Defining the Teratoma as a Model for Multi-lineage Human Development
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Kun Zhang | P. Mali | Daniella McDonald | Yan Wu | Amir Dailamy | Justin Tat | Udit Parekh | Dongxin Zhao | Michael Hu | A. Tipps
[1] Jacob Cohen. Statistical Power Analysis for the Behavioral Sciences , 1969, The SAGE Encyclopedia of Research Design.
[2] R. Tibshirani,et al. Lasso and Elastic-Net Regularized Generalized Linear Models [R package glmnet version 4.0-2] , 2020 .
[3] A. van Oudenaarden,et al. An in vitro model of early anteroposterior organization during human development , 2020, Nature.
[4] L1 syndrome , 2020, Definitions.
[5] David van Dijk,et al. Uncovering axes of variation among single-cell cancer specimens , 2020, Nature Methods.
[6] T. Lassmann,et al. Systematic assessment of tissue dissociation and storage biases in single-cell and single-nucleus RNA-seq workflows , 2020, Genome Biology.
[7] Fenglin Liu,et al. Systematic comparative analysis of single-nucleotide variant detection methods from single-cell RNA sequencing data , 2019, Genome Biology.
[8] M. Gerstein,et al. A Single-Cell Transcriptomic Atlas of Human Neocortical Development during Mid-gestation , 2019, Neuron.
[9] Allan R. Jones,et al. Conserved cell types with divergent features in human versus mouse cortex , 2019, Nature.
[10] Paul J. Hoffman,et al. Comprehensive Integration of Single-Cell Data , 2018, Cell.
[11] Sean K. Simmons,et al. Individual brain organoids reproducibly form cell diversity of the human cerebral cortex , 2019, Nature.
[12] Samuel Demharter,et al. Joint analysis of heterogeneous single-cell RNA-seq dataset collections , 2019, Nature Methods.
[13] Samantha A. Morris,et al. CellTag Indexing: genetic barcode-based sample multiplexing for single-cell genomics , 2019, Genome Biology.
[14] Berthold Göttgens,et al. A single-cell molecular map of mouse gastrulation and early organogenesis , 2019, Nature.
[15] Simon Cockell,et al. Deconstructing Retinal Organoids: Single Cell RNA‐Seq Reveals the Cellular Components of Human Pluripotent Stem Cell‐Derived Retina , 2019, Stem cells.
[16] Andrew J. Hill,et al. The single cell transcriptional landscape of mammalian organogenesis , 2019, Nature.
[17] Melissa C Skala,et al. Reproducibility and staging of 3D human retinal organoids across multiple pluripotent stem cell lines , 2019, Development.
[18] Lai Guan Ng,et al. Dimensionality reduction for visualizing single-cell data using UMAP , 2018, Nature Biotechnology.
[19] A. Oshlack,et al. Evaluation of variability in human kidney organoids , 2018, Nature Methods.
[20] Daniel J. Miller,et al. Spatiotemporal transcriptomic divergence across human and macaque brain development , 2018, Science.
[21] Madeline A. Lancaster,et al. Exploring landscapes of brain morphogenesis with organoids , 2018, Development.
[22] Kun Zhang,et al. Mapping Cellular Reprogramming via Pooled Overexpression Screens with Paired Fitness and Single-Cell RNA-Sequencing Readout. , 2018, Cell systems.
[23] A. Schambach,et al. Human Teratoma-Derived Hematopoiesis Is a Highly Polyclonal Process Supported by Human Umbilical Vein Endothelial Cells , 2018, Stem cell reports.
[24] D. Zack,et al. Three-Dimensional Retinal Organoids Facilitate the Investigation of Retinal Ganglion Cell Development, Organization and Neurite Outgrowth from Human Pluripotent Stem Cells , 2018, Scientific Reports.
[25] Martin J. Aryee,et al. In vivo CRISPR editing with no detectable genome-wide off-target mutations , 2018, Nature.
