Dental and Facial Characteristics in Down's Syndrome (Mongolism)

further natural experiment bearing on dental and facial growth. Agenesis of J2 and other teeth is common, but the incidence of number reduction in the parents needs to be known. Abnormalities in tooth formation timing has been suggested. Ideally, the unaffected siblings should be used as controls. Growth of the skull base and face is characteristically altered, providing an opportunity to test cephalometric parameters. Besides the interest in chromosomal abnormality itself, Down's disease, that is, "Mongolism," has great potential bearing on the determinants of normal dentofacial development. -S. M. G.

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