Advancing osteochondral tissue engineering: bone morphogenetic protein, transforming growth factor, and fibroblast growth factor signaling drive ordered differentiation of periosteal cells resulting in stable cartilage and bone formation in vivo

[1]  Jonathan C. Bernhard,et al.  Recapitulation of physiological spatiotemporal signals promotes in vitro formation of phenotypically stable human articular cartilage , 2017, Proceedings of the National Academy of Sciences.

[2]  Jerry C. Hu,et al.  Cell-based tissue engineering strategies used in the clinical repair of articular cartilage. , 2016, Biomaterials.

[3]  D. Hart,et al.  Synovial mesenchymal stem cells from osteo- or rheumatoid arthritis joints exhibit good potential for cartilage repair using a scaffold-free tissue engineering approach. , 2016, Osteoarthritis and cartilage.

[4]  N. Kops,et al.  Silencing of Antichondrogenic MicroRNA‐221 in Human Mesenchymal Stem Cells Promotes Cartilage Repair In Vivo , 2016, Stem cells.

[5]  Nehal A. Shah,et al.  High Failure Rate of a Decellularized Osteochondral Allograft for the Treatment of Cartilage Lesions , 2016, The American journal of sports medicine.

[6]  K. Mak,et al.  Type V Collagen in Health, Disease, and Fibrosis , 2016, Anatomical record.

[7]  I. Martin,et al.  Cartilage Repair in the Inflamed Joint: Considerations for Biological Augmentation Toward Tissue Regeneration. , 2016, Tissue engineering. Part B, Reviews.

[8]  F. Luyten,et al.  Combinatorial Analysis of Growth Factors Reveals the Contribution of Bone Morphogenetic Proteins to Chondrogenic Differentiation of Human Periosteal Cells. , 2016, Tissue engineering. Part C, Methods.

[9]  A. Reddi,et al.  Stimulation of Superficial Zone Protein/Lubricin/PRG4 by Transforming Growth Factor-β in Superficial Zone Articular Chondrocytes and Modulation by Glycosaminoglycans. , 2015, Tissue engineering. Part A.

[10]  A. Lassar,et al.  Identification of a Prg4‐Expressing Articular Cartilage Progenitor Cell Population in Mice , 2015, Arthritis & rheumatology.

[11]  Jerry C. Hu,et al.  TGF‐β1, GDF‐5, and BMP‐2 Stimulation Induces Chondrogenesis in Expanded Human Articular Chondrocytes and Marrow‐Derived Stromal Cells , 2015, Stem cells.

[12]  P. Brama,et al.  Long-Term Expansion, Enhanced Chondrogenic Potential, and Suppression of Endochondral Ossification of Adult Human MSCs via WNT Signaling Modulation , 2015, Stem cell reports.

[13]  J. Adams,et al.  Lysophosphatidic acid mediates fibrosis in injured joints by regulating collagen type I biosynthesis. , 2015, Osteoarthritis and cartilage.

[14]  Di Chen,et al.  TGF-β signaling and the development of osteoarthritis , 2014, Bone Research.

[15]  W. Bugbee,et al.  Fresh osteochondral allograft transplantation for the knee: current concepts. , 2014, The Journal of the American Academy of Orthopaedic Surgeons.

[16]  W. Richter,et al.  No effect of subperiosteal growth factor application on periosteal neo-chondrogenesis in osteoperiosteal bone grafts for osteochondral defect repair , 2013, International Orthopaedics.

[17]  N. Südkamp,et al.  Reoperative characteristics after microfracture of knee cartilage lesions in 454 patients , 2013, Knee Surgery, Sports Traumatology, Arthroscopy.

[18]  Christopher S. Chen,et al.  Adhesive and mechanical regulation of mesenchymal stem cell differentiation in human bone marrow and periosteum-derived progenitor cells , 2012, Biology Open.

[19]  R. Bank,et al.  Osteoarthritis-related fibrosis is associated with both elevated pyridinoline cross-link formation and lysyl hydroxylase 2b expression. , 2012, Osteoarthritis and cartilage.

[20]  F. Mallein-Gerin,et al.  Chondrocytes or adult stem cells for cartilage repair: the indisputable role of growth factors. , 2012, Injury.

[21]  Liesbet Geris,et al.  The combined bone forming capacity of human periosteal derived cells and calcium phosphates. , 2011, Biomaterials.

[22]  F. O'Brien,et al.  In-vivo generation of bone via endochondral ossification by in-vitro chondrogenic priming of adult human and rat mesenchymal stem cells , 2011, BMC musculoskeletal disorders.

[23]  W. B. van den Berg,et al.  Smad signaling determines chondrogenic differentiation of bone-marrow-derived mesenchymal stem cells: inhibition of Smad1/5/8P prevents terminal differentiation and calcification. , 2011, Tissue engineering. Part A.

[24]  Ivan Martin,et al.  Recapitulation of endochondral bone formation using human adult mesenchymal stem cells as a paradigm for developmental engineering , 2010, Proceedings of the National Academy of Sciences.

