Analysis, physiological and clinical significance of 12-HETE: a neglected platelet-derived 12-lipoxygenase product.

[1]  Cexiong Fu,et al.  Development of a high-throughput ultra performance liquid chromatography-mass spectrometry assay to profile 18 eicosanoids as exploratory biomarkers for atherosclerotic diseases. , 2013, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[2]  P. Mikuš,et al.  HPLC method for determination of lipoxygenase positional specific products. , 2013, Journal of pharmaceutical and biomedical analysis.

[3]  P. Le Faouder,et al.  LC-MS/MS method for rapid and concomitant quantification of pro-inflammatory and pro-resolving polyunsaturated fatty acid metabolites. , 2013, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[4]  J. Zugaza,et al.  ATP Antagonizes Thrombin-Induced Signal Transduction through 12(S)-HETE and cAMP , 2013, PLoS ONE.

[5]  H. Kuang,et al.  12(S)-hydroxyeicosatetraenoic acid levels link to coronary artery disease in Type 2 diabetic patients , 2013, Journal of Endocrinological Investigation.

[6]  Chris I. Jones,et al.  Transient heparin-induced platelet activation linked to generation of platelet 12-lipoxygenase , 2013, Thrombosis and Haemostasis.

[7]  W. Campbell,et al.  Endothelial 12(S)-HETE vasorelaxation is mediated by thromboxane receptor inhibition in mouse mesenteric arteries. , 2013, American journal of physiology. Heart and circulatory physiology.

[8]  T. Hankemeier,et al.  Quantitative profiling of oxylipins through comprehensive LC-MS/MS analysis: application in cardiac surgery , 2012, Analytical and Bioanalytical Chemistry.

[9]  G. Scherer,et al.  A simple and robust UPLC-SRM/MS method to quantify urinary eicosanoids , 2012, Journal of Lipid Research.

[10]  J. J. Moreno,et al.  Rapid simultaneous analysis of cyclooxygenase, lipoxygenase and cytochrome P-450 metabolites of arachidonic and linoleic acids using high performance liquid chromatography/mass spectrometry in tandem mode. , 2011, Journal of pharmaceutical and biomedical analysis.

[11]  Wenlian Zhang,et al.  Identification of the Orphan G Protein-coupled Receptor GPR31 as a Receptor for 12-(S)-Hydroxyeicosatetraenoic Acid* , 2011, The Journal of Biological Chemistry.

[12]  E. Chan,et al.  Ultra-pressure liquid chromatography/tandem mass spectrometry targeted profiling of arachidonic acid and eicosanoids in human colorectal cancer. , 2011, Rapid communications in mass spectrometry : RCM.

[13]  H. Hamm,et al.  Protease-Activated Receptor Signaling in Platelets Activates Cytosolic Phospholipase A2&agr; Differently for Cyclooxygenase-1 and 12-Lipoxygenase Catalysis , 2011, Arteriosclerosis, thrombosis, and vascular biology.

[14]  D. Nie,et al.  12-Lipoxygenase and the regulation of hypoxia-inducible factor in prostate cancer cells. , 2010, Experimental cell research.

[15]  A. Nalla,et al.  Targeting MMP-9, uPAR, and cathepsin B inhibits invasion, migration and activates apoptosis in prostate cancer cells , 2010, Cancer Gene Therapy.

[16]  J. Nadler,et al.  12-Lipoxygenase Products Reduce Insulin Secretion and {beta}-Cell Viability in Human Islets. , 2010, The Journal of clinical endocrinology and metabolism.

[17]  M. Margaglione,et al.  Setting up a 2D-LC/MS/MS method for the rapid quantitation of the prostanoid metabolites 6-oxo-PGF(1alpha) and TXB2 as markers for hemostasis assessment. , 2009, Journal of mass spectrometry : JMS.

[18]  K. Safranow,et al.  Platelets arachidonic acid metabolism in patients with essential hypertension , 2009, Platelets.

[19]  O. Boutaud,et al.  Acetylation of prostaglandin H2 synthases by aspirin is inhibited by redox cycling of the peroxidase. , 2008, Biochemical pharmacology.

