The transcriptional response to oxidative stress is part of, but not sufficient for, insulin resistance in adipocytes

[1]  K. Raghu,et al.  Development of insulin resistance through sprouting of inflammatory markers during hypoxia in 3T3‐L1 adipocytes and amelioration with curcumin , 2017, European journal of pharmacology.

[2]  Sean J. Humphrey,et al.  The amino acid transporter, SLC1A3, is plasma membrane‐localised in adipocytes and its activity is insensitive to insulin , 2017, FEBS letters.

[3]  Zdenka Kuncic,et al.  ORTI: An Open-Access Repository of Transcriptional Interactions for Interrogating Mammalian Gene Expression Data , 2016, PloS one.

[4]  Elias S. J. Arnér,et al.  Thioredoxin reductase 1 suppresses adipocyte differentiation and insulin responsiveness , 2016, Scientific Reports.

[5]  Hiroyuki Kubota,et al.  Trans-Omics: How To Reconstruct Biochemical Networks Across Multiple 'Omic' Layers. , 2016, Trends in biotechnology.

[6]  R. Milo,et al.  SnapShot: Timescales in Cell Biology , 2016, Cell.

[7]  Minoru Kanehisa,et al.  KEGG as a reference resource for gene and protein annotation , 2015, Nucleic Acids Res..

[8]  J. Yun,et al.  Curcumin induces brown fat-like phenotype in 3T3-L1 and primary white adipocytes. , 2016, The Journal of nutritional biochemistry.

[9]  B. Fischer Lessons Learned. , 2016, Schizophrenia bulletin.

[10]  S. Merali,et al.  Excessive caloric intake acutely causes oxidative stress, GLUT4 carbonylation, and insulin resistance in healthy men , 2015, Science Translational Medicine.

[11]  Jean Yee Hwa Yang,et al.  Knowledge-Based Analysis for Detecting Key Signaling Events from Time-Series Phosphoproteomics Data , 2015, PLoS Comput. Biol..

[12]  Wenyi Lu,et al.  Mitochondrial Reactive Oxygen Species Regulate Adipocyte Differentiation of Mesenchymal Stem Cells in Hematopoietic Stress Induced by Arabinosylcytosine , 2015, PloS one.

[13]  S. Paglialunga,et al.  In adipose tissue, increased mitochondrial emission of reactive oxygen species is important for short-term high-fat diet-induced insulin resistance in mice , 2015, Diabetologia.

[14]  Ram Rup Sarkar,et al.  Comparison of human cell signaling pathway databases—evolution, drawbacks and challenges , 2015, Database J. Biol. Databases Curation.

[15]  Matthew E. Ritchie,et al.  limma powers differential expression analyses for RNA-sequencing and microarray studies , 2015, Nucleic acids research.

[16]  Fionn Murtagh,et al.  Ward’s Hierarchical Agglomerative Clustering Method: Which Algorithms Implement Ward’s Criterion? , 2011, Journal of Classification.

[17]  D. James,et al.  ISL1 Regulates Peroxisome Proliferator-Activated Receptor γ Activation and Early Adipogenesis via Bone Morphogenetic Protein 4-Dependent and -Independent Mechanisms , 2014, Molecular and Cellular Biology.

[18]  Jian Peng,et al.  Mature miR-183, negatively regulated by transcription factor GATA3, promotes 3T3-L1 adipogenesis through inhibition of the canonical Wnt/β-catenin signaling pathway by targeting LRP6. , 2014, Cellular signalling.

[19]  D. James,et al.  The Role of the Niemann-Pick Disease, Type C1 Protein in Adipocyte Insulin Action , 2014, PloS one.

[20]  P. Neufer,et al.  Mitochondrial Respiratory Capacity and Content Are Normal in Young Insulin-Resistant Obese Humans , 2013, Diabetes.

