论文信息 - Speed-of-sound correction for photoacoustic and laser-ultrasound imaging with an integrating cylindrical detector

Speed-of-sound correction for photoacoustic and laser-ultrasound imaging with an integrating cylindrical detector

A method based on a modified inverse Radon transform is presented to correct photoacoustic and laser-ultrasound section images taken with a cylindrical integrating detector for heterogeneity in the speed of sound. Data for the correction are obtained with a laser ultrasound transmission method, providing two-dimensional maps of the speed of sound distribution. Photoacoustic, laser ultrasound and speed of sound tomography are combined in a single setup using illumination of the sample and several external absorbers with short pulses from a single laser source. The performance of the corrected reconstruction is compared in a simulation and a phantom experiment with a reconstruction using an average, constant sound speed. In this comparison, the reconstruction using the modified inverse Radon transform shows a small but distinguishable improvement.

[1] Martin Frenz,et al. Combined ultrasound and optoacoustic system for real-time high-contrast vascular imaging in vivo , 2005, IEEE Transactions on Medical Imaging.

[2] Markus Haltmeier,et al. Photoacoustic tomography using a Mach-Zehnder interferometer as an acoustic line detector. , 2007, Applied optics.

[3] Robert Nuster,et al. Hybrid photoacoustic and ultrasound section imaging with optical ultrasound detection , 2013, Journal of biophotonics.

[4] Günther Paltauf,et al. Combined photoacoustic and speed-of-sound imaging using integrating optical detection , 2014, Photonics West - Biomedical Optics.

[5] Robert Nuster,et al. Photoacoustic section imaging with an integrating cylindrical detector , 2011, Biomedical optics express.

[6] Guenther Paltauf,et al. Artifact removal in photoacoustic section imaging by combining an integrating cylindrical detector with model-based reconstruction , 2014, Journal of biomedical optics.

[7] Vasilis Ntziachristos,et al. Effects of small variations of speed of sound in optoacoustic tomographic imaging. , 2014, Medical physics.

[8] Wiendelt Steenbergen,et al. Speed-of-sound compensated photoacoustic tomography for accurate imaging. , 2012, Medical physics.

[9] W. Drexler,et al. Multimodal photoacoustic and optical coherence tomography scanner using an all optical detection scheme for 3D morphological skin imaging , 2011, Biomedical optics express.