[20]  A. Mir,et al.  Simultaneous lipidomic analysis of three families of bioactive lipid mediators leukotrienes, resolvins, protectins and related hydroxy-fatty acids by liquid chromatography/electrospray ionisation tandem mass spectrometry. , 2008, Rapid communications in mass spectrometry : RCM.

[21]  S. Karpatkin,et al.  Platelet particle formation by anti GPIIIa49-66 Ab, Ca2+ ionophore A23187, and phorbol myristate acetate is induced by reactive oxygen species and inhibited by dexamethasone blockade of platelet phospholipase A2, 12-lipoxygenase, and NADPH oxidase. , 2007, Blood.

[22]  M. Cattaneo.  Resistance to antiplatelet drugs: molecular mechanisms and laboratory detection , 2007, Journal of thrombosis and haemostasis : JTH.

[23]  D. Barrett,et al.  Quantitative profiling of epoxyeicosatrienoic, hydroxyeicosatetraenoic, and dihydroxyeicosatetraenoic acids in human intrauterine tissues using liquid chromatography/electrospray ionization tandem mass spectrometry. , 2007, Analytical biochemistry.

[24]  M. Barbe,et al.  A liquid chromatography/mass spectrometric method for simultaneous analysis of arachidonic acid and its endogenous eicosanoid metabolites prostaglandins, dihydroxyeicosatrienoic acids, hydroxyeicosatetraenoic acids, and epoxyeicosatrienoic acids in rat brain tissue. , 2007, Journal of pharmaceutical and biomedical analysis.

[25]  I. Shureiqi,et al.  Determination of endogenous tissue inflammation profiles by LC/MS/MS: COX- and LOX-derived bioactive lipids. , 2006, Prostaglandins, leukotrienes, and essential fatty acids.

[26]  D. Nie,et al.  Mechanisms Regulating Tumor Angiogenesis by 12-Lipoxygenase in Prostate Cancer Cells* , 2006, Journal of Biological Chemistry.

[27]  I. Wobst,et al.  Monitoring eicosanoid biosynthesis via lipoxygenase and cyclooxygenase pathways in human whole blood by single HPLC run. , 2006, Journal of pharmaceutical and biomedical analysis.

[28]  S. Selman,et al.  Vascular endothelial growth factor production in human prostate cancer cells is stimulated by overexpression of platelet 12‐lipoxygenase , 2006, The Prostate.

[29]  W. See,et al.  Elevated 12- and 20-hydroxyeicosatetraenoic acid in urine of patients with prostatic diseases. , 2006, Cancer letters.

[30]  R. Murphy,et al.  Electrospray ionization and tandem mass spectrometry of eicosanoids. , 2005, Analytical biochemistry.

[31]  Takao Shimizu,et al.  A multiplex quantitation method for eicosanoids and platelet-activating factor using column-switching reversed-phase liquid chromatography-tandem mass spectrometry. , 2005, Analytical biochemistry.

[32]  Valerie B O'Donnell,et al.  Platelet 12-Lipoxygenase Activation via Glycoprotein VI: Involvement of Multiple Signaling Pathways in Agonist Control of H(P)ETE Synthesis , 2004, Circulation research.

[33]  S. Karpatkin,et al.  Complement-independent Ab-induced peroxide lysis of platelets requires 12-lipoxygenase and a platelet NADPH oxidase pathway. , 2004, The Journal of clinical investigation.

[34]  R. DuBois,et al.  Targeted lipidomics using electron capture atmospheric pressure chemical ionization mass spectrometry. , 2003, Rapid communications in mass spectrometry : RCM.

[35]  M. Lagarde,et al.  Activation of p38 mitogen-activated protein kinase/cytosolic phospholipase A2 cascade in hydroperoxide-stressed platelets. , 2003, Free radical biology & medicine.

[36]  K. Honn,et al.  Overexpression of platelet-type 12-lipoxygenase promotes tumor cell survival by enhancing alpha(v)beta(3) and alpha(v)beta(5) integrin expression. , 2003, Cancer research.