[21]  K. Fisher-Wellman,et al.  Mitochondrial glutathione depletion reveals a novel role for the pyruvate dehydrogenase complex as a key H2O2-emitting source under conditions of nutrient overload. , 2013, Free radical biology & medicine.

[22]  Ernest Fraenkel,et al.  Analysis of in vitro insulin-resistance models and their physiological relevance to in vivo diet-induced adipose insulin resistance. , 2013, Cell reports.

[23]  Christine Nardini,et al.  Signalling pathway database usability: lessons learned. , 2013, Molecular bioSystems.

[24]  Dean P. Jones,et al.  Selective Targeting of the Cysteine Proteome by Thioredoxin and Glutathione Redox Systems , 2013, Molecular & Cellular Proteomics.

[25]  R. Stocker,et al.  Neutrophil‐mediated oxidation of erythrocyte peroxiredoxin 2 as a potential marker of oxidative stress in inflammation , 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[26]  A. Contreras-Ferrat,et al.  Insulin-Dependent H2O2 Production Is Higher in Muscle Fibers of Mice Fed with a High-Fat Diet , 2013, International journal of molecular sciences.

[27]  I. Simon,et al.  Studying and modelling dynamic biological processes using time-series gene expression data , 2012, Nature Reviews Genetics.

[28]  K. Huh,et al.  Peroxiredoxin 3 is a key molecule regulating adipocyte oxidative stress, mitochondrial biogenesis, and adipokine expression. , 2012, Antioxidants & redox signaling.

[29]  P. Legendre,et al.  Ward's Hierarchical Clustering Method: Clustering Criterion and Agglomerative Algorithm , 2011, ArXiv.

[30]  Saeed Tavazoie,et al.  Analysis of gene networks in white adipose tissue development reveals a role for ETS2 in adipogenesis , 2011, Development.

[31]  Helga Thorvaldsdóttir,et al.  Molecular signatures database (MSigDB) 3.0 , 2011, Bioinform..

[32]  J. Krycer,et al.  Cross-talk between the Androgen Receptor and the Liver X Receptor , 2011, The Journal of Biological Chemistry.

[33]  Edward T Chouchani,et al.  Proteomic approaches to the characterization of protein thiol modification , 2011, Current opinion in chemical biology.

[34]  Rafael A. Irizarry,et al.  A framework for oligonucleotide microarray preprocessing , 2010, Bioinform..

[35]  Jun-Ping Liu,et al.  Ets2 transcription factor, telomerase activity and breast cancer , 2010, Clinical and experimental pharmacology & physiology.

[36]  D. James,et al.  Insulin resistance is a cellular antioxidant defense mechanism , 2009, Proceedings of the National Academy of Sciences.

[37]  R. Ferrante,et al.  Activation of Ets‐2 by oxidative stress induces Bcl‐xL expression and accounts for glial survival in amyotrophic lateral sclerosis , 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[38]  M. Matsuda,et al.  Dysregulated glutathione metabolism links to impaired insulin action in adipocytes. , 2009, American journal of physiology. Endocrinology and metabolism.

[39]  Dayong Wu,et al.  Curcumin inhibits adipogenesis in 3T3-L1 adipocytes and angiogenesis and obesity in C57/BL mice. , 2009, The Journal of nutrition.

[40]  Hyeonjin Choi,et al.  Reactive Oxygen Species Facilitate Adipocyte Differentiation by Accelerating Mitotic Clonal Expansion* , 2009, Journal of Biological Chemistry.

[41]  Y. Li,et al.  Curcumin, a potential inhibitor of up-regulation of TNF-alpha and IL-6 induced by palmitate in 3T3-L1 adipocytes through NF-kappaB and JNK pathway. , 2009, Biomedical and environmental sciences : BES.

[42]  David E James,et al.  IRS1-independent defects define major nodes of insulin resistance. , 2008, Cell metabolism.

