An integrated microfluidic device for large-scale in situ click chemistry screening.
暂无分享,去创建一个
Yanju Wang | Michael E Phelps | Wei-Yu Lin | Nangang Zhang | Kan Liu | Hsian-Rong Tseng | Matthias Selke | Xing-Zhong Zhao | H. Tseng | M. Phelps | Xingzhong Zhao | H. Kolb | Nangang Zhang | Kan Liu | C. Shen | K. Faull | Yanju Wang | Wei-Yu Lin | M. Selke | Hartmuth C Kolb | Rachel J Lin | Kym F Faull | Clifton K F Shen | Wei‐Yu Lin
[1] R. Ismagilov,et al. Effects of viscosity on droplet formation and mixing in microfluidic channels , 2004 .
[2] William Lindstrom,et al. Inhibitors of HIV-1 protease by using in situ click chemistry. , 2006, Angewandte Chemie.
[3] Paul Watts,et al. The application of micro reactors for organic synthesis. , 2005, Chemical Society reviews.
[4] Olof Ramström,et al. Drug discovery by dynamic combinatorial libraries , 2002, Nature Reviews Drug Discovery.
[5] Mahesh Uttamchandani,et al. Rapid assembly and in situ screening of bidentate inhibitors of protein tyrosine phosphatases. , 2006, Organic letters.
[6] J. V. van Maarseveen,et al. Click chemistry as a route to cyclic tetrapeptide analogues: synthesis of cyclo-[Pro-Val-psi(triazole)-Pro-Tyr]. , 2006, Organic letters.
[7] H. Löwe,et al. Chemistry in microstructured reactors. , 2004, Angewandte Chemie.
[8] Bo Huang,et al. Counting Low-Copy Number Proteins in a Single Cell , 2007, Science.
[9] Peter H Seeberger,et al. Microreactors as tools for synthetic chemists-the chemists' round-bottomed flask of the 21st century? , 2006, Chemistry.
[10] S. Quake,et al. Multistep Synthesis of a Radiolabeled Imaging Probe Using Integrated Microfluidics , 2005, Science.
[11] S. Quake,et al. Monolithic microfabricated valves and pumps by multilayer soft lithography. , 2000, Science.
[12] Jeremy L. Steinbacher,et al. Greener approaches to organic synthesis using microreactor technology. , 2007, Chemical reviews.
[13] Sherry L. Niessen,et al. Proteomic profiling of metalloprotease activities with cocktails of active-site probes , 2006, Nature chemical biology.
[14] Zoran Radić,et al. In situ click chemistry: enzyme inhibitors made to their own specifications. , 2004, Journal of the American Chemical Society.
[15] Zoran Radić,et al. In situ selection of lead compounds by click chemistry: target-guided optimization of acetylcholinesterase inhibitors. , 2005, Journal of the American Chemical Society.
[16] R. Stroud,et al. Site-directed ligand discovery. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[17] T. Wirth,et al. Advanced organic synthesis using microreactor technology. , 2007, Organic & biomolecular chemistry.
[18] G. Whitesides. The origins and the future of microfluidics , 2006, Nature.
[19] Rustem F Ismagilov,et al. Formation of droplets of alternating composition in microfluidic channels and applications to indexing of concentrations in droplet-based assays. , 2004, Analytical chemistry.
[20] C. Seto,et al. A two stage click-based library of protein tyrosine phosphatase inhibitors. , 2007, Bioorganic & medicinal chemistry.
[21] Chi-Huey Wong,et al. In situ click chemistry: enzyme-generated inhibitors of carbonic anhydrase II. , 2004, Angewandte Chemie.
[22] A. deMello. Control and detection of chemical reactions in microfluidic systems , 2006, Nature.
[23] Nasreen S Jessani,et al. Activity-based probes for the proteomic profiling of metalloproteases. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[24] J. Kobayashi,et al. Multiphase organic synthesis in microchannel reactors. , 2006, Chemistry, an Asian journal.
[25] G. Whitesides,et al. Formation of droplets and bubbles in a microfluidic T-junction-scaling and mechanism of break-up. , 2006, Lab on a chip.
[26] Hong-Gang Wang,et al. Bcl-XL-templated assembly of its own protein-protein interaction modulator from fragments decorated with thio acids and sulfonyl azides. , 2008, Journal of the American Chemical Society.
[27] Michael E Phelps,et al. Integrated microfluidics for parallel screening of an in situ click chemistry library. , 2006, Angewandte Chemie.
[28] Jun-ichi Yoshida,et al. Flash chemistry: fast chemical synthesis by using microreactors. , 2008, Chemistry.
[29] A V Eliseev,et al. Dynamic Combinatorial Chemistry , 2001, Science.
[30] K. Sharpless,et al. A click chemistry approach to tetrazoles by Huisgen 1,3-dipolar cycloaddition: synthesis of 5-sulfonyl tetrazoles from azides and sulfonyl cyanides. , 2002, Angewandte Chemie.
[31] P. Taylor,et al. Click chemistry in situ: acetylcholinesterase as a reaction vessel for the selective assembly of a femtomolar inhibitor from an array of building blocks. , 2002, Angewandte Chemie.
[32] J. Lehn,et al. Virtual combinatorial libraries: dynamic generation of molecular and supramolecular diversity by self-assembly. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[33] Chi‐Huey Wong,et al. A Potent and Highly Selective Inhibitor of Human α-1,3-Fucosyltransferase via Click Chemistry , 2003 .
[34] D. Rideout. Self-assembling cytotoxins. , 1986, Science.