[26] Runx1-Stat3 signaling regulates the epithelial stem cells in continuously growing incisors , 2018, Scientific Reports.
[27] M. Kyba,et al. Skeletal Muscle Stem Cells from PSC-Derived Teratomas Have Functional Regenerative Capacity. , 2018, Cell stem cell.
[28] Kevin R. Moon,et al. Recovering Gene Interactions from Single-Cell Data Using Data Diffusion , 2018, Cell.
[29] Pablo Tamayo,et al. Visualizing and interpreting single-cell gene expression datasets with Similarity Weighted Nonnegative Embedding , 2018, bioRxiv.
[30] Allon M. Klein,et al. Single-cell mapping of gene expression landscapes and lineage in the zebrafish embryo , 2018, Science.
[31] A. Regev,et al. Single-cell reconstruction of developmental trajectories during zebrafish embryogenesis , 2018, Science.
[32] P. Madeddu,et al. Concise Review: The Regenerative Journey of Pericytes Toward Clinical Translation , 2018, Stem cells.
[33] Lu Wen,et al. Tracing the temporal-spatial transcriptome landscapes of the human fetal digestive tract using single-cell RNA-sequencing , 2018, Nature Cell Biology.
[34] A. Torkamani,et al. Diverse reprogramming codes for neuronal identity , 2018, Nature.
[35] Paul Hoffman,et al. Integrating single-cell transcriptomic data across different conditions, technologies, and species , 2018, Nature Biotechnology.
[36] J. Roux,et al. Rett syndrome from bench to bedside: recent advances , 2018, F1000Research.
[37] D. Bartel. Metazoan MicroRNAs , 2018, Cell.
[38] Richard A. Muscat,et al. Single-cell profiling of the developing mouse brain and spinal cord with split-pool barcoding , 2018, Science.
[39] Jie Qiao,et al. A single-cell RNA-seq survey of the developmental landscape of the human prefrontal cortex , 2018, Nature.
[40] Nazish Sayed,et al. Modeling human diseases with induced pluripotent stem cells: from 2D to 3D and beyond , 2018, Development.
[41] Martin J. Aryee,et al. In vivo CRISPR-Cas gene editing with no detectable genome-wide off-target mutations , 2018, bioRxiv.
[42] S. Orkin,et al. Mapping the Mouse Cell Atlas by Microwell-Seq , 2018, Cell.
[43] Leland McInnes,et al. UMAP: Uniform Manifold Approximation and Projection for Dimension Reduction , 2018, ArXiv.
[44] Hyojin Kim,et al. TRRUST v2: an expanded reference database of human and mouse transcriptional regulatory interactions , 2017, Nucleic Acids Res..
[45] P. Arlotta,et al. Studying the Brain in a Dish: 3D Cell Culture Models of Human Brain Development and Disease. , 2018, Current topics in developmental biology.
[46] R. Bloomquist,et al. A quiescent cell population replenishes mesenchymal stem cells to drive accelerated growth in mouse incisors , 2018, Nature Communications.
[47] Intawat Nookaew,et al. Single-cell gene expression analysis reveals regulators of distinct cell subpopulations among developing human neurons , 2017, Genome research.
[48] L. Vallier,et al. Variability of human pluripotent stem cell lines. , 2017, Current opinion in genetics & development.
[49] Claudia C. Wehrspaun,et al. Synthetic RNA-Based Immunomodulatory Gene Circuits for Cancer Immunotherapy , 2017, Cell.
[50] A. Wilkinson,et al. In Vivo Generation of Engraftable Murine Hematopoietic Stem Cells by Gfi1b, c-Fos, and Gata2 Overexpression within Teratoma , 2017, Stem cell reports.
[51] T. Ohtsuka,et al. Hes5 regulates the transition timing of neurogenesis and gliogenesis in mammalian neocortical development , 2017, Development.
[52] Stem cells: Organoid variability examined , 2017, Nature Methods.