[43]  Caroline L. Speck,et al.  Runx1-mediated hematopoietic stem-cell emergence is controlled by a Gata/Ets/SCL-regulated enhancer. , 2007, Blood.

[44]  H. Masutani,et al.  Thioredoxin and thioredoxin-binding protein-2 in cancer and metabolic syndrome. , 2007, Free radical biology & medicine.

[45]  O. MacDougald,et al.  Adipocyte differentiation from the inside out , 2006, Nature Reviews Molecular Cell Biology.

[46]  G. Gilkeson,et al.  ETS transcription factors and regulation of immunity , 2006, Archivum Immunologiae et Therapiae Experimentalis.

[47]  E. Lander,et al.  Reactive oxygen species have a causal role in multiple forms of insulin resistance , 2006, Nature.

[48]  Pablo Tamayo,et al.  Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[49]  Q. Tong,et al.  Interaction between GATA and the C/EBP Family of Transcription Factors Is Critical in GATA-Mediated Suppression of Adipocyte Differentiation , 2005, Molecular and Cellular Biology.

[50]  Morihiro Matsuda,et al.  Increased oxidative stress in obesity and its impact on metabolic syndrome. , 2004, The Journal of clinical investigation.

[51]  Tien Hsu,et al.  Ets proteins in biological control and cancer , 2004, Journal of cellular biochemistry.

[52]  Hajime Nakamura,et al.  Glutaredoxin Exerts an Antiapoptotic Effect by Regulating the Redox State of Akt* , 2003, Journal of Biological Chemistry.

[53]  S. Reddy,et al.  Multiple cis-Elements Mediate the Transcriptional Activation of Human fra-1 by 12-O-Tetradecanoylphorbol-13-acetate in Bronchial Epithelial Cells* , 2003, Journal of Biological Chemistry.

[54]  T. Speed,et al.  Summaries of Affymetrix GeneChip probe level data. , 2003, Nucleic acids research.

[55]  Ben Bolstad,et al.  Low-level Analysis of High-density Oligonucleotide Array Data: Background, Normalization and Summarization , 2003 .

[56]  Michael C. Ostrowski,et al.  PTEN blocks insulin-mediated ETS-2 phosphorylation through MAP kinase, independently of the phosphoinositide 3-kinase pathway. , 2002, Human molecular genetics.

[57]  I. Kola,et al.  Ets-2 is induced by oxidative stress and sensitizes cells to H(2)O(2)-induced apoptosis: implications for Down's syndrome. , 2001, Biochemical and biophysical research communications.

[58]  Q. Tong,et al.  Function of GATA transcription factors in preadipocyte-adipocyte transition. , 2000, Science.

[59]  P. Goodfellow,et al.  DNA microarrays in drug discovery and development , 1999, Nature Genetics.

[60]  M. Bittner,et al.  Data management and analysis for gene expression arrays , 1998, Nature Genetics.

[61]  Y. Bernstein,et al.  Expression of the human acute myeloid leukemia gene AML1 is regulated by two promoter regions. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[62]  K. K. Jacob,et al.  A Consensus Insulin Response Element Is Activated by an ETS-related Transcription Factor (*) , 1995, The Journal of Biological Chemistry.

[63]  Y. Benjamini,et al.  Controlling the false discovery rate: a practical and powerful approach to multiple testing , 1995 .

[64]  I. Fridovich,et al.  Stable Mn(III) porphyrins mimic superoxide dismutase in vitro and substitute for it in vivo. , 1994, The Journal of biological chemistry.

[65]  J. Mitchell,et al.  Biliary excretion of glutathione and glutathione disulfide in the rat. Regulation and response to oxidative stress. , 1984, The Journal of clinical investigation.

[66]  F. Yates Contingency Tables Involving Small Numbers and the χ2 Test , 1934 .

[67]  A. I.,et al.  Neural Field Continuum Limits and the Structure–Function Partitioning of Cognitive–Emotional Brain Networks , 2023, Biology.