Blastocyst-like structures generated solely from stem cells

[1]  N. Rivron.  Formation of blastoids from mouse embryonic and trophoblast stem cells , 2018 .

[2]  Christos Kyprianou,et al.  Assembly of embryonic and extraembryonic stem cells to mimic embryogenesis in vitro , 2017, Science.

[3]  Mauro J. Muraro,et al.  A Single-Cell Transcriptome Atlas of the Human Pancreas , 2016, Cell systems.

[4]  M. Hemberger,et al.  From the stem of the placental tree: trophoblast stem cells and their progeny , 2016, Development.

[5]  Jeroen Rouwkema,et al.  Directed Assembly and Development of Material‐Free Tissues with Complex Architectures , 2016, Advanced materials.

[6]  Shuqiang Li,et al.  CEL-Seq2: sensitive highly-multiplexed single-cell RNA-Seq , 2016, Genome Biology.

[7]  R K Truckenmüller,et al.  3D high throughput screening and profiling of embryoid bodies in thermoformed microwell plates. , 2016, Lab on a chip.

[8]  Aleksandra A. Kolodziejczyk,et al.  Single Cell RNA-Sequencing of Pluripotent States Unlocks Modular Transcriptional Variation , 2015, Cell stem cell.

[9]  Dahai Liu,et al.  Klf2 and Tfcp2l1, Two Wnt/β-Catenin Targets, Act Synergistically to Induce and Maintain Naive Pluripotency , 2015, Stem cell reports.

[10]  Hans Clevers,et al.  Single-cell messenger RNA sequencing reveals rare intestinal cell types , 2015, Nature.

[11]  K. Sekiguchi,et al.  SC3-seq: a method for highly parallel and quantitative measurement of single-cell gene expression , 2015, Nucleic acids research.

[12]  J. Cross,et al.  Three-dimensional cultures of trophoblast stem cells autonomously develop vascular-like spaces lined by trophoblast giant cells. , 2015, Developmental biology.

[13]  C. Papanayotou,et al.  Activin/Nodal signalling before implantation: setting the stage for embryo patterning , 2014, Philosophical Transactions of the Royal Society B: Biological Sciences.

[14]  Sonja Nowotschin,et al.  Symmetry breaking, germ layer specification and axial organisation in aggregates of mouse embryonic stem cells , 2014, Development.

[15]  M. Araúzo-Bravo,et al.  Derivation and Maintenance of Murine Trophoblast Stem Cells under Defined Conditions , 2014, Stem cell reports.

[16]  Wolfgang Huber,et al.  Cell-to-cell expression variability followed by signal reinforcement progressively segregates early mouse lineages , 2013, Nature Cell Biology.

[17]  A. Sharov,et al.  Totipotent Embryonic Stem Cells Arise in Ground-State Culture Conditions , 2013, Cell reports.

[18]  François Nédélec,et al.  A self-organization framework for symmetry breaking in the mammalian embryo , 2013, Nature Reviews Molecular Cell Biology.

[19]  Yixian Zheng,et al.  Generation and live imaging of an endogenous Cdx2 reporter mouse line , 2012, Genesis.

[20]  T. Hashimshony,et al.  CEL-Seq: single-cell RNA-Seq by multiplexed linear amplification. , 2012, Cell reports.

[21]  Roman K Truckenmüller,et al.  Tissue deformation spatially modulates VEGF signaling and angiogenesis , 2012, Proceedings of the National Academy of Sciences.

[22]  M. McConaha,et al.  Microarray assessment of the influence of the conceptus on gene expression in the mouse uterus during decidualization. , 2011, Reproduction.

[23]  D. Constam,et al.  Imaging proprotein convertase activities and their regulation in the implanting mouse blastocyst , 2010, The Journal of cell biology.

[24]  W. Huber,et al.  which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. MAnorm: a robust model for quantitative comparison of ChIP-Seq data sets , 2011 .

[25]  Israel Steinfeld,et al.  BMC Bioinformatics BioMed Central , 2008 .

[26]  Anna-Katerina Hadjantonakis,et al.  Distinct sequential cell behaviours direct primitive endoderm formation in the mouse blastocyst , 2008, Development.

[27]  B. Doble,et al.  The ground state of embryonic stem cell self-renewal , 2008, Nature.

[28]  Janet Rossant,et al.  Cdx2 acts downstream of cell polarization to cell-autonomously promote trophectoderm fate in the early mouse embryo. , 2008, Developmental biology.

[29]  R. McKay,et al.  New cell lines from mouse epiblast share defining features with human embryonic stem cells , 2007, Nature.

[30]  J. Cross,et al.  Diverse subtypes and developmental origins of trophoblast giant cells in the mouse placenta. , 2007, Developmental biology.

[31]  S. Friedman,et al.  E-cadherin is a novel transcriptional target of the KLF6 tumor suppressor , 2006, Oncogene.

[32]  S. Friedman,et al.  Developmental regulation of yolk sac hematopoiesis by Kruppel-like factor 6. , 2006, Blood.

[33]  E. Willems,et al.  Expression of all Wnt genes and their secreted antagonists during mouse blastocyst and postimplantation development , 2005, Developmental dynamics : an official publication of the American Association of Anatomists.

[34]  K. Manova,et al.  The Docking Protein FRS2α Is an Essential Component of Multiple Fibroblast Growth Factor Responses during Early Mouse Development , 2005, Molecular and Cellular Biology.

[35]  K. Red-Horse,et al.  Trophoblast differentiation during embryo implantation and formation of the maternal-fetal interface. , 2004, The Journal of clinical investigation.

[36]  Christian Sirard,et al.  Smad4 and β-Catenin Co-activators Functionally Interact with Lymphoid-enhancing Factor to Regulate Graded Expression of Msx2* , 2003, Journal of Biological Chemistry.

[37]  S. Meloche,et al.  An essential function of the mitogen‐activated protein kinase Erk2 in mouse trophoblast development , 2003, EMBO reports.

[38]  Brad T. Sherman,et al.  DAVID: Database for Annotation, Visualization, and Integrated Discovery , 2003, Genome Biology.

[39]  Hans Clevers,et al.  The β-Catenin/TCF-4 Complex Imposes a Crypt Progenitor Phenotype on Colorectal Cancer Cells , 2002, Cell.

[40]  R. Gardner.  Flow of cells from polar to mural trophectoderm is polarized in the mouse blastocyst. , 2000, Human reproduction.

[41]  J. Rossant,et al.  Promotion of trophoblast stem cell proliferation by FGF4. , 1998, Science.

[42]  J. Heath,et al.  Targeted disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[43]  R. Schultz,et al.  Development of activatable adenylate cyclase in the preimplantation mouse embryo and a role for cyclic AMP in blastocoel formation , 1986, Cell.

[44]  S. Barton,et al.  Origin of the ectoplacental cone and secondary giant cells in mouse blastocysts reconstituted from isolated trophoblast and inner cell mass. , 1973, Journal of embryology and experimental morphology.

[45]  A. Tarkowski,et al.  Development of blastomeres of mouse eggs isolated at the 4- and 8-cell stage. , 1967, Journal of embryology and experimental morphology.

[46]  Steven Gallinger,et al.  Transcriptional cooperation between the transforming growth factor-beta and Wnt pathways in mammary and intestinal tumorigenesis. , 2007, Cancer research.