Cation-pi interactions in ligand recognition and catalysis.
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[1] E. Hulme,et al. Alanine-scanning mutagenesis of transmembrane domain 6 of the M(1) muscarinic acetylcholine receptor suggests that Tyr381 plays key roles in receptor function. , 1999, Molecular pharmacology.
[2] C. Higgins,et al. Molecular basis of multidrug transport by ATP-binding cassette transporters: a proposed two-cylinder engine model. , 2001, Journal of molecular microbiology and biotechnology.
[3] A. Gingras,et al. Cocrystal Structure of the Messenger RNA 5′ Cap-Binding Protein (eIF4E) Bound to 7-methyl-GDP , 1997, Cell.
[4] A. Gingras,et al. Structure of translation factor elF4E bound to m7GDP and interaction with 4E-binding protein , 1997, Nature Structural Biology.
[5] D. A. Dougherty,et al. Cation-π interactions in structural biology , 1999 .
[6] M. Schenone,et al. Structure and binding determinants of the recombinant kringle-2 domain of human plasminogen to an internal peptide from a group A Streptococcal surface protein. , 2001, Journal of molecular biology.
[7] Zhengliang L. Wu,et al. Farnesyl protein transferase: Identification of K164α and Y300β as catalytic residues by mutagenesis and kinetic studies , 1999 .
[8] E. Gouaux,et al. Mechanisms for Activation and Antagonism of an AMPA-Sensitive Glutamate Receptor Crystal Structures of the GluR2 Ligand Binding Core , 2000, Neuron.
[9] J. Pin,et al. Three‐dimensional model of the extracellular domain of the type 4a metabotropic glutamate receptor: New insights into the activation process , 2000, Protein science : a publication of the Protein Society.
[10] J. Leite,et al. Structure of Ligand-Gated Ion Channels: Critical Assessment of Biochemical Data Supports Novel Topology , 2001, Molecular and Cellular Neuroscience.
[11] J. Noel,et al. Structural basis for cyclic terpene biosynthesis by tobacco 5-epi-aristolochene synthase. , 1997, Science.
[12] A. Tulinsky,et al. Structure of tick anticoagulant peptide at 1.6 Å resolution complexed with bovine pancreatic trypsin inhibitor , 2008, Protein science : a publication of the Protein Society.
[13] D. Ragsdale,et al. A molecular basis for the different local anesthetic affinities of resting versus open and inactivated states of the sodium channel. , 1999, Molecular pharmacology.
[14] I. Mian,et al. Structure, function and properties of antibody binding sites. , 1991, Journal of molecular biology.
[15] H. Arias,et al. Topology of ligand binding sites on the nicotinic acetylcholine receptor , 1997, Brain Research Reviews.
[16] Yan Zhang,et al. Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses , 2001, Nature.
[17] T. Inagami,et al. A review of mutagenesis studies of angiotensin II type 1 receptor, the three‐dimensional receptor model in search of the agonist and antagonist binding site and the hypothesis of a receptor activation mechanism , 1997, Journal of hypertension.
[18] B. Biton,et al. Transmembrane Domain III Plays an Important Role in Ion Binding and Permeation in the Glycine Transporter GLYT2* , 2000, The Journal of Biological Chemistry.
[19] P. Schultz,et al. A MODEL FOR HYDRIDE TRANSFER IN THYMIDYLATE SYNTHASE BASED ON UNNATURAL AMINO ACID MUTAGENESIS , 1999 .
[20] B. Golinelli‐Pimpaneau,et al. Structural evidence for a programmed general base in the active site of a catalytic antibody. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[21] C. Deber,et al. Transmembrane aromatic amino acid distribution in P-glycoprotein. A functional role in broad substrate specificity. , 1994, Journal of molecular biology.
[22] T. Tansey,et al. Squalene synthase: structure and regulation. , 2001, Progress in nucleic acid research and molecular biology.