[37]  R. Jensen,et al.  12-Lipoxygenase in Opioid-Induced Delayed Cardioprotection: Gene Array, Mass Spectrometric, and Pharmacological Analyses , 2003, Circulation research.

[38]  T. Hishinuma,et al.  Determination of urinary 12(S)-hydroxyeicosatetraenoic acid by liquid chromatography-tandem mass spectrometry with column-switching technique: sex difference in healthy volunteers and patients with diabetes mellitus. , 2003, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[39]  Hon-chi Lee,et al.  Arachidonic Acid-Induced Vasodilation of Rat Small Mesenteric Arteries Is Lipoxygenase-Dependent , 2003, Journal of Pharmacology and Experimental Therapeutics.

[40]  V. Sondak,et al.  Expression of 12-lipoxygenase as a biomarker for melanoma carcinogenesis , 2002, Melanoma research.

[41]  Yoshitaka Takahashi,et al.  Arachidonate 12-lipoxygenases. , 2002, Prostaglandins & other lipid mediators.

[42]  N. Kaiser,et al.  A natural protective mechanism against hyperglycaemia in vascular endothelial and smooth-muscle cells: role of glucose and 12-hydroxyeicosatetraenoic acid. , 2002, The Biochemical journal.

[43]  T. Adrian,et al.  12‐lipoxygenase metabolite 12(S)‐HETE stimulates human pancreatic cancer cell proliferation via protein tyrosine phosphorylation and ERK activation , 2001, International journal of cancer.

[44]  R. Newman,et al.  Simultaneous quantification of arachidonic acid metabolites in cultured tumor cells using high-performance liquid chromatography/electrospray ionization tandem mass spectrometry. , 2001, Analytical biochemistry.

[45]  S. Adler,et al.  12-lipoxygenase is increased in glucose-stimulated mesangial cells and in experimental diabetic nephropathy. , 2001, Kidney international.

[46]  J. Rossi,et al.  Ribozyme-Mediated Inhibition of Rat Leukocyte-Type 12-Lipoxygenase Prevents Intimal Hyperplasia in Balloon-Injured Rat Carotid Arteries , 2001, Circulation.

[47]  F. Rivera,et al.  Increased Levels of 12(S)-HETE in Patients With Essential Hypertension , 2001, Hypertension.

[48]  D. Nie,et al.  Eicosanoid Regulation of Angiogenesis in Human Prostate Carcinoma and Its Therapeutic Implications , 2000, Annals of the New York Academy of Sciences.

[49]  D. Nie,et al.  Eicosanoid regulation of angiogenesis: role of endothelial arachidonate 12-lipoxygenase. , 2000, Blood.

[50]  J. Bousquet,et al.  A method for the measurement of plasma hydroxyeicosatetraenoic acid levels. , 1999, Analytical biochemistry.

[51]  D. Rader,et al.  Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice. , 1999, The Journal of clinical investigation.

[52]  J. Maclouf,et al.  The relationship of hydroxyeicosatetraenoic acids and F2-isoprostanes to plaque instability in human carotid atherosclerosis. , 1999, The Journal of clinical investigation.

[53]  D. Tsikas,et al.  Application of gas chromatography-mass spectrometry and gas chromatography-tandem mass spectrometry to assess in vivo synthesis of prostaglandins, thromboxane, leukotrienes, isoprostanes and related compounds in humans. , 1998, Journal of chromatography. B, Biomedical sciences and applications.

[54]  R. Natarajan,et al.  Role of lipoxygenases in breast cancer. , 1998, Frontiers in bioscience : a journal and virtual library.

[55]  T. Barbui,et al.  Aspirin increases the bleeding side effects in essential thrombocythemia independent of the cyclooxygenase pathway: Role of the lipoxygenase pathway , 1998, American journal of hematology.

[56]  C. Funk,et al.  Increased platelet sensitivity to ADP in mice lacking platelet-type 12-lipoxygenase. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[57]  K. Watanabe,et al.  Decreased activity of arachidonate 12-lipoxygenase in platelets of Japanese patients with non-insulin-dependent diabetes mellitus. , 1998, Metabolism: clinical and experimental.

