Trafficking and signaling by fatty-acylated and prenylated proteins
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[1] C. Thompson,et al. PKC regulates a farnesyl-electrostatic switch on K-Ras that promotes its association with Bcl-XL on mitochondria and induces apoptosis. , 2006, Molecular cell.
[2] C. Ambrose,et al. Identification of a Palmitic Acid-modified Form of Human Sonic hedgehog* , 1998, The Journal of Biological Chemistry.
[3] Robert G. Parton,et al. GTP-dependent segregation of H-ras from lipid rafts is required for biological activity , 2001, Nature Cell Biology.
[4] J. B. Sajous,et al. Ras signalling on the endoplasmic reticulum and the Golgi , 2002, Nature Cell Biology.
[5] M. Seabra,et al. Fatty acylation and prenylation of proteins: what's hot in fat. , 2005, Current opinion in cell biology.
[6] M. Resh,et al. Myristylation and palmitylation of Src family members: The fats of the matter , 1994, Cell.
[7] M. Resh,et al. Palmitoylation of the EGFR ligand Spitz by Rasp increases Spitz activity by restricting its diffusion. , 2006, Developmental cell.
[8] S. Korsmeyer,et al. Posttranslational N-myristoylation of BID as a molecular switch for targeting mitochondria and apoptosis. , 2000, Science.
[9] H. Hofemeister,et al. Association of prenylated proteins with the plasma membrane and the inner nuclear membrane is mediated by the same membrane-targeting motifs. , 2000, Molecular biology of the cell.
[10] Yun Lu,et al. Mass Spectrometric Analysis of GAP-43/Neuromodulin Reveals the Presence of a Variety of Fatty Acylated Species* , 2002, The Journal of Biological Chemistry.
[11] Herbert Waldmann,et al. Structure of Rab GDP-Dissociation Inhibitor in Complex with Prenylated YPT1 GTPase , 2003, Science.
[12] M. Resh,et al. Heterogeneous Fatty Acylation of Src Family Kinases with Polyunsaturated Fatty Acids Regulates Raft Localization and Signal Transduction* , 2001, The Journal of Biological Chemistry.
[13] M. Resh,et al. Rapid Plasma Membrane Anchoring of Newly Synthesized p59 fyn: Selective Requirement for NH2-Terminal Myristoylation and Palmitoylation at Cysteine-3 , 1997, The Journal of cell biology.
[14] D. Bredt,et al. Protein palmitoylation: a regulator of neuronal development and function , 2002, Nature Reviews Neuroscience.
[15] T. Morimoto,et al. Endomembrane Trafficking of Ras The CAAX Motif Targets Proteins to the ER and Golgi , 1999, Cell.
[16] A. Aderem,et al. The myristoyl-electrostatic switch: a modulator of reversible protein-membrane interactions. , 1995, Trends in biochemical sciences.
[17] M. Resh. Fatty acylation of proteins: new insights into membrane targeting of myristoylated and palmitoylated proteins. , 1999, Biochimica et biophysica acta.
[18] N. Ben-Tal,et al. Electrostatics and the membrane association of Src: theory and experiment. , 1998, Biochemistry.
[19] R. Deschenes,et al. Palmitoylation and Plasma Membrane Localization of Ras2p by a Nonclassical Trafficking Pathway in Saccharomyces cerevisiae , 2003, Molecular and Cellular Biology.
[20] M. Resh. Membrane targeting of lipid modified signal transduction proteins. , 2004, Sub-cellular biochemistry.
[21] T. Utsumi,et al. C‐terminal 15 kDa fragment of cytoskeletal actin is posttranslationally N‐myristoylated upon caspase‐mediated cleavage and targeted to mitochondria , 2003, FEBS letters.
[22] A. Gilman,et al. Persistent membrane association of activated and depalmitoylated G protein α subunits , 1999 .
[23] T. Utsumi,et al. Posttranslational N-Myristoylation Is Required for the Anti-apoptotic Activity of Human tGelsolin, the C-terminal Caspase Cleavage Product of Human Gelsolin* , 2006, Journal of Biological Chemistry.