[23] D. A. Dougherty,et al. From ab initio quantum mechanics to molecular neurobiology: a cation-pi binding site in the nicotinic receptor. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[24] M. Hodel,et al. Structural requirements for the specific recognition of an m7G mRNA cap. , 2000, Biochemistry.
[25] M. Putman,et al. Molecular Properties of Bacterial Multidrug Transporters , 2000, Microbiology and Molecular Biology Reviews.
[26] C. Chang,et al. Unexpected binding mode of tick anticoagulant peptide complexed to bovine factor Xa. , 1998, Journal of molecular biology.
[27] J. Gallivan,et al. A Computational Study of Cation−π Interactions vs Salt Bridges in Aqueous Media: Implications for Protein Engineering , 2000 .
[28] H. Takeuchi,et al. Protonation of histidine and histidine-tryptophan interaction in the activation of the M2 ion channel from influenza a virus. , 2001, Biochemistry.
[29] Ziwei Huang,et al. Identification of the CD8 DE Loop as a Surface Functional Epitope , 1998, The Journal of Biological Chemistry.
[30] Cynthia Czajkowski,et al. Mapping the Agonist Binding Site of the GABAAReceptor: Evidence for a β-Strand , 1999, The Journal of Neuroscience.
[31] T. Sixma,et al. Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors , 2001, Nature.
[32] D. A. Dougherty,et al. Cation-π Interactions in Chemistry and Biology: A New View of Benzene, Phe, Tyr, and Trp , 1996, Science.
[33] D. Christianson,et al. Detoxification of environmental mutagens and carcinogens: structure, mechanism, and evolution of liver epoxide hydrolase. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[34] D. Stuart,et al. Crystal structure of the complex between human CD8αα and HLA-A2 , 1997, Nature.
[35] G. Gokel,et al. Experimental Evidence for Alkali Metal Cation−π Interactions , 2000 .
[36] G. Uhl,et al. Dopamine transporter tryptophan mutants highlight candidate dopamine- and cocaine-selective domains. , 2000, Molecular pharmacology.
[37] G R Marshall,et al. Light-activated rhodopsin induces structural binding motif in G protein alpha subunit. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[38] G. Verdine,et al. Structural Basis for the Excision Repair of Alkylation-Damaged DNA , 1996, Cell.
[39] D. Nurizzo,et al. Crystal structures and iron release properties of mutants (K206A and K296A) that abolish the dilysine interaction in the N-lobe of human transferrin. , 2001, Biochemistry.
[40] J Abelson,et al. Crystal structure of a dimeric archaeal splicing endonuclease. , 2000, Journal of molecular biology.
[41] J. Ballesteros,et al. A cluster of aromatic residues in the sixth membrane-spanning segment of the dopamine D2 receptor is accessible in the binding-site crevice. , 1998, Biochemistry.
[42] T. Koyama,et al. Enzymatic Aspects of Isoprenoid Chain Elongation. , 1998, Chemical reviews.
[43] M. Kavanaugh,et al. Tyrosine 140 of the γ-Aminobutyric Acid Transporter GAT-1 Plays a Critical Role in Neurotransmitter Recognition* , 1997, The Journal of Biological Chemistry.
[44] Y. Ru,et al. Rational design and synthesis of novel, potent bis-phenylamidine carboxylate factor Xa inhibitors. , 1998, Journal of medicinal chemistry.
[45] P. Y. Um,et al. Structure-function studies of human deoxyhypusine synthase: identification of amino acid residues critical for the binding of spermidine and NAD. , 2001, The Biochemical journal.
[46] T. Sixma,et al. A glia-derived acetylcholine-binding protein that modulates synaptic transmission , 2001, Nature.
[47] D. A. Dougherty,et al. The Cationminus signpi Interaction. , 1997, Chemical reviews.
[48] D. Guédin,et al. Molecular modeling of the GABA/GABA(B) receptor complex. , 2001, Journal of medicinal chemistry.
