Magnetic resonance imaging of the normal canine eye using a T1-weighted volumetric acquisition.

PURPOSE MRI is becoming increasingly available within the veterinary profession, and eyes are frequently included as part of a cranial study. The advantages of volumetric imaging are numerous, when compared to traditional two-dimensional imaging, and could be utilised within the veterinary setting. This report describing the normal MRI appearance of the canine eye, aimed to establish a standard reference range on a T1w volumetric acquisition. METHOD This study retrospectively assessed 62 eyes from 31 dogs that had undergone MRI at the Small Animal Hospital, Langford Vets, University of Bristol between 2016 and 2018 using a standardised MRI protocol. Dogs were excluded if they had presented with any reported ocular or orbital abnormalities. Measurements were performed from the 3D T1w volumetric sequence by a single observer using a previously published technique. RESULTS Mean axial globe length was 2.13 cm and equatorial width 2.16 cm. Mean anteroposterior depth of the anterior chamber was 0.40 cm and 0.97 cm for the vitreous chamber. The mean anteroposterior and equatorial distance of the lens was 0.75 cm and 1.15 cm, respectively. Mean optic nerve width was 0.15 cm, and the mean width of the entire optic nerve sheath was 0.43 cm. Statistically significant relationships were noted between age and axial globe length and both lens dimensions. Highly significant relationships were noted between all variables, except lens dimensions and body weight CONCLUSION: This study provides reference values to assist in the interpretation of ocular structures during MRI on a T1w volumetric acquisition.

[1]  T. Maddox,et al.  Three‐dimensional T1‐weighted gradient echo is a suitable alternative to two‐dimensional T1‐weighted spin echo for imaging the canine brain , 2019, Veterinary Radiology & Ultrasound.

[2]  A. zur Linden,et al.  Computed tomography measurements of intraocular structures of the feline eye , 2019, Veterinary Record.

[3]  A. M. Adrian,et al.  Magnetic resonance imaging findings in dogs with orbital inflammation , 2018, The Journal of small animal practice.

[4]  T. Nakazawa,et al.  Quantitative MRI evaluation of glaucomatous changes in the visual pathway , 2018, PloS one.

[5]  J. Bloem,et al.  MR signal intensity: staying on the bright side in MR image interpretation , 2018, RMD Open.

[6]  L. De Risio,et al.  Ischemic Optic Neuropathy in a Dog with Acute Bilateral Blindness and Primary Systemic Hypertension , 2017, Journal of veterinary internal medicine.

[7]  J. Estroff,et al.  Normative biometrics for fetal ocular growth using volumetric MRI reconstruction , 2015, Prenatal diagnosis.

[8]  M. Herrtage,et al.  CT dimensions, volumes and densities of normal canine eyes , 2015, Veterinary Record.

[9]  H. Erb,et al.  T2-weighted magnetic resonance imaging measurements of optic nerve sheath diameter in dogs with and without presumed intracranial hypertension. , 2013, Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association.

[10]  Natalie J. Blades,et al.  A review of orbital and intracranial magnetic resonance imaging in 79 canine and 13 feline patients (2004-2010). , 2011, Veterinary ophthalmology.

[11]  A. Malhotra,et al.  Ocular anatomy and cross-sectional imaging of the eye. , 2011, Seminars in ultrasound, CT, and MR.

[12]  M. Leiva,et al.  Acute postretinal blindness: ophthalmologic, neurologic, and magnetic resonance imaging findings in dogs and cats (seven cases). , 2010, Veterinary ophthalmology.

[13]  G. Voorhout,et al.  Magnetic resonance imaging of the canine optic nerve. , 2008, Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association.

[14]  C. LeBedis,et al.  Nontraumatic orbital conditions: diagnosis with CT and MR imaging in the emergent setting. , 2008, Radiographics : a review publication of the Radiological Society of North America, Inc.

[15]  R. Dennis Imaging features of orbital myxosarcoma in dogs. , 2008, Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association.

[16]  G. Daniel,et al.  Cross-sectional imaging techniques in veterinary ophthalmology. , 2001, Clinical techniques in small animal practice.

[17]  R. Dennis Use of magnetic resonance imaging for the investigation of orbital disease in small animals. , 2000, The Journal of small animal practice.

[18]  R. Donnell,et al.  MAGNETIC RESONANCE IMAGING OF THE NORMAL EYE AND ORBIT OF THE DOG AND CAT , 1994 .

[19]  M. L. Wood,et al.  FLASH: clinical three-dimensional magnetic resonance imaging. , 1988, Radiographics : a review publication of the Radiological Society of North America, Inc.