α1‐RECEPTOR OR ADENOSINE A1‐RECEPTOR DEPENDENT PATHWAY ALONE IS NOT SUFFICIENT BUT SUMMATION OF THESE PATHWAYS IS REQUIRED TO ACHIEVE AN ISCHAEMIC PRECONDITIONING EFFECT IN RABBITS

1. It is reported that α1‐receptors and adenosine A1‐receptors are involved in the ischaemic preconditioning (PC) effect on infarct size (IS). However, it is still unclear to what extent α1‐receptors and adenosine A1‐receptors contribute to the mechanism of PC. Therefore, we investigated the extent of the contribution of α1‐receptors and adenosine A1 receptors to the PC effect on IS and examined the relationship between these receptors and protein kinase C.

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