[58]  H. Imai,et al.  Suppression of Leukotriene Formation in RBL-2H3 Cells That Overexpressed Phospholipid Hydroperoxide Glutathione Peroxidase* , 1998, The Journal of Biological Chemistry.

[59]  A. Mallet,et al.  Rapid simultaneous analysis of prostaglandin E2, 12-hydroxyeicosatetraenoic acid and arachidonic acid using high performance liquid chromatography/electrospray ionization mass spectrometry. , 1997, Rapid communications in mass spectrometry : RCM.

[60]  M. Lagarde,et al.  Low concentrations of lipid hydroperoxides prime human platelet aggregation specifically via cyclo-oxygenase activation. , 1997, The Biochemical journal.

[61]  L. Lanting,et al.  Platelet‐derived growth factor BB mediated regulation of 12‐lipoxygenase in porcine aortic smooth muscle cells , 1996, Journal of Cellular Physiology.

[62]  M. Sasaki,et al.  Platelet lipoxygenase inhibitors attenuate thrombin- and thromboxane mimetic-induced intracellular calcium mobilization and platelet aggregation. , 1996, The Journal of pharmacology and experimental therapeutics.

[63]  E. Kisch,et al.  Platelet lipoxygenase in spontaneously hypertensive rats. , 1996, Hypertension.

[64]  R. Natarajan,et al.  A 12-lipoxygenase product, 12-hydroxyeicosatetraenoic acid, is increased in diabetics with incipient and early renal disease. , 1996, The Journal of clinical endocrinology and metabolism.

[65]  F. Ursini,et al.  The Selenoenzyme Phospholipid Hydroperoxide Glutathione Peroxidase Controls the Activity of the 15-Lipoxygenase with Complex Substrates and Preserves the Specificity of the Oxygenation Products (*) , 1996, The Journal of Biological Chemistry.

[66]  C. Brideau,et al.  A human whole blood assay for clinical evaluation of biochemical efficacy of cyclooxygenase inhibitors , 1996, Inflammation Research.

[67]  M. Mcdaniel,et al.  Interleukin-1 Enhances Pancreatic Islet Arachidonic Acid 12-Lipoxygenase Product Generation by Increasing Substrate Availability through a Nitric Oxide-dependent Mechanism (*) , 1996, The Journal of Biological Chemistry.

[68]  Y. Hannun,et al.  12(S)-hydroxyeicosatetraenoic acid and 13(S)-hydroxyoctadecadienoic acid regulation of protein kinase C-alpha in melanoma cells: role of receptor-mediated hydrolysis of inositol phospholipids. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[69]  J. Tímár,et al.  12-Lipoxygenases and 12(S)-HETE: role in cancer metastasis , 1994, Cancer and Metastasis Reviews.

[70]  P. Poubelle,et al.  Reverse-phase high-performance liquid chromatography analysis of arachidonic acid metabolites in plasma after stimulation of whole blood ex vivo. , 1994, Analytical biochemistry.

[71]  J. Tímár,et al.  Tumor cell-derived 12(S)-hydroxyeicosatetraenoic acid induces microvascular endothelial cell retraction. , 1994, Cancer research.

[72]  S. Yamamoto,et al.  Lipoxin synthase activity of human platelet 12-lipoxygenase. , 1993, The Biochemical journal.

[73]  J. Rossi,et al.  Elevated glucose and angiotensin II increase 12-lipoxygenase activity and expression in porcine aortic smooth muscle cells. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[74]  A. Wendel,et al.  Selenoenzymes regulate the activity of leukocyte 5-lipoxygenase via the peroxide tone. , 1993, The Journal of biological chemistry.

[75]  K. Honn,et al.  12(S)-HETE-induced microvascular endothelial cell retraction results from PKC-dependent rearrangement of cytoskeletal elements and αVβ3 integrins , 1993 .

[76]  W. Mathews,et al.  Quantitation of hydroperoxy-eicosatetraenoic acids and hydroxy-eicosatetraenoic acids as indicators of lipid peroxidation using gas chromatography-mass spectrometry. , 1993, Analytical biochemistry.

[77]  S. Yamamoto,et al.  Decreased messenger RNA of arachidonate 12-lipoxygenase in platelets of patients with myeloproliferative disorders. , 1993, Biochimica et biophysica acta.