[25]  P. Lenz,et al.  Presence of subchondral bone marrow edema at the time of treatment represents a negative prognostic factor for early outcome after autologous chondrocyte implantation , 2010, Archives of Orthopaedic and Trauma Surgery.

[26]  J. Kim,et al.  Effect of serum and growth factors on chondrogenic differentiation of synovium-derived stromal cells. , 2009, Tissue engineering. Part A.

[27]  Jennifer H Elisseeff,et al.  Characterization of Human Mesenchymal Stem Cell-Engineered Cartilage: Analysis of Its Ultrastructure, Cell Density and Chondrocyte Phenotype Compared to Native Adult and Fetal Cartilage , 2009, Cells Tissues Organs.

[28]  J. Schrooten,et al.  A clinically relevant model of osteoinduction: a process requiring calcium phosphate and BMP/Wnt signalling , 2009, Journal of cellular and molecular medicine.

[29]  J. Urban,et al.  Nutrient gradients in engineered cartilage: Metabolic kinetics measurement and mass transfer modeling , 2008, Biotechnology and bioengineering.

[30]  Hiromichi Fujie,et al.  Cartilage repair using an in vitro generated scaffold-free tissue-engineered construct derived from porcine synovial mesenchymal stem cells. , 2007, Biomaterials.

[31]  T. Trzaska,et al.  Articular cartilage defects: study of 25,124 knee arthroscopies. , 2007, The Knee.

[32]  H. Fujioka,et al.  Treatment of a full-thickness articular cartilage defect in the femoral condyle of an athlete with autologous bone-marrow stromal cells. , 2007, Osteoarthritis and cartilage.

[33]  Thomas D Brown,et al.  Posttraumatic Osteoarthritis: A First Estimate of Incidence, Prevalence, and Burden of Disease , 2006, Journal of orthopaedic trauma.

[34]  R. Tuan,et al.  Chondrogenic differentiation and functional maturation of bovine mesenchymal stem cells in long-term agarose culture. , 2006, Osteoarthritis and cartilage.

[35]  Anja Winter,et al.  Induction of Intervertebral Disc–Like Cells From Adult Mesenchymal Stem Cells , 2005, Stem cells.

[36]  Shigeyuki Wakitani,et al.  Autologous Bone Marrow Stromal Cell Transplantation for Repair of Full-Thickness Articular Cartilage Defects in Human Patellae: Two Case Reports , 2004, Cell transplantation.

[37]  J. Tramper,et al.  Oxygen gradients in tissue‐engineered Pegt/Pbt cartilaginous constructs: Measurement and modeling , 2004, Biotechnology and bioengineering.

[38]  B. Swoboda,et al.  Tenascin and aggrecan expression by articular chondrocytes is influenced by interleukin 1β: a possible explanation for the changes in matrix synthesis during osteoarthritis , 2004, Annals of the rheumatic diseases.

[39]  Beat Hammer,et al.  In vivo efficacy of bone-marrow-coated polycaprolactone scaffolds for the reconstruction of orbital defects in the pig. , 2003, Journal of biomedical materials research. Part B, Applied biomaterials.

[40]  S W O'Driscoll,et al.  The role of periosteum in cartilage repair. , 2001, Clinical orthopaedics and related research.

[41]  M. Hochberg,et al.  Joint Injury in Young Adults and Risk for Subsequent Knee and Hip Osteoarthritis , 2000, Annals of Internal Medicine.

[42]  D Coggon,et al.  Individual risk factors for hip osteoarthritis: obesity, hip injury, and physical activity. , 1998, American journal of epidemiology.

[43]  B. P. Smith,et al.  Cartilage injuries: a review of 31,516 knee arthroscopies. , 1997, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[44]  C. Ohlsson,et al.  Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation. , 1994, The New England journal of medicine.

[45]  J. Lian,et al.  Induction of bone‐related proteins, osteocalcin and osteopontin, and their matrix ultrastructural localization with development of chondrocyte hypertrophy in vitro , 1993, Journal of cellular biochemistry.

[46]  W W Hauck,et al.  The association of knee injury and obesity with unilateral and bilateral osteoarthritis of the knee. , 1989, American journal of epidemiology.

[47]  Hajime Ohgushi,et al.  Repair of articular cartilage defects in the patello‐femoral joint with autologous bone marrow mesenchymal cell transplantation: three case reports involving nine defects in five knees , 2007, Journal of tissue engineering and regenerative medicine.

[48]  H. Kuokkanen,et al.  Autogenous osteoperiosteal grafts in the reconstruction of full-thickness joint surface defects , 2004, International Orthopaedics.

[49]  F. Luyten,et al.  Human periosteum-derived cells maintain phenotypic stability and chondrogenic potential throughout expansion regardless of donor age. , 2001, Arthritis and rheumatism.

[50]  W. B. van den Berg,et al.  Osteoarthritis-like changes in the murine knee joint resulting from intra-articular transforming growth factor-beta injections. , 2000, Osteoarthritis and cartilage.

[51]  G. Vunjak‐Novakovic,et al.  Mass transfer studies of tissue engineered cartilage. , 1996, Tissue engineering.