[49] K. Ihara,et al. Three-Dimensional Structure of a DNA Repair Enzyme, 3-Methyladenine DNA Glycosylase II, from Escherichia coli , 1996, Cell.
[50] M. Zhang,et al. The crystal structures of human α‐thrombin complexed with active site‐directed diamino benzo[b] thiophene derivatives: A binding mode for a structurally novel class of inhibitors , 2008, Protein science : a publication of the Protein Society.
[51] F A Quiocho,et al. mRNA cap recognition: dominant role of enhanced stacking interactions between methylated bases and protein aromatic side chains. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[52] C. Poulter,et al. Escherichia coli dimethylallyl diphosphate:tRNA dimethylallyltransferase: site-directed mutagenesis of highly conserved residues. , 2001, Biochemistry.
[53] P. Hergenrother,et al. Phosphatidylcholine-Preferring Phospholipase C from B. cereus. Function, Structure, and Mechanism , 2000 .
[54] G. Schulz,et al. Enzyme Mechanisms for Polycyclic Triterpene Formation. , 2000, Angewandte Chemie.
[55] S. Lummis,et al. The Role of Tryptophan Residues in the 5-Hydroxytryptamine3 Receptor Ligand Binding Domain* , 2000, The Journal of Biological Chemistry.
[56] M D Wyatt,et al. Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[57] T. Hoshino,et al. Functional analysis of phenylalanine 365 in hopene synthase, a conserved amino acid in the families of squalene and oxidosqualene cyclases† , 1999 .
[58] M. Hediger,et al. Functional roles of histidine and tyrosine residues in the H(+)-peptide transporter PepT1. , 2000, Biochemical and biophysical research communications.
[59] D. Cane,et al. Crystal structure of pentalenene synthase: mechanistic insights on terpenoid cyclization reactions in biology. , 1997, Science.
[60] J. Kroon,et al. Possible ligand-receptor interactions for NK1 antagonists as observed in their crystal structures. , 1997, Bioorganic & medicinal chemistry.
[61] S. Nakanishi,et al. Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor , 2000, Nature.
[62] V. L. Rath,et al. Human liver glycogen phosphorylase inhibitors bind at a new allosteric site. , 2000, Chemistry & biology.
[63] I. Paulsen,et al. Molecular characterization of the staphylococcal multidrug resistance export protein QacC , 1995, Journal of bacteriology.
[64] N S Scrutton,et al. Cation-pi bonding and amino-aromatic interactions in the biomolecular recognition of substituted ammonium ligands. , 1996, The Biochemical journal.
[65] A. Kuzin,et al. Substrate deformation in a hypoxanthine-guanine phosphoribosyltransferase ternary complex: the structural basis for catalysis. , 2000, Structure.
[66] B. Clantin,et al. Crystal structure of isopentenyl diphosphate:dimethylallyl diphosphate isomerase , 2001, The EMBO journal.
[67] F. Quiocho,et al. Structural basis of mRNA cap recognition by proteins. , 2000, Current opinion in structural biology.
[68] G. Schulz,et al. Structure and function of a squalene cyclase. , 1997, Science.
[69] T. Kwan,et al. Mutagenesis of transmembrane domain 11 of P-glycoprotein by alanine scanning. , 1996, Biochemistry.
[70] I. Shechter,et al. Function-Structure Studies and Identification of Three Enzyme Domains Involved in the Catalytic Activity in Rat Hepatic Squalene Synthase* , 1998, The Journal of Biological Chemistry.
[71] S. Schuldiner,et al. Mutations affecting substrate specificity of the Bacillus subtilis multidrug transporter Bmr , 1997, Journal of bacteriology.
[72] E. Keinan,et al. Chemically Reactive Immunogens Lead to Functional Convergence of the Immune Response , 2000 .
[73] S. Salvadori,et al. Opioid Diketopiperazines: Synthesis and Activity of a Prototypic Class of Opioid Antagonists , 1997, Biological chemistry.
[74] D. Barford,et al. Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B. , 2000, Molecular cell.