Cerebral perfusion changes in presymptomatic genetic frontotemporal dementia: a GENFI study

Imaging biomarkers are needed to detect early brain changes in presymptomatic carriers harbouring FTD mutations. Using arterial spin labelling-MRI, Mutsaerts, Mirza et al. identify an inverse association between cerebral perfusion in frontotemporoparietal regions and expected age of onset. Cerebral perfusion may be a promising imaging biomarker for presymptomatic genetic FTD.

Veronica Redaelli | Sebastien Ourselin | Martina Bocchetta | Nick C Fox | Michela Pievani | Sandro Sorbi | Vesna Jelic | Barbara Borroni | Alessandro Padovani | Sandra E Black | Jan Petr | Giuliano Binetti | Bradley J MacIntosh | Morris Freedman | Maria Carmela Tartaglia | Robert Laforce | Marina Grisoli | Alexandre de Mendonça | James B Rowe | Zahra Shirzadi | Mario Masellis | Luisa Benussi | Roberta Ghidoni | Ekaterina Rogaeva | Elizabeth Finger | Ana Verdelho | Stefano Gazzina | Carolina Maruta | Giovanni B Frisoni | Enrico Premi | Fabrizio Tagliavini | Martin N Rossor | Maura Cosseddu | Silvana Archetti | Daniela Galimberti | Caroline Graff | Cristina Polito | Andrew D Robertson | Enrico de Vita | Ron Keren | M. Freedman | S. Black | S. Ourselin | R. Keren | G. Frisoni | J. Rowe | M. Rossor | S. Mead | E. de Vita | D. Thomas | S. Sorbi | B. Nacmias | D. Galimberti | M. Pievani | M. Bocchetta | J. Rohrer | C. Fenoglio | E. Scarpini | P. Tiraboschi | D. Cash | B. MacIntosh | J. Warren | E. Rogaeva | C. Graff | C. Polito | V. Jelic | G. Binetti | R. Laforce | M. Tartaglia | K. Dick | J. V. van Swieten | B. Borroni | M. Masellis | F. Tagliavini | E. Finger | A. de Mendonça | A. Padovani | V. Redaelli | Andrew Donald Robertson | L. Benussi | R. Ghidoni | A. Metcalfe | Linn Öijerstedt | G. Rossi | M. Grisoli | R. Rademakers | S. Prioni | D. Tang‐Wai | A. Verdelho | C. Maruta | L. Jiskoot | Zahra Shirzadi | S. Mirza | S. Archetti | H. Thonberg | J. Petr | H. Mutsaerts | E. Premi | S. Gazzina | J. Panman | G. Fumagalli | Rosa Rademakers | David L Thomas | Arron W. S. Metcalfe | S. Mitchell | Pietro Tiraboschi | Elio Scarpini | Hakan Thonberg | Jason D Warren | Simon Mead | Benedetta Nacmias | M. Cosseddu | Jonathan D Rohrer | Chiara Fenoglio | Giacomina Rossi | David M Cash | L. Meeter | Christin Silvana Andrea Luisa Giuliano Maura Katrina M Mari Andersson Archetti Arighi Benussi Binett | C. Andersson | A. Arighi | M. Fallström | Carlos Ferreira | G. Lombardi | R. van Minkelen | Henri J M M Mutsaerts | Saira S Mirza | Arron W S Metcalfe | Sara B Mitchell | David Tang-Wai | John van Swieten | Christin Andersson | Andrea Arighi | Katrina M Dick | Marie Fallström | Carlos Ferreira | Giorgio Fumagalli | Lize Jiskoot | Gemma Lombardi | Lieke Meeter | Rick van Minkelen | Linn Öijerstedt | Jessica Panman | Sara Prioni | S. Black | R. Rademakers | C. Ferreira | Christin Andersson | H. Mutsaerts

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