High-yield production of l-serine through a novel identified exporter combined with synthetic pathway in Corynebacterium glutamicum

[1]  Morten H. H. Nørholm,et al.  Industrializing a bacterial strain for L-serine production through translation initiation optimization. , 2019, ACS synthetic biology.

[2]  M. Koffas,et al.  Microbial Production of l-Serine from Renewable Feedstocks. , 2018, Trends in biotechnology.

[3]  V. Wendisch,et al.  Transport and metabolic engineering of the cell factory Corynebacterium glutamicum. , 2018, FEMS microbiology letters.

[4]  B. Eikmanns,et al.  The RamA regulon: complex regulatory interactions in relation to central metabolism in Corynebacterium glutamicum , 2018, Applied Microbiology and Biotechnology.

[5]  Zhenghong Xu,et al.  Integration of ARTP mutagenesis with biosensor-mediated high-throughput screening to improve l-serine yield in Corynebacterium glutamicum , 2018, Applied Microbiology and Biotechnology.

[6]  Ping Zheng,et al.  A Novel Corynebacterium glutamicum l-Glutamate Exporter , 2018, Applied and Environmental Microbiology.

[7]  L. Eggeling Exporters for Production of Amino Acids and Other Small Molecules. , 2016, Advances in biochemical engineering/biotechnology.

[8]  Adam M. Feist,et al.  Increased production of L-serine in Escherichia coli through Adaptive Laboratory Evolution. , 2017, Metabolic engineering.

[9]  Volker F. Wendisch,et al.  Roles of export genes cgmA and lysE for the production of l-arginine and l-citrulline by Corynebacterium glutamicum , 2016, Applied Microbiology and Biotechnology.

[10]  Alex Toftgaard Nielsen,et al.  Engineering of high yield production of L‐serine in Escherichia coli , 2016, Biotechnology and bioengineering.

[11]  Brian F. Pfleger,et al.  Efflux systems in bacteria and their metabolic engineering applications , 2015, Applied Microbiology and Biotechnology.

[12]  Tingyi Wen,et al.  YjeH Is a Novel Exporter of l-Methionine and Branched-Chain Amino Acids in Escherichia coli , 2015, Applied and Environmental Microbiology.

[13]  E. Isogai,et al.  Characterization of the l-alanine exporter AlaE of Escherichia coli and its potential role in protecting cells from a toxic-level accumulation of l-alanine and its derivatives , 2015, MicrobiologyOpen.

[14]  E. Schneider,et al.  Structural basis for substrate specificity of an amino acid ABC transporter , 2015, Proceedings of the National Academy of Sciences.

[15]  Zhenghong Xu,et al.  l-Serine overproduction with minimization of by-product synthesis by engineered Corynebacterium glutamicum , 2014, Applied Microbiology and Biotechnology.

[16]  Zhenghong Xu,et al.  Characterization, modification, and overexpression of 3-phosphoglycerate dehydrogenase in Corynebacterium glutamicum for enhancing l-serine production , 2014, Annals of Microbiology.

[17]  Yun Zhang,et al.  Characterization and Molecular Mechanism of AroP as an Aromatic Amino Acid and Histidine Transporter in Corynebacterium glutamicum , 2013, Journal of bacteriology.

[18]  Torsten Schwede,et al.  Protein modeling: what happened to the "protein structure gap"? , 2013, Structure.

[19]  J. Gowrishankar,et al.  Transcriptional Cross-Regulation between Gram-Negative and Gram-Positive Bacteria, Demonstrated Using ArgP-argO of Escherichia coli and LysG-lysE of Corynebacterium glutamicum , 2012, Journal of bacteriology.

[20]  Michael Bott,et al.  A high-throughput approach to identify genomic variants of bacterial metabolite producers at the single-cell level , 2012, Genome Biology.

[21]  J. Keasling,et al.  Engineering microbial biofuel tolerance and export using efflux pumps , 2011, Molecular systems biology.

[22]  Zhi Zhao,et al.  The ncgl1108 (PhePCg) gene encodes a new l-Phe transporter in Corynebacterium glutamicum , 2011, Applied Microbiology and Biotechnology.

[23]  Xiaoyuan Wang,et al.  Construction of a novel promoter-probe vector and its application for screening strong promoter for Brevibacterium flavum metabolic engineering , 2011 .

[24]  Xiaoyuan Wang,et al.  An improved shuttle vector constructed for metabolic engineering research in Corynebacterium glutamicum. , 2010, Plasmid.

[25]  Kay Marin,et al.  Identification of the membrane protein SucE and its role in succinate transport in Corynebacterium glutamicum , 2010, Applied Microbiology and Biotechnology.

[26]  S. Maddocks,et al.  Structure and function of the LysR-type transcriptional regulator (LTTR) family proteins. , 2008, Microbiology.

[27]  Hisao Ito,et al.  Mutations of the Corynebacterium glutamicum NCgl1221 Gene, Encoding a Mechanosensitive Channel Homolog, Induce l-Glutamic Acid Production , 2007, Applied and Environmental Microbiology.

[28]  Michael Stolz,et al.  Reduced Folate Supply as a Key to Enhanced l-Serine Production by Corynebacterium glutamicum , 2006, Applied and Environmental Microbiology.

[29]  H. Sahm,et al.  Metabolic Engineering of Corynebacterium glutamicum for l-Serine Production , 2005, Applied and Environmental Microbiology.

[30]  B. Bathe,et al.  Characterization of Methionine Export in Corynebacterium glutamicum , 2005, Journal of bacteriology.

[31]  J. Gowrishankar,et al.  Evidence for an Arginine Exporter Encoded by yggA (argO) That Is Regulated by the LysR-Type Transcriptional Regulator ArgP in Escherichia coli , 2004, Journal of bacteriology.

[32]  Lothar Eggeling,et al.  New ubiquitous translocators: amino acid export by Corynebacterium glutamicum and Escherichia coli , 2003, Archives of Microbiology.

[33]  Hilde van der Togt,et al.  Publisher's Note , 2003, J. Netw. Comput. Appl..

[34]  M. Saier,et al.  Export of l-Isoleucine from Corynebacterium glutamicum: a Two-Gene-Encoded Member of a New Translocator Family , 2002, Journal of bacteriology.

[35]  H. Sahm,et al.  Identification of glyA (Encoding Serine Hydroxymethyltransferase) and Its Use Together with the Exporter ThrE To Increase l-Threonine Accumulation by Corynebacterium glutamicum , 2002, Applied and Environmental Microbiology.

[36]  H. Sahm,et al.  l-Threonine Export: Use of Peptides To Identify a New Translocator from Corynebacterium glutamicum , 2001, Journal of bacteriology.

[37]  A. Bellmann,et al.  Expression control and specificity of the basic amino acid exporter LysE of Corynebacterium glutamicum. , 2001, Microbiology.

[38]  A. Böck,et al.  Identification of a major facilitator protein from Escherichia coli involved in efflux of metabolites of the cysteine pathway , 2000, Molecular microbiology.

[39]  M. Vrljic,et al.  A new type of transporter with a new type of cellular function: l‐lysine export from Corynebacterium glutamicum , 1996, Molecular microbiology.

[40]  J. Kalinowski,et al.  Small mobilizable multi-purpose cloning vectors derived from the Escherichia coli plasmids pK18 and pK19: selection of defined deletions in the chromosome of Corynebacterium glutamicum. , 1994, Gene.

[41]  H. Sahm,et al.  Isoleucine synthesis in Corynebacterium glutamicum: molecular analysis of the ilvB-ilvN-ilvC operon , 1993, Journal of bacteriology.