[78]  D. Moller,et al.  Differential Regulation of Glucose Transport and Transporters by Glucose in Vascular Endothelial and Smooth Muscle Cells , 1993, Diabetes.

[79]  Y. Hannun,et al.  15-Hydroxyeicosatetraenoic acid-mediated potentiation of thrombin-induced platelet functions occurs via enhanced production of phosphoinositide-derived second messengers--sn-1,2-diacylglycerol and inositol-1,4,5-trisphosphate. , 1992, Blood.

[80]  C. Serhan,et al.  Lipoxin recognition sites. Specific binding of labeled lipoxin A4 with human neutrophils. , 1992, The Journal of biological chemistry.

[81]  R. Murphy,et al.  Quantitation of 20-hydroxy-5,8,11,14-eicosatetraenoic acid (20-HETE) produced by human polymorphonuclear leukocytes using electron capture ionization gas chromatography/mass spectrometry. , 1992, Biological mass spectrometry.

[82]  C. Piantadosi,et al.  Recovery of energy metabolism in rat brain after carbon monoxide hypoxia. , 1992, The Journal of clinical investigation.

[83]  J. Lindgren,et al.  Deficient lipoxin synthesis: a novel platelet dysfunction in myeloproliferative disorders with special reference to blastic crisis of chronic myelogenous leukemia. , 1991, Blood.

[84]  Y. Seyama,et al.  The differences in 12-hydroxyeicosatetraenoic acid and thromboxane B2 release from guinea pig platelets. , 1991, Prostaglandins.

[85]  J. Takagi,et al.  12S-hydroxyeicosatetraenoic acid plays a central role in the regulation of platelet activation. , 1991, Biochemical and biophysical research communications.

[86]  P. Fonlupt,et al.  12-HETE inhibits the binding of PGH2/TXA2 receptor ligands in human platelets. , 1991, Thrombosis research.

[87]  J. Takagi,et al.  Feedback regulation of platelet function by 12S-hydroxyeicosatetraenoic acid: inhibition of arachidonic acid liberation from phospholipids. , 1990, Biochimica et biophysica acta.

[88]  C. Serhan,et al.  Lipoxin formation during human neutrophil-platelet interactions. Evidence for the transformation of leukotriene A4 by platelet 12-lipoxygenase in vitro. , 1990, The Journal of clinical investigation.

[89]  E. Spiess,et al.  An in vitro model study of BSp73 rat tumour cell invasion into endothelial monolayer. , 1989, Anticancer research.

[90]  A. Hatzelmann,et al.  Involvement of glutathione peroxidase activity in the stimulation of 5-lipoxygenase activity by glutathione-depleting agents in human polymorphonuclear leukocytes. , 1989, European journal of biochemistry.

[91]  K. Kragballe,et al.  Eicosanoids in skin of patients with atopic dermatitis: prostaglandin E2 and leukotriene B4 are present in biologically active concentrations. , 1989, The Journal of allergy and clinical immunology.

[92]  B. Wolf,et al.  Quantitative stereochemical analysis of subnanogram amounts of 12-hydroxy-(5,8,10,14)-eicosatetraenoic acid by sequential chiral phase liquid chromatography and stable isotope dilution mass spectrometry. , 1988, Analytical biochemistry.

[93]  S. Sunderji,et al.  Formation of Hydroxyeicosatetraenoic Acids (HETE) in Blood From Adults Versus Neonates: Reduced Production of 12-HETE in Cord Blood , 1988, Pediatric Research.

[94]  Bonnie F. Sloane,et al.  Morphological study of the interaction of intravascular tumor cells with endothelial cells and subendothelial matrix. , 1988, Cancer research.

[95]  R. Natarajan,et al.  Specific action of the lipoxygenase pathway in mediating angiotensin II-induced aldosterone synthesis in isolated adrenal glomerulosa cells. , 1987, The Journal of clinical investigation.

[96]  J. Nadler,et al.  The inhibitory role of 12- and 15-lipoxygenase products on renin release. , 1987, Hypertension.