[53] Hirohide Saito,et al. Cell-type-specific genome editing with a microRNA-responsive CRISPR–Cas9 switch , 2017, Nucleic acids research.
[54] Daniel R. Berger,et al. Cell diversity and network dynamics in photosensitive human brain organoids , 2017, Nature.
[55] Hans Clevers,et al. Disease Modeling in Stem Cell-Derived 3D Organoid Systems. , 2017, Trends in molecular medicine.
[56] V. Menon,et al. Dynamics of embryonic stem cell differentiation inferred from single-cell transcriptomics show a series of transitions through discrete cell states , 2017, eLife.
[57] A. Martinez-Arias,et al. The hope and the hype of organoid research , 2017, Development.
[58] Richard A. Muscat,et al. Scaling single cell transcriptomics through split pool barcoding , 2017, bioRxiv.
[59] Andrew C. Adey,et al. Single-Cell Transcriptional Profiling of a Multicellular Organism , 2017 .
[60] Rebecca D Hodge,et al. A Single-Cell Roadmap of Lineage Bifurcation in Human ESC Models of Embryonic Brain Development. , 2017, Cell stem cell.
[61] L. Mureşan,et al. Early born neurons are abnormally positioned in the doublecortin knockout hippocampus , 2016, Human molecular genetics.
[62] André F. Rendeiro,et al. Pooled CRISPR screening with single-cell transcriptome read-out , 2017, Nature Methods.
[63] Lei S. Qi,et al. Repurposing CRISPR System for Transcriptional Activation. , 2017, Advances in experimental medicine and biology.
[64] J. Spence,et al. hPSC-derived lung and intestinal organoids as models of human fetal tissue. , 2016, Developmental biology.
[65] M. Kay,et al. Increased precursor microRNA-21 following status epilepticus can compete with mature microRNA-21 to alter translation , 2016, Experimental Neurology.
[66] Thomas M. Norman,et al. A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response , 2016, Cell.
[67] Thomas M. Norman,et al. Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens , 2016, Cell.
[68] Kathleen F. Kerr,et al. CNS tau efflux via exosomes is likely increased in Parkinson's disease but not in Alzheimer's disease , 2016, Alzheimer's & Dementia.
[69] Charles A. Gersbach,et al. Targeted Epigenetic Remodeling of Endogenous Loci by CRISPR/Cas9-Based Transcriptional Activators Directly Converts Fibroblasts to Neuronal Cells. , 2016, Cell stem cell.
[70] A. Tonevitsky,et al. L1CAM: Cell adhesion and more. , 2016, Progress in histochemistry and cytochemistry.
[71] Grace X. Y. Zheng,et al. Massively parallel digital transcriptional profiling of single cells , 2016, Nature Communications.
[72] Matthew C. Canver,et al. Analyzing CRISPR genome-editing experiments with CRISPResso , 2016, Nature Biotechnology.
[73] Hans Clevers,et al. Modeling Development and Disease with Organoids , 2016, Cell.
[74] Gabriela Alexe,et al. Characterizing genomic alterations in cancer by complementary functional associations , 2016, Nature Biotechnology.
[75] K. Iwata,et al. Regulation of transient receptor potential vanilloid 1 expression in trigeminal ganglion neurons via methyl-CpG binding protein 2 signaling contributes tongue heat sensitivity and inflammatory hyperalgesia in mice , 2016, Molecular pain.
[76] R. Shivdasani,et al. Stomach development, stem cells and disease , 2016, Development.
[77] Jeffrey M Karp,et al. Engineering Stem Cell Organoids. , 2016, Cell stem cell.
[78] A. Ben-Ze'ev,et al. Clusterin, a gene enriched in intestinal stem cells, is required for L1-mediated colon cancer metastasis , 2015, Oncotarget.
[79] Bon-Kyoung Koo,et al. Modeling mouse and human development using organoid cultures , 2015, Development.
