A Novel Therapeutic Peptide as a Partial Agonist of RANKL in Ischemic Stroke

[1]  Divyendu Singh,et al.  LL-37 Peptide Enhancement of Signal Transduction by Toll-like Receptor 3 Is Regulated by pH , 2014, The Journal of Biological Chemistry.

[2]  R. Morishita,et al.  OPG/RANKL/RANK axis is a critical inflammatory signaling system in ischemic brain in mice , 2014, Proceedings of the National Academy of Sciences.

[3]  Á. Chamorro,et al.  Safety and efficacy of uric acid in patients with acute stroke (URICO-ICTUS): a randomised, double-blind phase 2b/3 trial , 2014, The Lancet Neurology.

[4]  G. Hankey,et al.  Intravenous Minocycline in Acute Stroke: A Randomized, Controlled Pilot Study and Meta-analysis , 2013, Stroke.

[5]  M. Kawakami.  Molecular Dissection of Cyclosporin A’s Neuroprotective Effect Reveals Potential Therapeutics for Ischemic Brain Injury , 2013, Brain sciences.

[6]  S. Im,et al.  Ischemic Stroke in Rats Enhances Bone Resorption in Vitro , 2011, Journal of Korean medical science.

[7]  Ming Liu,et al.  Edaravone for acute ischaemic stroke. , 2011, The Cochrane database of systematic reviews.

[8]  V. Berezin,et al.  Neuroplastin‐65 and a mimetic peptide derived from its homophilic binding site modulate neuritogenesis and neuronal plasticity , 2011, Journal of neurochemistry.

[9]  C. Iadecola,et al.  The immunology of stroke: from mechanisms to translation , 2011, Nature Medicine.

[10]  S. Michalek,et al.  TLR2-dependent Modulation of Osteoclastogenesis by Porphyromonas gingivalis through Differential Induction of NFATc1 and NF-κB* , 2011, The Journal of Biological Chemistry.

[11]  S. Ferrari-Lacraz,et al.  Do RANKL inhibitors (denosumab) affect inflammation and immunity? , 2011, Osteoporosis International.

[12]  K. Larsen,et al.  Myocardial Infarction and Risk of Suicide: A Population-Based Case-Control Study , 2010, Circulation.

[13]  M. Chopp,et al.  Thymosin β4 improves functional neurological outcome in a rat model of embolic stroke , 2010, Neuroscience.

[14]  M. M. Soundarapandian,et al.  DAPK1 Interaction with NMDA Receptor NR2B Subunits Mediates Brain Damage in Stroke , 2010, Cell.

[15]  A. Haeseler,et al.  Central control of fever and female body temperature by RANKL/RANK , 2009, Nature.

[16]  Frank de Vries,et al.  Risk of Hip/Femur Fracture After Stroke: A Population-Based Case-Control Study , 2009, Stroke.

[17]  N. Udagawa,et al.  Evaluation of Pharmaceuticals With a Novel 50‐Hour Animal Model of Bone Loss , 2009, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[18]  Ping Zhou,et al.  The Neuroprotective Effect of Prostaglandin E2 EP1 Receptor Inhibition has a Wide Therapeutic Window, is Sustained in Time and is not Sexually Dimorphic , 2009, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[19]  T. Ogihara,et al.  Angiotensin II accelerates osteoporosis by activating osteoclasts , 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[20]  J. Penninger,et al.  Receptor Activator of NF-κB Ligand and Osteoprotegerin Regulate Proinflammatory Cytokine Production in Mice1 , 2006, The Journal of Immunology.

[21]  Ning Zhang,et al.  Edaravone Reduces Early Accumulation of Oxidative Products and Sequential Inflammatory Responses After Transient Focal Ischemia in Mice Brain , 2005, Stroke.

[22]  W. Low,et al.  Synthetic fibronectin peptide exerts neuroprotective effects on transient focal brain ischemia in rats , 2005, Brain Research.

[23]  V. Berezin,et al.  Post-training administration of a synthetic peptide ligand of the neural cell adhesion molecule, C3d, attenuates long-term expression of contextual fear conditioning , 2003, Neuroscience.

[24]  Kevin D Burris,et al.  Aripiprazole, a Novel Antipsychotic, Is a High-Affinity Partial Agonist at Human Dopamine D2 Receptors , 2002, Journal of Pharmacology and Experimental Therapeutics.

[25]  C. Nelson,et al.  Crystal structure of the TRANCE/RANKL cytokine reveals determinants of receptor-ligand specificity. , 2001, The Journal of clinical investigation.

[26]  Yoshihiro Sato,et al.  Influence of immobilization upon calcium metabolism in the week following hemiplegic stroke , 2000, Journal of the Neurological Sciences.

[27]  A. Skubitz,et al.  Laminin Peptide Ameliorates Brain Injury by Inhibiting Leukocyte Accumulation in a Rat Model of Transient Focal Cerebral Ischemia , 1997, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[28]  P. Camarata,et al.  Neuronal Protection from Cerebral Ischemia by Synthetic Fibronectin Peptides to Leukocyte Adhesion Molecules , 1996, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[29]  J. Cornish,et al.  Mutations within the TNF-like core domain of RANKL impair osteoclast differentiation and activation. , 2009, Molecular endocrinology.