Aim: Compare tissue grafting from autologous and allogenous sources for the treatment of
Seibert Class I border defects. Methods: 18 surgical sites from 14 patients were selected and
randomly assigned. 8 surgical sites received connective tissue grafts from autologous donor
sites, and 9 surgical sites received allogenous muscular fascia grafts. 4 diagnostic casts were
taken for comparative study (baseline, 1 month, 2nd month and 4th month postsurgical). In
addition, 6 tissue punch biopsies were taken from the fascia group to determine presence of
fascia tissue. Results: The control group showed an average tissue depth of 2.29 ± 0.55 mm
and the experimental group showed 3.5 ± 0.85 mm, at baseline. Tissue gain for the fascia
group was 71.2%, 46.52% y 28.5% for the 1st, 2nd and 4th months respectively, and the
control group presented 56.53%, 38.31% y 38.1% respectively. There were not statistically
significant differences between the two treatments (p>0,05). Histological analysis of the fascia
group showed dense collagen tissue and host connective tissue at the 4th month. Fascia
tissue grafts seemed to reabsorb faster than the connective tissue from the control group
and the gain in tissue size at the 4th month was similar in both groups. The fascia tissue
group, however, seemed to present less morbidity and was found in the histological samples
at the 20 week postsurgical measurements. The connective tissue grafts were more stable in
the treatment of Seibert I border defects. Conclusions: Human muscular fascia tissue could
be an alternative treatment for the correction of Seibert class I border defects.
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