[80] Y. Groner,et al. Runx1 Transcription Factor Is Required for Myoblasts Proliferation during Muscle Regeneration , 2015, PLoS genetics.
[81] N. Benvenisty,et al. TeratoScore: Assessing the Differentiation Potential of Human Pluripotent Stem Cells by Quantitative Expression Analysis of Teratomas , 2015, Stem cell reports.
[82] Shinya Yamanaka,et al. Efficient Detection and Purification of Cell Populations Using Synthetic MicroRNA Switches. , 2015, Cell stem cell.
[83] Allon M. Klein,et al. Droplet Barcoding for Single-Cell Transcriptomics Applied to Embryonic Stem Cells , 2015, Cell.
[84] D. Su,et al. An updated role of microRNA-124 in central nervous system disorders: a review , 2015, Front. Cell. Neurosci..
[85] Hayley E. Francies,et al. Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients , 2015, Cell.
[86] Evan Z. Macosko,et al. Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets , 2015, Cell.
[87] Richard L. Mort,et al. The melanocyte lineage in development and disease , 2015, Development.
[88] M. Spector,et al. Organoid Models of Human and Mouse Ductal Pancreatic Cancer , 2015, Cell.
[89] Hans Clevers,et al. In vitro expansion of human gastric epithelial stem cells and their responses to bacterial infection. , 2015, Gastroenterology.
[90] A. van Oudenaarden,et al. Transformation of intestinal stem cells into gastric stem cells on loss of transcription factor Cdx2 , 2014, Nature Communications.
[91] W. Huber,et al. Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2 , 2014, Genome Biology.
[92] Hans Clevers,et al. Organoid Cultures Derived from Patients with Advanced Prostate Cancer , 2014, Cell.
[93] Neville E. Sanjana,et al. Improved vectors and genome-wide libraries for CRISPR screening , 2014, Nature Methods.
[94] M. Hill,et al. The emerging roles of TCF4 in disease and development. , 2014, Trends in molecular medicine.
[95] Allan R. Jones,et al. Transcriptional Landscape of the Prenatal Human Brain , 2014, Nature.
[96] L. Pozzo-Miller,et al. BDNF deregulation in Rett syndrome , 2014, Neuropharmacology.
[97] A. Fischer,et al. TTC7A mutations disrupt intestinal epithelial apicobasal polarity. , 2014, The Journal of clinical investigation.
[98] Charity W. Law,et al. voom: precision weights unlock linear model analysis tools for RNA-seq read counts , 2014, Genome Biology.
[99] A. Percy,et al. Evaluation of current pharmacological treatment options in the management of Rett syndrome: from the present to future therapeutic alternatives. , 2013, Current clinical pharmacology.
[100] L. Studer,et al. Build-a-brain. , 2013, Cell stem cell.
[101] M. Forrest,et al. Knockdown of Human TCF4 Affects Multiple Signaling Pathways Involved in Cell Survival, Epithelial to Mesenchymal Transition and Neuronal Differentiation , 2013, PLoS ONE.
[102] H. Nakauchi,et al. Generation of engraftable hematopoietic stem cells from induced pluripotent stem cells by way of teratoma formation. , 2013, Molecular therapy : the journal of the American Society of Gene Therapy.
[103] Hans Clevers,et al. A functional CFTR assay using primary cystic fibrosis intestinal organoids , 2013, Nature Medicine.
[104] Richard S. Zemel,et al. Stochastic k-Neighborhood Selection for Supervised and Unsupervised Learning , 2013, ICML.
[105] T. Tumbar,et al. New insights into the role of Runx1 in epithelial stem cell biology and pathology , 2013, Journal of cellular biochemistry.
[106] Luke A. Gilbert,et al. Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression , 2013, Cell.
[107] D. Neuberg,et al. In vivo generation of transplantable human hematopoietic cells from induced pluripotent stem cells. , 2013, Blood.
