Force transmission in migrating cells

Analysis of the relationship between actin network velocity and traction forces at the substrate shows that force transmission mechanisms vary with distinct regions of the cell.

[1]  L. Cramer,et al.  Molecular mechanism of actin-dependent retrograde flow in lamellipodia of motile cells. , 1997, Frontiers in bioscience : a journal and virtual library.

[2]  M. Dembo,et al.  Stresses at the cell-to-substrate interface during locomotion of fibroblasts. , 1999, Biophysical journal.

[3]  W. Loomis,et al.  Cell motility and chemotaxis in Dictyostelium amebae lacking myosin heavy chain. , 1988, Developmental biology.

[4]  C. Verdier,et al.  Traction patterns of tumor cells , 2009, Journal of mathematical biology.

[5]  T. Mitchison,et al.  Comparison of actin and cell surface dynamics in motile fibroblasts , 1992, The Journal of cell biology.

[6]  T. Mitchison,et al.  Actin-Based Cell Motility and Cell Locomotion , 1996, Cell.

[7]  Hiroshi Hosoya,et al.  Traction forces of fibroblasts are regulated by the Rho-dependent kinase but not by the myosin light chain kinase. , 2006, Archives of biochemistry and biophysics.

[8]  K. Jacobson,et al.  The composition and dynamics of cell-substratum adhesions in locomoting fish keratocytes. , 1997, Journal of cell science.

[9]  David J Odde,et al.  Traction Dynamics of Filopodia on Compliant Substrates , 2008, Science.

[10]  K. Jacobson,et al.  The fish epidermal keratocyte as a model system for the study of cell locomotion. , 1993, Symposia of the Society for Experimental Biology.

[11]  G. Borisy,et al.  Cell Migration: Integrating Signals from Front to Back , 2003, Science.

[12]  Andrew D. Doyle,et al.  Simultaneous, real-time imaging of intracellular calcium and cellular traction force production. , 2002, BioTechniques.

[13]  Robert E. Buxbaum,et al.  Cell Crawling: First the Motor, Now the Transmission , 1998, The Journal of cell biology.

[14]  Josef A. Käs,et al.  Cell migration through small gaps , 2006, European Biophysics Journal.

[15]  Yoshiaki Iwadate,et al.  Actin-based propulsive forces and myosin-II-based contractile forces in migrating Dictyostelium cells , 2008, Journal of Cell Science.

[16]  Gaudenz Danuser,et al.  Actin–myosin network reorganization breaks symmetry at the cell rear to spontaneously initiate polarized cell motility , 2007, The Journal of cell biology.

[17]  George Oster,et al.  Polymer Motors: Pushing out the Front and Pulling up the Back , 2003, Current Biology.

[18]  Manfred Radmacher,et al.  Direct measurement of the lamellipodial protrusive force in a migrating cell , 2006, The Journal of cell biology.

[19]  G. Danuser,et al.  Locomotion of fish epidermal keratocytes on spatially selective adhesion patterns. , 2007, Cell motility and the cytoskeleton.

[20]  Michael P. Sheetz,et al.  Keratocytes Pull with Similar Forces on Their Dorsal and Ventral Surfaces , 1999, The Journal of cell biology.

[21]  Chun-Min Lo,et al.  Nonmuscle myosin IIb is involved in the guidance of fibroblast migration. , 2003, Molecular biology of the cell.

[22]  Gary G. Borisy,et al.  Analysis of the Actin–Myosin II System in Fish Epidermal Keratocytes: Mechanism of Cell Body Translocation , 1997, The Journal of cell biology.

[23]  M. Sixt,et al.  Rapid leukocyte migration by integrin-independent flowing and squeezing , 2008, Nature.

[24]  Julie A. Theriot,et al.  Mechanism of shape determination in motile cells , 2008, Nature.

[25]  S. Maciver.  Myosin II function in non-muscle cells. , 1996, BioEssays : news and reviews in molecular, cellular and developmental biology.

[26]  Jean-Jacques Meister,et al.  Comparative maps of motion and assembly of filamentous actin and myosin II in migrating cells. , 2007, Molecular biology of the cell.

[27]  Micah Dembo,et al.  Traction force microscopy in Dictyostelium reveals distinct roles for myosin II motor and actin-crosslinking activity in polarized cell movement , 2007, Journal of Cell Science.

[28]  Micah Dembo,et al.  Separation of Propulsive and Adhesive Traction Stresses in Locomoting Keratocytes , 1999, The Journal of cell biology.

[29]  Kurt I. Anderson,et al.  Contact dynamics during keratocyte motility , 2000, Current Biology.

[30]  J. Small,et al.  Coordination of protrusion and translocation of the keratocyte involves rolling of the cell body , 1996, The Journal of cell biology.

[31]  Ken Jacobson,et al.  Actin-myosin viscoelastic flow in the keratocyte lamellipod. , 2009, Biophysical journal.

[32]  Marie-France Carlier,et al.  Mechanism of Actin-Based Motility , 2001, Science.

[33]  Gaudenz Danuser,et al.  Differential Transmission of Actin Motion Within Focal Adhesions , 2007, Science.

[34]  L. Smilenov,et al.  Focal adhesion motility revealed in stationary fibroblasts. , 1999, Science.

[35]  D. Ambrosi,et al.  Cellular Traction as an Inverse Problem , 2006, SIAM J. Appl. Math..

[36]  Joe Tien,et al.  Mechanotransduction at cell-matrix and cell-cell contacts. , 2004, Annual review of biomedical engineering.

[37]  A. Mogilner,et al.  Weak force stalls protrusion at the leading edge of the lamellipodium. , 2006, Biophysical journal.

[38]  Benjamin Geiger,et al.  Exploring the Neighborhood Adhesion-Coupled Cell Mechanosensors , 2002, Cell.

[39]  Miguel Vicente-Manzanares,et al.  Segregation and activation of myosin IIB creates a rear in migrating cells , 2008, The Journal of cell biology.

[40]  Juliet Lee,et al.  Slipping or gripping? Fluorescent speckle microscopy in fish keratocytes reveals two different mechanisms for generating a retrograde flow of actin. , 2004, Molecular biology of the cell.

[41]  Yu-li Wang.  Flux at Focal Adhesions: Slippage Clutch, Mechanical Gauge, or Signal Depot , 2007, Science's STKE.

[42]  T. Svitkina,et al.  Network contraction model for cell translocation and retrograde flow. , 1999, Biochemical Society symposium.

[43]  T. Pollard,et al.  Cellular Motility Driven by Assembly and Disassembly of Actin Filaments , 2003, Cell.

[44]  Gaudenz Danuser,et al.  Traction stress in focal adhesions correlates biphasically with actin retrograde flow speed , 2008, The Journal of cell biology.