An ultrasensitive electrochemical immunosensor for apolipoprotein E4 based on fractal nanostructures and enzyme amplification.

[1]  Arben Merkoçi,et al.  Alzheimer's disease biomarkers detection in human samples by efficient capturing through porous magnetic microspheres and labelling with electrocatalytic gold nanoparticles. , 2015, Biosensors & bioelectronics.

[2]  Xueji Zhang,et al.  Chemical etching of bovine serum albumin-protected Au25 nanoclusters for label-free and separation-free detection of cysteamine. , 2015, Biosensors & bioelectronics.

[3]  Liqiang Liu,et al.  Dual amplified electrochemical immunosensor for highly sensitive detection of Pantoea stewartii sbusp. stewartii. , 2014, ACS applied materials & interfaces.

[4]  Q. Wei,et al.  Ultrasensitive sandwich-type electrochemical immunosensor based on a novel signal amplification strategy using highly loaded toluidine blue/gold nanoparticles decorated KIT-6/carboxymethyl chitosan/ionic liquids as signal labels. , 2014, Biosensors & bioelectronics.

[5]  Hanna Radecka,et al.  Electrochemical immunosensor for detection of antibodies against influenza A virus H5N1 in hen serum. , 2014, Biosensors & bioelectronics.

[6]  M. Medina‐Sánchez,et al.  On-chip magneto-immunoassay for Alzheimer's biomarker electrochemical detection by using quantum dots as labels. , 2014, Biosensors & bioelectronics.

[7]  K. Banerjee,et al.  MoS₂ field-effect transistor for next-generation label-free biosensors. , 2014, ACS nano.

[8]  Dongil Lee,et al.  Ionic liquid of a gold nanocluster: a versatile matrix for electrochemical biosensors. , 2014, ACS nano.

[9]  Mary F. Lopez,et al.  Assessment of peptide chemical modifications on the development of an accurate and precise multiplex selected reaction monitoring assay for apolipoprotein e isoforms. , 2014, Journal of proteome research.

[10]  Adarsh D. Radadia,et al.  Nanostructuring of Biosensing Electrodes with Nanodiamonds for Antibody Immobilization , 2014, ACS nano.

[11]  Seon Joo Park,et al.  High-performance flexible graphene aptasensor for mercury detection in mussels. , 2013, ACS nano.

[12]  Shengyuan Deng,et al.  Bioinspired polydopamine as the scaffold for the active AuNPs anchoring and the chemical simultaneously reduced graphene oxide: characterization and the enhanced biosensing application. , 2013, Biosensors & bioelectronics.

[13]  Ya-Ting Chung,et al.  An ultrasensitive nanowire-transistor biosensor for detecting dopamine release from living PC12 cells under hypoxic stimulation. , 2013, Journal of the American Chemical Society.

[14]  A. Star,et al.  Carbon nanotubes for the label-free detection of biomarkers. , 2013, ACS nano.

[15]  I. Turko,et al.  15N-labeled full-length apolipoprotein E4 as an internal standard for mass spectrometry quantification of apolipoprotein E isoforms. , 2012, Analytical chemistry.

[16]  Maurizio Prato,et al.  Highly sensitive electrochemiluminescent nanobiosensor for the detection of palytoxin. , 2012, ACS nano.

[17]  Arben Merkoçi,et al.  Signal enhancement in antibody microarrays using quantum dots nanocrystals: application to potential Alzheimer's disease biomarker screening. , 2012, Analytical chemistry.

[18]  Haifeng Dong,et al.  Fractal gold modified electrode for ultrasensitive thrombin detection. , 2012, Nanoscale.

[19]  Alexandra Bell,et al.  Turning point: Mark Lawrence , 2012, Nature.

[20]  Berislav V. Zlokovic,et al.  Apolipoprotein E controls cerebrovascular integrity via cyclophilin A , 2012, Nature.

[21]  Hongcai Gao,et al.  Coating graphene paper with 2D-assembly of electrocatalytic nanoparticles: a modular approach toward high-performance flexible electrodes. , 2012, ACS nano.

[22]  K. Bales,et al.  Reduced levels of human apoE4 protein in an animal model of cognitive impairment , 2011, Neurobiology of Aging.