[108] S. Friedman,et al. Vascular Injury Triggers Krüppel-Like Factor 6 Mobilization and Cooperation With Specificity Protein 1 to Promote Endothelial Activation Through Upregulation of the Activin Receptor-Like Kinase 1 Gene , 2013, Circulation research.
[109] Thomas R. Gingeras,et al. STAR: ultrafast universal RNA-seq aligner , 2013, Bioinform..
[110] G. Meijer,et al. Runx1 is a tumor suppressor gene in the mouse gastrointestinal tract , 2012, Cancer science.
[111] Tao He,et al. Normal and disease-related biological functions of Twist1 and underlying molecular mechanisms , 2011, Cell Research.
[112] J. Ignatius,et al. Pitt-Hopkins Syndrome , 2011, Molecular Syndromology.
[113] Hans Clevers,et al. Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium. , 2011, Gastroenterology.
[114] Hans Clevers,et al. Isolation and in vitro expansion of human colonic stem cells , 2011, Nature Medicine.
[115] Isabelle S. Peter,et al. Transphyletic conservation of developmental regulatory state in animal evolution , 2011, Proceedings of the National Academy of Sciences.
[116] F. Guillemot,et al. A novel function of the proneural factor Ascl1 in progenitor proliferation identified by genome-wide characterization of its targets. , 2011, Genes & development.
[117] Eric H. Davidson,et al. Evolution of Gene Regulatory Networks Controlling Body Plan Development , 2011, Cell.
[118] C. Schaniel,et al. Generation of anterior foregut endoderm from human embryonic and induced pluripotent stem cells , 2011, Nature Biotechnology.
[119] L. Peshkin,et al. Remodeling of the Metabolome during Early Frog Development , 2011, PloS one.
[120] H. Abdi,et al. Principal component analysis , 2010 .
[121] Hans-Peter Kriegel,et al. Can Shared-Neighbor Distances Defeat the Curse of Dimensionality? , 2010, SSDBM.
[122] Liang-Hu Qu,et al. MicroRNA-21 promotes cell proliferation and down-regulates the expression of programmed cell death 4 (PDCD4) in HeLa cervical carcinoma cells. , 2009, Biochemical and biophysical research communications.
[123] Hongwei Zhang,et al. Characterization of SoxB2 and SoxC genes in amphioxus (Branchiostoma belcheri): Implications for their evolutionary conservation , 2009, Science in China Series C: Life Sciences.
[124] K. Nave,et al. Neurod1 is essential for the survival and maturation of adult-born neurons , 2009, Nature Neuroscience.
[125] G. Stein,et al. Pluripotency: Toward a gold standard for human ES and iPS cells , 2009, Journal of cellular physiology.
[126] Yandan Yao,et al. MiR-21 Indicates Poor Prognosis in Tongue Squamous Cell Carcinomas as an Apoptosis Inhibitor , 2009, Clinical Cancer Research.
[127] Raghu Kalluri,et al. The basics of epithelial-mesenchymal transition. , 2009, The Journal of clinical investigation.
[128] H. Clevers,et al. Single Lgr5 stem cells build cryptvillus structures in vitro without a mesenchymal niche , 2009, Nature.
[129] K. Kaestner,et al. Establishment of intestinal identity and epithelial-mesenchymal signaling by Cdx2. , 2009, Developmental cell.
[130] Michael S. Becker,et al. Fate tracing reveals the endothelial origin of hematopoietic stem cells. , 2008, Cell stem cell.
[131] John McAnally,et al. The endothelial-specific microRNA miR-126 governs vascular integrity and angiogenesis. , 2008, Developmental cell.
[132] Frank J. Slack,et al. MicroRNAs and cancer: An overview , 2008, Cell cycle.
[133] N. Colburn,et al. MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene , 2008, Oncogene.
[134] Shuomin Zhu,et al. MicroRNA-21 targets tumor suppressor genes in invasion and metastasis , 2008, Cell Research.
