A new diketopiperazine-like inhibitor of bone morphogenetic protein-induced osteoblastic differentiation produced by marine-derived Aspergillus sp. BFM-0085

[1]  Bin Yang,et al.  Structurally diverse diketopiperazine alkaloids from the marine-derived fungus Aspergillus versicolor SCSIO 41016 , 2019, Organic Chemistry Frontiers.

[2]  Y. Liu,et al.  Protuboxepin C and protuboxepin D from the sponge-derived fungus Aspergillus sp SCSIO XWS02F40 , 2018, Natural product research.

[3]  Y. Nakachi,et al.  Recent Topics in Fibrodysplasia Ossificans Progressiva , 2018, Endocrinology and metabolism.

[4]  S. Ohte,et al.  Scopranones with Two Atypical Scooplike Moieties Produced by Streptomyces sp. BYK-11038. , 2017, Organic letters.

[5]  K. Kawakami,et al.  Activin-A enhances mTOR signaling to promote aberrant chondrogenesis in fibrodysplasia ossificans progressiva. , 2017, The Journal of clinical investigation.

[6]  A. Economides,et al.  Palovarotene Inhibits Heterotopic Ossification and Maintains Limb Mobility and Growth in Mice With the Human ACVR1R206H Fibrodysplasia Ossificans Progressiva (FOP) Mutation , 2016, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[7]  Ke-Chun Liu,et al.  Alkaloids with Cardiovascular Effects from the Marine-Derived Fungus Penicillium expansum Y32 , 2015, Marine drugs.

[8]  Lily Huang,et al.  ACVR1R206H receptor mutation causes fibrodysplasia ossificans progressiva by imparting responsiveness to activin A , 2015, Science Translational Medicine.

[9]  S. Ohte,et al.  5-Prenyltryptophol, a new inhibitor of bone morphogenetic protein-induced alkaline phosphatase expression in myoblasts, produced by Streptomyces colinus subsp. albescens HEK608 , 2014, The Journal of Antibiotics.

[10]  F. Kaplan,et al.  Fibrodysplasia ossificans progressiva: mechanisms and models of skeletal metamorphosis , 2012, Disease Models & Mechanisms.

[11]  Y. Mishina,et al.  Corrigendum: Potent inhibition of heterotopic ossification by nuclear retinoic acid receptor–γ agonists , 2012, Nature Medicine.

[12]  S. Ohte,et al.  Trichocyalides A and B, new inhibitors of alkaline phosphatase activity in bone morphogenetic protein-stimulated myoblasts, produced by Trichoderma sp. FKI-5513 , 2012, The Journal of Antibiotics.

[13]  Yukihiro Asami,et al.  Protuboxepin A, a marine fungal metabolite, inducing metaphase arrest and chromosomal misalignment in tumor cells. , 2012, Bioorganic & medicinal chemistry.

[14]  S. Ohte,et al.  Fungal pyrrolidine-containing metabolites inhibit alkaline phosphatase activity in bone morphogenetic protein-stimulated myoblastoma cells , 2012 .

[15]  Yukihiro Asami,et al.  Protuboxepins A and B and protubonines A and B from the marine-derived fungus Aspergillus sp. SF-5044. , 2011, Journal of natural products.

[16]  Masahiro Iwamoto,et al.  Potent Inhibition of Heterotopic Ossification by Nuclear Retinoic Acid Receptor γ Agonists , 2011, Nature Medicine.

[17]  Y. Okazaki,et al.  Constitutively activated ALK2 and increased SMAD1/5 cooperatively induce bone morphogenetic protein signaling in fibrodysplasia ossificans progressiva. , 2009, The Journal of biological chemistry.

[18]  Tomokazu Fukuda,et al.  BMP type I receptor inhibition reduces heterotopic ossification , 2008, Nature Medicine.

[19]  In Ho Choi,et al.  A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva , 2006, Nature Genetics.

[20]  T. Mosmann.  Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. , 1983, Journal of immunological methods.