[97]  W. Powell.  Precolumn extraction and reversed-phase high-pressure liquid chromatography of prostaglandins and leukotrienes. , 1987, Analytical biochemistry.

[98]  H. Esterbauer,et al.  Quantitative measurement of 5-, 12-, and 15-hydroxyeicosatetraenoic acid together with 12-hydroxyheptadecatrienoic acid by stable isotope dilution gas chromatography-negative ion chemical ionization-mass spectrometry. , 1987, Analytical biochemistry.

[99]  M. Radomski,et al.  Salicylates and 12-lipoxygenase activity in human washed platelets. , 1986, Pharmacological research communications.

[100]  E. Tremoli,et al.  In vitro effects of aspirin and non steroidal anti-inflammatory drugs on the formation of 12-hydroxyeicosatetraenoic acid by platelets. , 1986, Prostaglandins, leukotrienes, and medicine.

[101]  P. Woollard.  Stereochemical difference between 12-hydroxy-5,8,10,14-eicosatetraenoic acid in platelets and psoriatic lesions. , 1986, Biochemical and biophysical research communications.

[102]  C. Sirtori,et al.  Platelet formation of 12-hydroxyeicosatetraenoic acid and thromboxane B2 is increased in type IIA hypercholesterolemic subjects. , 1986, Atherosclerosis.

[103]  J. Eskra,et al.  Solid-phase extraction and high-performance liquid chromatography analysis of lipoxygenase pathway products. , 1986, Analytical biochemistry.

[104]  T. Terano,et al.  Comparison of the in vitro effect of eicosapentaenoic acid (EPA)-derived lipoxygenase metabolites on human platelet function with those of arachidonic acid. , 1986, Thrombosis research.

[105]  P. Comens,et al.  Arachidonic acid metabolism in isolated pancreatic islets. IV. Negative ion-mass spectrometric quantitation of monooxygenase product synthesis by liver and islets. , 1985, Biochimica et biophysica acta.

[106]  J. Maclouf,et al.  Enzyme immunoassays of eicosanoids using acetylcholine esterase as label: an alternative to radioimmunoassay. , 1985, Analytical chemistry.

[107]  A. Kreft,et al.  Inhibition of platelet and neutrophil phospholipase A2 by hydroxyeicosatetraenoic acids (HETES). A novel pharmacological mechanism for regulating free fatty acid release. , 1985, Biochemical pharmacology.

[108]  E. Tremoli,et al.  Effects of PGI2 on platelet aggregation and adenylate cyclase activity in human type IIa hypercholesterolemia. , 1983, Biochemical pharmacology.

[109]  D. Caruso,et al.  Preferential utilization of endogenous arachidonate by cyclo‐oxygenase in incubations of human platelets , 1983, FEBS letters.

[110]  M. Lagarde,et al.  Stereospecific inhibition of PGH2-induced platelet aggregation by lipoxygenase products of icosaenoic acids. , 1983, Biochemical and biophysical research communications.

[111]  R. Bryant,et al.  Role of glutathione peroxidase and hexose monophosphate shunt in the platelet lipoxygenase pathway. , 1982, The Journal of biological chemistry.

[112]  D. Hwang.  Characteristics of the formation of the platelet lipoxygenase product from endogenous arachidonic acid , 1982, Lipids.

[113]  D. Aharony,et al.  Regulation of arachidonate-induced platelet aggregation by the lipoxygenase product, 12-hydroperoxyeicosatetraenoic acid. , 1982, Biochimica et biophysica acta.

[114]  J. Maclouf,et al.  Stimulation of leukotriene biosynthesis in human blood leukocytes by platelet-derived 12-hydroperoxy-icosatetraenoic acid. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[115]  M. Dunn,et al.  Lipoxygenase activity in rat kidney glomeruli, glomerular epithelial cells, and cortical tubules. , 1982, The Journal of biological chemistry.

[116]  S. Murota,et al.  Platelets stimulate aortic smooth muscle cell migration in vitro. Involvement of 12-L-hydroxy-5,8,10,14-eicosatetraenoic acid. , 1982, Atherosclerosis.