[135] L. Zon,et al. Teratoma formation assays with human embryonic stem cells: a rationale for one type of human-animal chimera. , 2007, Cell stem cell.
[136] B. Hogan,et al. Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm , 2007, Development.
[137] R. Shivdasani. MicroRNAs: regulators of gene expression and cell differentiation. , 2006, Blood.
[138] M. Wegner,et al. The Runx1/AML1 transcription factor selectively regulates development and survival of TrkA nociceptive sensory neurons , 2006, Nature Neuroscience.
[139] H. Horvitz,et al. MicroRNA expression profiles classify human cancers , 2005, Nature.
[140] Lena Smirnova,et al. Regulation of miRNA expression during neural cell specification , 2005, The European journal of neuroscience.
[141] V. Ambros. The functions of animal microRNAs , 2004, Nature.
[142] S. Ramaswamy,et al. Twist, a Master Regulator of Morphogenesis, Plays an Essential Role in Tumor Metastasis , 2004, Cell.
[143] R. Beddington,et al. Hex homeobox gene-dependent tissue positioning is required for organogenesis of the ventral pancreas , 2004, Development.
[144] D. Bartel. MicroRNAs Genomics, Biogenesis, Mechanism, and Function , 2004, Cell.
[145] T. Tuschl,et al. Identification of Tissue-Specific MicroRNAs from Mouse , 2002, Current Biology.
[146] David Thissen,et al. Quick and Easy Implementation of the Benjamini-Hochberg Procedure for Controlling the False Positive Rate in Multiple Comparisons , 2002 .
[147] K. Kaestner,et al. Cdx2 ectopic expression induces gastric intestinal metaplasia in transgenic mice. , 2002, Gastroenterology.
[148] W. Böcker. [WHO classification of breast tumors and tumors of the female genital organs: pathology and genetics]. , 2002, Verhandlungen der Deutschen Gesellschaft fur Pathologie.
[149] C. Goding,et al. Mitf from neural crest to melanoma: signal transduction and transcription in the melanocyte lineage. , 2000, Genes & development.
[150] J. Beckmann,et al. Human-mouse differences in the embryonic expression patterns of developmental control genes and disease genes. , 2000, Human molecular genetics.
[151] H. Sebastian Seung,et al. Learning the parts of objects by non-negative matrix factorization , 1999, Nature.
[152] James Hanken,et al. There is no highly conserved embryonic stage in the vertebrates: implications for current theories of evolution and development , 1997, Anatomy and Embryology.
[153] Simon Conway Morris,et al. The shape of life, genes, development, and the evolution of animal form , 1996 .
[154] R. Raff. Understanding Evolution: The Next Step. (Book Reviews: The Shape of Life. Genes, Development, and the Evolution of Animal Form.) , 1996 .
[155] I. Jolliffe. Principal Component Analysis , 2005 .
[156] G. B. Pierce,et al. Teratomas: definitions and terminology. , 1975 .
[157] John W. Sammon,et al. A Nonlinear Mapping for Data Structure Analysis , 1969, IEEE Transactions on Computers.
[158] M. Misrabi. The ependymal cells. , 1969, Journal of Anatomy.
[159] L. C. Stevens. The biology of teratomas. , 1967, Advances in morphogenesis.
[160] L. C. Stevens. The biology of teratomas including evidence indicating their origin form primordial germ cells. , 1962, L' Annee biologique.
[161] W. Thurlbeck,et al. Solid teratoma of the ovary. A clinicopathological analysis of 9 cases , 1960, Cancer.
[162] J. F. Campbell. Solid teratoma of the ovary. , 1947, Canadian Medical Association journal.
[163] F. Wilcoxon,et al. Individual comparisons of grouped data by ranking methods. , 1946, Journal of economic entomology.
[164] R. A. Willis. The histogenesis of neural tissue in teratomas , 1936 .
[165] R. A. Willis. The structure of teratomata , 1935 .