Selection of peptomeric inhibitors of bovine α-chymotrypsin and cathepsin G based on trypsin inhibitor SFTI-1 using a combinatorial chemistry approach

[1]  A. Lesner,et al.  Design of selective substrates of proteinase 3 using combinatorial chemistry methods. , 2008, Analytical biochemistry.

[2]  A. Jaśkiewicz,et al.  Design of serine proteinase inhibitors by combinatorial chemistry using trypsin inhibitor SFTI‐1 as a starting structure , 2007, Journal of peptide science : an official publication of the European Peptide Society.

[3]  A. Jaśkiewicz,et al.  New chromogenic substrates of human neutrophil cathepsin G containing non-natural aromatic amino acid residues in position P1 selected by combinatorial chemistry methods , 2007, Molecular Diversity.

[4]  A. Lesner,et al.  Selection of new chromogenic substrates of serine proteinases using combinatorial chemistry methods. , 2007, Combinatorial chemistry & high throughput screening.

[5]  S. Yaliraki,et al.  Role of rigidity on the activity of proteinase inhibitors and their peptide mimics. , 2006, The journal of physical chemistry. B.

[6]  Norelle L Daly,et al.  The Absolute Structural Requirement for a Proline in the P3′-position of Bowman-Birk Protease Inhibitors Is Surmounted in the Minimized SFTI-1 Scaffold* , 2006, Journal of Biological Chemistry.

[7]  A. Jaśkiewicz,et al.  Examples of Peptide–Peptoid Hybrid Serine Protease Inhibitors Based on the Trypsin Inhibitor SFTI‐1 with Complete Protease Resistance at the P1P1′ Reactive Site , 2005, Chembiochem : a European journal of chemical biology.

[8]  Horst Joachim Schirra,et al.  Sunflower trypsin inhibitor-1. , 2004, Current protein & peptide science.

[9]  S. Østergaard,et al.  Peptomers: A Versatile Approach for the Preparation of Diverse Combinatorial Peptidomimetic Bead Libraries , 2004, Molecular Diversity.

[10]  A. Jaśkiewicz,et al.  Inhibition of bovine α-chymotrypsin by cyclic trypsin inhibitor SFTI-1 isolated from sunflower seeds and its two acyclic analogues , 2004, Letters in Peptide Science.

[11]  Robert M Cooke,et al.  A conserved cis peptide bond is necessary for the activity of Bowman-Birk inhibitor protein. , 2002, Biochemistry.

[12]  C. Soto,et al.  Converting a peptide into a drug: strategies to improve stability and bioavailability. , 2002, Current medicinal chemistry.

[13]  A. Jaśkiewicz,et al.  Chemical synthesis and kinetic study of the smallest naturally occurring trypsin inhibitor SFTI-1 isolated from sunflower seeds and its analogues. , 2002, Biochemical and biophysical research communications.

[14]  R. Leatherbarrow,et al.  Peptide mimics of the Bowman-Birk inhibitor reactive site loop. , 2002, Biopolymers.

[15]  M. Selsted,et al.  Identification of Constituents of Human Neutrophil Azurophil Granules That Mediate Fungistasis againstHistoplasma capsulatum , 2000, Infection and Immunity.

[16]  C. Craik,et al.  Cathepsin G Activates Protease-activated Receptor-4 in Human Platelets* , 2000, The Journal of Biological Chemistry.

[17]  S Luckett,et al.  High-resolution structure of a potent, cyclic proteinase inhibitor from sunflower seeds. , 1999, Journal of molecular biology.

[18]  J Otlewski,et al.  Interscaffolding additivity: binding of P1 variants of bovine pancreatic trypsin inhibitor to four serine proteases. , 1999, Journal of molecular biology.

[19]  R. Leatherbarrow,et al.  The role of the P2' position of Bowman-Birk proteinase inhibitor in the inhibition of trypsin. Studies on P2' variation in cyclic peptides encompassing the reactive site loop. , 1999, Biochimica et biophysica acta.

[20]  C. Owen,et al.  Angiotensin II generation at the cell surface of activated neutrophils: novel cathepsin G-mediated catalytic activity that is resistant to inhibition. , 1998, Journal of immunology.

[21]  A. Jaśkiewicz,et al.  Distance between the basic group of the amino acid residue's side chain in position P1 of trypsin inhibitor CMTI-III and Asp189 in the substrate pocket of trypsin has an essential influence on the inhibitory activity. , 1997, Biochemical and Biophysical Research Communications - BBRC.

[22]  J. Karn,et al.  An inhibitor of the Tat/TAR RNA interaction that effectively suppresses HIV-1 replication. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[23]  S. Anderson,et al.  Binding of amino acid side-chains to S1 cavities of serine proteinases. , 1997, Journal of molecular biology.

[24]  W. Shafer,et al.  Bactericidal activity of a synthetic peptide (CG 117-136) of human lysosomal cathepsin G is dependent on arginine content , 1996, Infection and immunity.

[25]  G. Caughey.  Serine proteinases of mast cell and leukocyte granules. A league of their own. , 1994, American journal of respiratory and critical care medicine.

[26]  B. Chait,et al.  Two‐step selective formation of three disulfide bridges in the synthesis of the C‐terminal epidermal growth factor‐like domain in human blood coagulation factor IX , 1994, Protein science : a publication of the Protein Society.

[27]  Stephen B. H. Kent,et al.  Efficient method for the preparation of peptoids [oligo(N-substituted glycines)] by submonomer solid-phase synthesis , 1992 .

[28]  N. Solé,et al.  Optimization of solid-phase synthesis of [Ala8]-dynorphin A , 1992 .

[29]  P. Turkington.  Cathepsin G, a regulator of human vitamin K, dependent clotting factors and inhibitors. , 1992, Thrombosis research.

[30]  M. Laskowski,et al.  Thermodynamics and kinetics of single residue replacements in avian ovomucoid third domains: effect on inhibitor interactions with serine proteinases. , 1982, Biochemistry.