[24] A. Álvarez-Barrientos,et al. N-terminal palmitoylation within the appropriate amino acid environment conveys on NOS2 the ability to progress along the intracellular sorting pathways , 2006, Journal of Cell Science.
[25] J. Hancock,et al. H-ras but Not K-ras Traffics to the Plasma Membrane through the Exocytic Pathway , 2000, Molecular and Cellular Biology.
[26] G. Plummer,et al. Posttranslational myristoylation of caspase-activated p21-activated protein kinase 2 (PAK2) potentiates late apoptotic events. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[27] M. Fukata,et al. Impaired activation and localization of LAT in anergic T cells as a consequence of a selective palmitoylation defect. , 2006, Immunity.
[28] B Honig,et al. Electrostatic interaction of myristoylated proteins with membranes: simple physics, complicated biology. , 1997, Structure.
[29] S. Leppla,et al. Receptor palmitoylation and ubiquitination regulate anthrax toxin endocytosis , 2006, The Journal of cell biology.
[30] R. M. Peitzsch,et al. Binding of acylated peptides and fatty acids to phospholipid vesicles: pertinence to myristoylated proteins. , 1993, Biochemistry.
[31] S. Colombo,et al. N-myristoylation determines dual targeting of mammalian NADH-cytochrome b(5) reductase to ER and mitochondrial outer membranes by a mechanism of kinetic partitioning , 2005, The Journal of cell biology.
[32] Charles D Smith,et al. Two N-Myristoyltransferase Isozymes Play Unique Roles in Protein Myristoylation, Proliferation, and Apoptosis , 2005, Molecular Cancer Research.
[33] R. Leventis,et al. K-ras4B and prenylated proteins lacking "second signals" associate dynamically with cellular membranes. , 2005, Molecular biology of the cell.
[34] T. Meyer,et al. Reversible intracellular translocation of KRas but not HRas in hippocampal neurons regulated by Ca2+/calmodulin , 2005, The Journal of cell biology.
[35] I. Weissman,et al. Wnt proteins are lipid-modified and can act as stem cell growth factors , 2003, Nature.
[36] T. Nakatsu,et al. Crystal structure of a myristoylated CAP‐23/NAP‐22 N‐terminal domain complexed with Ca2+/calmodulin , 2004, The EMBO journal.
[37] M. Bouvier,et al. Role of palmitoylation/depalmitoylation reactions in G-protein-coupled receptor function. , 2003, Pharmacology & therapeutics.
[38] S. Sebti. Protein farnesylation: implications for normal physiology, malignant transformation, and cancer therapy. , 2005, Cancer cell.
[39] M. Marsh,et al. Trafficking of an Acylated Cytosolic Protein: Newly Synthesized p56lck Travels to the Plasma Membrane via the Exocytic Pathway , 1999, The Journal of cell biology.
[40] C. Marshall,et al. A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21 ras to the plasma membrane , 1990, Cell.
[41] Y. Percherancier,et al. Palmitoylation-dependent Control of Degradation, Life Span, and Membrane Expression of the CCR5 Receptor* , 2001, The Journal of Biological Chemistry.
[42] Sebastian Maurer-Stroh,et al. N-terminal N-myristoylation of proteins: prediction of substrate proteins from amino acid sequence. , 2002, Journal of molecular biology.
[43] Gregory R. Hoffman,et al. Structure of the Rho Family GTP-Binding Protein Cdc42 in Complex with the Multifunctional Regulator RhoGDI , 2000, Cell.
[44] R. Leventis,et al. Lipid-modified, cysteinyl-containing peptides of diverse structures are efficiently S-acylated at the plasma membrane of mammalian cells , 1996, The Journal of cell biology.
[45] C. Marshall,et al. All ras proteins are polyisoprenylated but only some are palmitoylated , 1989, Cell.
[46] J. Smotrys,et al. Palmitoylation of intracellular signaling proteins: regulation and function. , 2004, Annual review of biochemistry.
