Trends and challenges in modeling glioma using 3D human brain organoids
暂无分享,去创建一个
[1] Jay Gopalakrishnan,et al. SARS‐CoV‐2 targets neurons of 3D human brain organoids , 2020, The EMBO journal.
[2] Howon Lee,et al. Rapid Processing and Drug Evaluation in Glioblastoma Patient-Derived Organoid Models with 4D Bioprinted Arrays , 2020, iScience.
[3] J. Knoblich,et al. Human organoids: model systems for human biology and medicine , 2020, Nature Reviews Molecular Cell Biology.
[4] L. Ricci-Vitiani,et al. Rapid and Efficient Invasion Assay of Glioblastoma in Human Brain Organoids. , 2020, Cell reports.
[5] E. Gabriel,et al. Human Brain Organoids to Decode Mechanisms of Microcephaly , 2020, Frontiers in Cellular Neuroscience.
[6] A. Feuchtinger,et al. The Intratumoral Heterogeneity Reflects the Intertumoral Subtypes of Glioblastoma Multiforme: A Regional Immunohistochemistry Analysis , 2020, Frontiers in Oncology.
[7] R. Azzarelli. Organoid Models of Glioblastoma to Study Brain Tumor Stem Cells , 2020, Frontiers in Cell and Developmental Biology.
[8] M. Tartaglia,et al. Modeling medulloblastoma in vivo and with human cerebellar organoids , 2020, Nature Communications.
[9] H. Clevers,et al. Human Organoids: Tools for Understanding Biology and Treating Diseases. , 2020, Annual review of pathology.
[10] Zev A. Binder,et al. A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity , 2019, Cell.
[11] S. Pașca,et al. Organoid and Assembloid Technologies for Investigating Cellular Crosstalk in Human Brain Development and Disease. , 2019, Trends in cell biology.
[12] Max A. Horlbeck,et al. CRISPRi-based radiation modifier screen identifies long non-coding RNA therapeutic targets in glioma , 2019, Genome Biology.
[13] Jeffrey H. Chuang,et al. LONGITUDINAL MOLECULAR TRAJECTORIES OF DIFFUSE GLIOMA IN ADULTS , 2019, Nature.
[14] F. Hyder,et al. Development of human brain organoids with functional vascular-like system , 2019, Nature Methods.
[15] A. Brand,et al. Neural stem cell dynamics: the development of brain tumours. , 2019, Current opinion in cell biology.
[16] X. Breakefield,et al. Glioblastoma-Associated Microglia Reprogramming Is Mediated by Functional Transfer of Extracellular miR-21 , 2019, Cell reports.
[17] Shawn M. Gillespie,et al. Electrical and synaptic integration of glioma into neural circuits , 2019, Nature.
[18] Mariella G. Filbin,et al. An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma , 2019, Cell.
[19] J. Gopalakrishnan. The Emergence of Stem Cell‐Based Brain Organoids: Trends and Challenges , 2019, BioEssays : news and reviews in molecular, cellular and developmental biology.
[20] Sean K. Simmons,et al. Individual brain organoids reproducibly form cell diversity of the human cerebral cortex , 2019, Nature.
[21] F. Svensson,et al. Therapy for glioblastoma: is it working? , 2019, Drug discovery today.
[22] Gabriele Schackert,et al. Evolutionary Trajectories of IDHWT Glioblastomas Reveal a Common Path of Early Tumorigenesis Instigated Years ahead of Initial Diagnosis. , 2019, Cancer cell.
[23] S. Paek,et al. A bioprinted human-glioblastoma-on-a-chip for the identification of patient-specific responses to chemoradiotherapy , 2019, Nature Biomedical Engineering.
[24] H. Fine,et al. Modeling Patient-Derived Glioblastoma with Cerebral Organoids. , 2019, Cell reports.
[25] Giles W. Robinson,et al. Challenges to curing primary brain tumours , 2019, Nature Reviews Clinical Oncology.
[26] R. Kahn,et al. Microglia innately develop within cerebral organoids , 2018, Nature Communications.
[27] S. Sloan,et al. Generation and assembly of human brain region–specific three-dimensional cultures , 2018, Nature Protocols.
[28] J. Bagley,et al. Genetically engineered cerebral organoids model brain tumour formation , 2018, Nature Methods.
[29] A. Philpott,et al. The developmental origin of brain tumours: a cellular and molecular framework , 2018, Development.
[30] Inder M Verma,et al. Glioblastoma Model Using Human Cerebral Organoids , 2018, Cell reports.
[31] G. Govindaiah,et al. Fusion of Regionally Specified hPSC-Derived Organoids Models Human Brain Development and Interneuron Migration. , 2017, Cell stem cell.
[32] A. Olivi,et al. The clinical value of patient-derived glioblastoma tumorspheres in predicting treatment response , 2017, Neuro-oncology.