[117]  A. Schafer.  Deficiency of platelet lipoxygenase activity in myeloproliferative disorders. , 1982, The New England journal of medicine.

[118]  E. Corey,et al.  Radioimmunoassay of the leukotrienes of slow reacting substance of anaphylaxis. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[119]  S. Picard,et al.  Transformation of arachidonic acid in leukocytes. Isolation and structural analysis of a novel dihydroxy derivative. , 1981, Prostaglandins and medicine.

[120]  E. Goetzl,et al.  The development of a radioimmunoassay for 12-L-hydroxyeicosatetraenoic acid. , 1980, Prostaglandins.

[121]  W. Powell.  Distribution of prostaglandin ω-hydroxylases in different tissues , 1980 .

[122]  C. Patrono,et al.  Low dose aspirin and inhibition of thromboxane B2 production in healthy subjects. , 1980, Thrombosis research.

[123]  M. Okuma,et al.  Altered arachidonate metabolism by platelets in patients with myeloproliferative disorders. , 1979, Blood.

[124]  P. Cuatrecasas,et al.  Aspirin-like drugs interfere with arachidonate metabolism by inhibition of the 12-hydroperoxy-5,8,10,14-eicosatetraenoic acid peroxidase activity of the lipoxygenase pathway. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[125]  J. Hoak,et al.  Lipoproteins and the Inhibitory Effect of Human Endothelial Cells on Platelet Function , 1978, Circulation research.

[126]  J. Tainer,et al.  Biogenesis of chemotactic molecules by the arachidonate lipoxygenase system of platelets , 1975, Nature.

[127]  R. Colman,et al.  Clofibrate Reversal of Platelet Hypersensitivity in Hyperbetalipoproteinemia , 1974, Circulation.

[128]  R. Colman,et al.  Platelet function in hyperlipoproteinemia. , 1974, The New England journal of medicine.

[129]  J. Christman,et al.  Method development and validation for ultra-high pressure liquid chromatography/tandem mass spectrometry determination of multiple prostanoids in biological samples. , 2013, Journal of AOAC International.

[130]  E. Dennis,et al.  Detection and quantitation of eicosanoids via high performance liquid chromatography-electrospray ionization-mass spectrometry. , 2007, Methods in enzymology.

[131]  L. Liotta,et al.  Endothelialization of embolized tumor cells during metastasis formation , 2005, Clinical & Experimental Metastasis.

[132]  R. Natarajan,et al.  12-Lipoxygenase metabolism in mouse distal convoluted tubule cells. , 2005, Kidney international.

[133]  P. Shankaranarayanan,et al.  Evidence for the presence of phospholipid hydroperoxide glutathione peroxidase in human platelets: implications for its involvement in the regulatory network of the 12-lipoxygenase pathway of arachidonic acid metabolism. , 2001, The Biochemical journal.

[134]  K. Honn,et al.  12(S)-HETE in cancer metastasis. , 1999, Advances in experimental medicine and biology.

[135]  R. Reich,et al.  Role of lipoxygenase in the regulation of glucose transport in aortic vascular cells. , 1999, Advances in experimental medicine and biology.

[136]  K. Honn,et al.  Role of protein kinase C and phosphatases in 12(S)-HETE-induced tumor cell cytoskeletal reorganization. , 1997, Advances in experimental medicine and biology.

[137]  N. Stern,et al.  The lipoxygenase inhibitor phenidone is a potent hypotensive agent in the spontaneously hypertensive rat. , 1993, American journal of hypertension.

[138]  Chew Ec,et al.  In vitro studies on the invasion of blood vessel wall by choriocarcinoma cells. , 1989 .

[139]  E. Tremoli,et al.  Aspirin inhibits platelet 12-hydroxy-eicosatetraenoic acid formation. , 1986, The Journal of laboratory and clinical medicine.

[140]  E. Tremoli,et al.  Modifications of platelet functional and biochemical parameters in human type IIa hypercholesterolemia. , 1986, Agents and actions. Supplements.

[141]  W. Pickett,et al.  Automated extraction and HPLC resolution of lipoxygenase and cyclooxygenase products utilizing high pressure column switching. , 1985, Prostaglandins.