[47] G. Fishell,et al. An acylatable residue of Hedgehog is differentially required in Drosophila and mouse limb development. , 2001, Developmental biology.
[48] P. Weigel,et al. Nonpalmitoylated Human Asialoglycoprotein Receptors Recycle Constitutively but Are Defective in Coated Pit-mediated Endocytosis, Dissociation, and Delivery of Ligand to Lysosomes* , 2002, The Journal of Biological Chemistry.
[49] C. Ungermann,et al. Palmitoylation determines the function of Vac8 at the yeast vacuole , 2006, Journal of Cell Science.
[50] M. Bergo,et al. N-Myristoyltransferase 1 Is Essential in Early Mouse Development* , 2005, Journal of Biological Chemistry.
[51] H. Waldmann,et al. S-Acylation and plasma membrane targeting of the farnesylated carboxyl-terminal peptide of N-ras in mammalian fibroblasts. , 1997, Biochemistry.
[52] Maureen P. Boyle,et al. Palmitoylation regulates plasma membrane–nuclear shuttling of R7BP, a novel membrane anchor for the RGS7 family , 2005, The Journal of cell biology.
[53] Yun Lu,et al. The N-terminal SH4 Region of the Src Family Kinase Fyn Is Modified by Methylation and Heterogeneous Fatty Acylation , 2004, Journal of Biological Chemistry.
[54] Kousuke Kasahara,et al. Trafficking of Lyn through the Golgi caveolin involves the charged residues on αE and αI helices in the kinase domain , 2004, The Journal of cell biology.
[55] J. Lippincott-Schwartz,et al. Depalmitoylated Ras traffics to and from the Golgi complex via a nonvesicular pathway , 2005, The Journal of cell biology.
[56] M. Bouvier,et al. Distinct Subcellular Localization for Constitutive and Agonist-modulated Palmitoylation of the Human δ Opioid Receptor* , 2006, Journal of Biological Chemistry.
[57] Yu Xue,et al. CSS-Palm: palmitoylation site prediction with a clustering and scoring strategy (CSS) , 2006, Bioinform..
[58] J. Gordon,et al. The Biology and Enzymology of ProteinN-Myristoylation* 210 , 2001, The Journal of Biological Chemistry.
[59] Deepti Chaturvedi,et al. Drosophila Wnt-1 Undergoes a Hydrophobic Modification and Is Targeted to Lipid Rafts, a Process That Requires Porcupine* , 2004, Journal of Biological Chemistry.
[60] H. Bourne,et al. Activation-induced subcellular redistribution of Gs alpha. , 1996, Molecular biology of the cell.
[61] L. Xue,et al. A Palmitoylation Switch Mechanism in the Regulation of the Visual Cycle , 2004, Cell.
[62] Robert G. Parton,et al. Direct visualization of Ras proteins in spatially distinct cell surface microdomains , 2003, The Journal of cell biology.
[63] M. Y. Degtyarev,et al. The stoichiometry of G alpha(s) palmitoylation in its basal and activated states. , 1997, Biochemistry.
[64] O. Weisz,et al. Recycling of MUC1 Is Dependent on Its Palmitoylation* , 2006, Journal of Biological Chemistry.
[65] J. Yates,et al. Global Analysis of Protein Palmitoylation in Yeast , 2006, Cell.
[66] H. Waldmann,et al. Membrane insertion of a lipidated ras peptide studied by FTIR, solid-state NMR, and neutron diffraction spectroscopy. , 2003, Journal of the American Chemical Society.
[67] M. Resh,et al. Inhibition of Protein Palmitoylation, Raft Localization, and T Cell Signaling by 2-Bromopalmitate and Polyunsaturated Fatty Acids* , 2000, The Journal of Biological Chemistry.
[68] Karen K. Y. Lam,et al. Palmitoylation by the DHHC protein Pfa4 regulates the ER exit of Chs3 , 2006, The Journal of cell biology.