[23]  G. Bu,et al.  Apolipoprotein E Regulates the Integrity of Tight Junctions in an Isoform-dependent Manner in an in Vitro Blood-Brain Barrier Model* , 2011, The Journal of Biological Chemistry.

[24]  D. Holtzman,et al.  Apolipoprotein E in Alzheimer's disease and other neurological disorders , 2011, The Lancet Neurology.

[25]  Longhua Tang,et al.  Self‐Assembled Graphene–Enzyme Hierarchical Nanostructures for Electrochemical Biosensing , 2010 .

[26]  H. Ju,et al.  Quantum‐Dot‐Functionalized Poly(styrene‐co‐acrylic acid) Microbeads: Step‐Wise Self‐Assembly, Characterization, and Applications for Sub‐femtomolar Electrochemical Detection of DNA Hybridization , 2010 .

[27]  Shana O Kelley,et al.  Programming the detection limits of biosensors through controlled nanostructuring. , 2009, Nature nanotechnology.

[28]  D. Holtzman,et al.  The Role of Apolipoprotein E in Alzheimer's Disease , 2009, Neuron.

[29]  D. Nagaraju,et al.  Electrochemically Grown Mesoporous Gold Film as High Surface Area Material for Electro-Oxidation of Alcohol in Alkaline Medium , 2009 .

[30]  C. Orvig,et al.  Medicinal inorganic chemistry approaches to passivation and removal of aberrant metal ions in disease. , 2009, Chemical reviews.

[31]  Guojun Bu,et al.  Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy , 2009, Nature Reviews Neuroscience.

[32]  H. Jacobsen,et al.  Alzheimer's disease: from pathology to therapeutic approaches. , 2009, Angewandte Chemie.

[33]  R. Tanzi,et al.  Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses , 2008, Nature Reviews Neuroscience.

[34]  Robert S. Marks,et al.  Amperometric Immunosensor for the Detection of Anti-West Nile Virus IgG , 2007 .

[35]  Joseph D. Gong,et al.  Carbon nanotube amplification strategies for highly sensitive immunodetection of cancer biomarkers. , 2006, Journal of the American Chemical Society.

[36]  H. Kozłowski,et al.  Copper homeostasis and neurodegenerative disorders (Alzheimer's, prion, and Parkinson's diseases and amyotrophic lateral sclerosis). , 2006, Chemical reviews.

[37]  Xiaoyuan Li,et al.  Polyelectrolyte multilayer as matrix for electrochemical deposition of gold clusters: toward super-hydrophobic surface. , 2004, Journal of the American Chemical Society.

[38]  T. G. Drummond,et al.  Electrochemical DNA sensors , 2003, Nature Biotechnology.

[39]  H. Ju,et al.  Reagentless amperometric immunosensors based on direct electrochemistry of horseradish peroxidase for determination of carcinoma antigen-125. , 2003, Analytical chemistry.

[40]  G. Siest,et al.  Biological variations and genetic reference values for apolipoprotein E serum concentrations: results from the STANISLAS cohort study. , 1998, Clinical chemistry.

[41]  Kevin Taddei,et al.  Increased plasma apolipoprotein E (apoE) levels in Alzheimer's disease , 1997, Neuroscience Letters.

[42]  A. Delacourte,et al.  Relevance of the quantification of apolipoprotein E in the cerebrospinal fluid in Alzheimer's disease , 1996, Neuroscience Letters.

[43]  A D Roses,et al.  APOE is a major susceptibility gene for Alzheimer's disease. , 1994, Current opinion in biotechnology.

[44]  J. Haines,et al.  Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. , 1993, Science.

[45]  K S Kosik,et al.  Alzheimer's disease: a cell biological perspective. , 1992, Science.

[46]  O. Petrii,et al.  Real surface area measurements in electrochemistry , 1991 .

[47]  R. Mahley,et al.  Lipoprotein receptors and cholesterol homeostasis. , 1983, Biochimica et biophysica acta.

[48]  G. Utermann,et al.  Polymorphism of apolipoprotein E and occurrence of dysbetalipoproteinaemia in man , 1977, Nature.

[49]  D. Selkoe Toward a remembrance of things past: deciphering Alzheimer disease. , 2003, Harvey lectures.