[33] D. Sher,et al. Radiation plus Temozolomide in Patients with Glioblastoma. , 2017, The New England journal of medicine.
[34] Madeline A. Lancaster,et al. Self‐organized developmental patterning and differentiation in cerebral organoids , 2017, The EMBO journal.
[35] Jonathan A. Bernstein,et al. Assembly of functionally integrated human forebrain spheroids , 2017, Nature.
[36] Daniel R. Berger,et al. Cell diversity and network dynamics in photosensitive human brain organoids , 2017, Nature.
[37] E. Gabriel,et al. Generation of iPSC-derived Human Brain Organoids to Model Early Neurodevelopmental Disorders. , 2017, Journal of visualized experiments : JoVE.
[38] Milos Nikolic,et al. Recent Zika Virus Isolates Induce Premature Differentiation of Neural Progenitors in Human Brain Organoids. , 2017, Cell stem cell.
[39] L. Parada,et al. Cell of Origin and Cancer Stem Cells in Tumor Suppressor Mouse Models of Glioblastoma , 2016, Cold Spring Harbor symposia on quantitative biology.
[40] Daniel R Weinberger,et al. Midbrain-like Organoids from Human Pluripotent Stem Cells Contain Functional Dopaminergic and Neuromelanin-Producing Neurons. , 2016, Cell stem cell.
[41] David W. Nauen,et al. Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure , 2016, Cell.
[42] Qiulian Wu,et al. A Three-Dimensional Organoid Culture System Derived from Human Glioblastomas Recapitulates the Hypoxic Gradients and Cancer Stem Cell Heterogeneity of Tumors Found In Vivo. , 2016, Cancer research.
[43] A. Hyman,et al. CPAP promotes timely cilium disassembly to maintain neural progenitor pool , 2016, The EMBO journal.
[44] Steven J. M. Jones,et al. Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma , 2016, Cell.
[45] Helmut Kettenmann,et al. The role of microglia and macrophages in glioma maintenance and progression , 2015, Nature Neuroscience.
[46] Voichita D. Marinescu,et al. The Human Glioblastoma Cell Culture Resource: Validated Cell Models Representing All Molecular Subtypes , 2015, EBioMedicine.
[47] D. Geschwind,et al. Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture , 2015, Nature Methods.
[48] Parag Mallick,et al. Neuronal Activity Promotes Glioma Growth through Neuroligin-3 Secretion , 2015, Cell.
[49] M. Eiraku,et al. Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell–derived neocortex , 2013, Proceedings of the National Academy of Sciences.
[50] V. P. Collins,et al. Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics , 2013, Proceedings of the National Academy of Sciences.
[51] H. Woo,et al. Patient-specific orthotopic glioblastoma xenograft models recapitulate the histopathology and biology of human glioblastomas in situ. , 2013, Cell reports.
[52] Tamas L. Horvath,et al. Modeling human cortical development in vitro using induced pluripotent stem cells , 2012, Proceedings of the National Academy of Sciences.
[53] P. A. Futreal,et al. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. , 2012, The New England journal of medicine.
[54] S. Ansari,et al. Isolation and expansion of human glioblastoma multiforme tumor cells using the neurosphere assay. , 2011, Journal of visualized experiments : JoVE.
[55] I. Date,et al. Angiogenesis and invasion in glioma , 2011, Brain Tumor Pathology.
[56] M. Tate,et al. Biology of angiogenesis and invasion in glioma , 2009, Neurotherapeutics.
[57] Mark Bernstein,et al. Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens. , 2009, Cell stem cell.
[58] Yoshiki Sasai,et al. Self-organized formation of polarized cortical tissues from ESCs and its active manipulation by extrinsic signals. , 2008, Cell stem cell.
[59] J. Xuereb,et al. High grade glioma: imaging combined with pathological grade defines management and predicts prognosis. , 2007, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.
[60] L. Chin,et al. Malignant astrocytic glioma: genetics, biology, and paths to treatment. , 2007, Genes & development.
[61] Martin J. van den Bent,et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. , 2005, The New England journal of medicine.
[62] R. Henkelman,et al. Identification of human brain tumour initiating cells , 2004, Nature.
[63] F. DiMeco,et al. Erratum: Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma (Cancer Research (October 2004) 64 (7011-7021) , 2004 .
[64] Ugo Orfanelli,et al. Isolation and Characterization of Tumorigenic, Stem-like Neural Precursors from Human Glioblastoma , 2004, Cancer Research.
[65] Jan C Buckner,et al. Factors influencing survival in high-grade gliomas. , 2003, Seminars in oncology.
[66] J. Holtfreter. Neural differentiation of ectoderm through exposure to saline solution , 1944 .
[67] R. G. Harrison,et al. Observations on the living developing nerve fiber , 1906 .
[68] H. Weishaupt,et al. Deregulated proliferation and differentiation in brain tumors , 2014, Cell and Tissue Research.