[69] Kai Simons,et al. Lipid rafts and signal transduction , 2000, Nature Reviews Molecular Cell Biology.
[70] Herbert Waldmann,et al. An Acylation Cycle Regulates Localization and Activity of Palmitoylated Ras Isoforms , 2005, Science.
[71] C. Futter,et al. Farnesyltransferase inhibitors disrupt EGF receptor traffic through modulation of the RhoB GTPase , 2004, Journal of Cell Science.
[72] J. Goldberg,et al. Structural Basis for Activation of ARF GTPase Mechanisms of Guanine Nucleotide Exchange and GTP–Myristoyl Switching , 1998, Cell.
[73] R. Deschenes,et al. Thematic review series: Lipid Posttranslational Modifications. Protein palmitoylation by a family of DHHC protein S-acyltransferases Published, JLR Papers in Press, April 1, 2006. , 2006, Journal of Lipid Research.
[74] L. Ruel,et al. Cholesterol modification is necessary for controlled planar long-range activity of Hedgehog in Drosophila epithelia , 2006, Development.
[75] Neal Sweeney,et al. Synaptic Strength Regulated by Palmitate Cycling on PSD-95 , 2002, Cell.
[76] R. Doms,et al. Palmitoylation of CCR5 Is Critical for Receptor Trafficking and Efficient Activation of Intracellular Signaling Pathways* , 2001, The Journal of Biological Chemistry.
[77] F. L'Heureux,et al. Fluorimetric evaluation of the affinities of isoprenylated peptides for lipid bilayers. , 1994, Biochemistry.
[78] G. Superti-Furga,et al. A Myristoyl/Phosphotyrosine Switch Regulates c-Abl , 2003, Cell.
[79] D. Manning,et al. Regulation of G proteins by covalent modification , 2001, Oncogene.
[80] Suzanne Eaton,et al. Lipoprotein particles are required for Hedgehog and Wingless signalling , 2005, Nature.
[81] D. Murray,et al. Plasma membrane phosphoinositide organization by protein electrostatics , 2005, Nature.
[82] J. Hancock,et al. Three Separable Domains Regulate GTP-Dependent Association of H-ras with the Plasma Membrane , 2004, Molecular and Cellular Biology.
[83] Lu Gan,et al. Palmitoylation of huntingtin by HIP14is essential for its trafficking and function , 2006, Nature Neuroscience.
[84] R. Gibbs,et al. Geranylgeranyl switching regulates GDI-Rab GTPase recycling. , 2003, Structure.
[85] A. Gomes,et al. Membrane targeting of Rab GTPases is influenced by the prenylation motif. , 2003, Molecular biology of the cell.
[86] Barry Honig,et al. Retroviral matrix domains share electrostatic homology: models for membrane binding function throughout the viral life cycle. , 2005, Structure.
[87] E. Krause,et al. Gαs is palmitoylated at the N‐terminal glycine , 2003 .
[88] J. Treisman,et al. Lipid Modification of Secreted Signaling Proteins , 2006, Cell cycle.
[89] T. Asano,et al. Palmitoylation of the canine histamine H2 receptor occurs at Cys(305) and is important for cell surface targeting. , 2001, Biochimica et biophysica acta.
[90] M. Resh,et al. Membrane binding of myristylated peptides corresponding to the NH2 terminus of Src. , 1994, Biochemistry.
[91] M. Resh,et al. Amino-terminal basic residues of Src mediate membrane binding through electrostatic interaction with acidic phospholipids. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[92] Philip A Beachy,et al. Novel lipid modifications of secreted protein signals. , 2004, Annual review of biochemistry.
[93] G. Milligan,et al. Palmitoylation Regulates Regulator of G-protein Signaling (RGS) 16 Function , 2003, Journal of Biological Chemistry.
[94] Peter J. Cullen,et al. Phospholipase Cγ activates Ras on the Golgi apparatus by means of RasGRP1 , 2003, Nature.
[95] M Ikura,et al. Portrait of a myristoyl switch protein. , 1996, Current opinion in structural biology.