini,et al.  Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis. , 2000, Cancer research.

[37]  E. Ruoslahti,et al.  Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model. , 1998, Science.

[38]  R Pasqualini,et al.  A peptide isolated from phage display libraries is a structural and functional mimic of an RGD-binding site on integrins , 1995, The Journal of cell biology.

[39]  D. Parker.  Tumour Targeting with Radiolabelled Macrocycle-Antibody Conjugates , 1991 .

[40]  D. Parker.  Tumour targeting with radiolabelled macrocycle–antibody conjugates , 1990 .

[41]  C. Mogensen,et al.  Studies on renal tubular protein reabsorption: partial and near complete inhibition by certain amino acids. , 1977, Scandinavian journal of clinical and laboratory investigation.