Substance Abuse Disorder and Major Depression are Associated with the Human 5-HT1B Receptor Gene (HTR1B) G861C Polymorphism

[1]  J. Mann Neurobiology of suicidal behaviour , 2003, Nature Reviews Neuroscience.

[2]  D. Brent,et al.  Suicidal Behavior Runs in Families , 2002 .

[3]  J. Gelernter,et al.  Polymorphism of the 5-HT1B Receptor Gene (HTR1B): Strong Within-Locus Linkage Disequilibrium without Association to Antisocial Substance Dependence , 2002, Neuropsychopharmacology.

[4]  E. Mundo,et al.  The 5HT1Dβ Receptor Gene in Bipolar Disorder: A Family-based Association Study , 2001, Neuropsychopharmacology.

[5]  H. Ono,et al.  No evidence of an association between 5HT1B receptor gene polymorphism and suicide victims in a Japanese population. , 2001, American journal of medical genetics.

[6]  N. Dahmen,et al.  The HTR1B 861G>C receptor polymorphism among patients suffering from alcoholism, major depression, anxiety disorders and narcolepsy , 2000, Psychiatry Research.

[7]  V. Arango,et al.  Relationship of Psychopathology to the Human Serotonin1B Genotype and Receptor Binding Kinetics in Postmortem Brain Tissue , 1999, Neuropsychopharmacology.

[8]  J John Mann,et al.  Role of the Serotonergic System in the Pathogenesis of Major Depression and Suicidal Behavior , 1999, Neuropsychopharmacology.

[9]  R. Hen,et al.  5‐HT Receptor Knockout Mice: Pharmacological Tools or Models of Psychiatric Disorders , 1999, Annals of the New York Academy of Sciences.

[10]  C Waternaux,et al.  Toward a clinical model of suicidal behavior in psychiatric patients. , 1999, The American journal of psychiatry.

[11]  Gerald L. Brown,et al.  Linkage of antisocial alcoholism to the serotonin 5-HT1B receptor gene in 2 populations. , 1998, Archives of general psychiatry.

[12]  A. Bergen,et al.  General and specific inheritance of substance abuse and alcoholism. , 1998, Archives of general psychiatry.

[13]  M. Tsuang,et al.  Co-occurrence of abuse of different drugs in men: the role of drug-specific and shared vulnerabilities. , 1998, Archives of general psychiatry.

[14]  Beth E. Molnar,et al.  Comorbidity of substance use disorders with mood and anxiety disorders: results of the International Consortium in Psychiatric Epidemiology. , 1998, Addictive behaviors.

[15]  L. Bierut,et al.  Familial transmission of substance dependence: alcohol, marijuana, cocaine, and habitual smoking: a report from the Collaborative Study on the Genetics of Alcoholism. , 1998, Archives of general psychiatry.

[16]  R. Hen,et al.  Increased vulnerability to cocaine in mice lacking the serotonin-1B receptor , 1998, Nature.

[17]  C. Katona,et al.  5-HT1D and 5-HT1E/1F binding sites in depressed suicides: increased 5-HT1D binding in globus pallidus but not cortex , 1997, Molecular Psychiatry.

[18]  D. Brent,et al.  Suicidal behavior runs in families. A controlled family study of adolescent suicide victims. , 1996, Archives of general psychiatry.

[19]  R. Hen,et al.  Elevated alcohol consumption in null mutant mice lacking 5–HT1B serotonin receptors , 1996, Nature Genetics.

[20]  M. Buhot,et al.  5-HT1B receptor knock out — behavioral consequences , 1995, Behavioural Brain Research.

[21]  D. Goldman,et al.  Mapping of the serotonin 5-HT1D beta autoreceptor gene on chromosome 6 and direct analysis for sequence variants. , 1995, American journal of medical genetics.

[22]  R Hen,et al.  Enhanced aggressive behavior in mice lacking 5-HT1B receptor. , 1994, Science.

[23]  J. Marcusson,et al.  Brain 5-HT1A, 5-HT1D, and 5-HT2 Receptors in suicide victims , 1994, Biological Psychiatry.

[24]  M. Nöthen,et al.  Identification of genetic variation in the human serotonin 1D beta receptor gene. , 1994, Biochemical and biophysical research communications.

[25]  C. Nemeroff,et al.  CSF biochemistries, glucose metabolism, and diurnal activity rhythms in alcoholic, violent offenders, fire setters, and healthy volunteers. , 1994, Archives of general psychiatry.

[26]  J. Kennedy,et al.  New polymorphism for the human serotonin 1D receptor variant (5-HT1D beta) not linked to schizophrenia in five Canadian pedigrees. , 1993, Human heredity.

[27]  M. Raiteri,et al.  Release‐Regulating Serotonin 5‐HT1D Autoreceptors in Human Cerebral Cortex , 1993, Journal of neurochemistry.

[28]  G. Gyapay,et al.  A second-generation linkage map of the human genome , 1992, Nature.

[29]  A. Roy Suicide in Twins , 1986, Archives of general psychiatry.

[30]  Henry A. Erlich,et al.  PCR Technology: Principles and Applications for DNA Amplification , 1989 .

[31]  J. Nurnberger,et al.  Genetic Studies of Affective Illness , 1989 .

[32]  R. Higuchi,et al.  Simple and Rapid Preparation of Samples for PCR , 1989 .

[33]  A. Roy Genetics of Suicide , 1986 .

[34]  Ting-kai Li,et al.  University of California, Davis–Conference: Genetics of Alcoholism , 1985 .

[35]  M. Schuckit,et al.  The Genetics of Alcoholism , 1983 .

[36]  F. Goodwin,et al.  5-hydroxytryptamine and depression: a model for the interaction of normal variance with pathology. , 1983, British journal of clinical pharmacology.

[37]  Gerald L. Brown,et al.  Alcohol and central serotonin metabolism in man. , 1979, Archives of general psychiatry.

[38]  P. Armitage Tests for Linear Trends in Proportions and Frequencies , 1955 .