Sunscreens with Titanium Dioxide (TiO2) Nano-Particles: A Societal Experiment

The risks of novel technologies, such as nano(bio)technology cannot be fully assessed due to the existing uncertainties surrounding their introduction into society. Consequently, the introduction of innovative technologies can be conceptualised as a societal experiment, which is a helpful approach to evaluate moral acceptability. This approach is illustrated with the marketing of sunscreens containing nano-sized titanium dioxide (TiO2) particles. We argue that the marketing of this TiO2 nanomaterial in UV protective cosmetics is ethically undesirable, since it violates four reasonable moral conditions for societal experimentation (absence of alternatives, controllability, limited informed consent, and continuing evaluation). To remedy the current way nano-sized TiO2 containing sunscreens are utilised, we suggest five complementing actions (closing the gap, setup monitoring tools, continuing review, designing for safety, and regulative improvements) so that its marketing can become more acceptable.

[1]  A. Fairbrother,et al.  Are environmental regulations keeping up with innovation? A case study of the nanotechnology industry. , 2009, Ecotoxicology and environmental safety.

[2]  Xiaobo Chen,et al.  Titanium dioxide nanomaterials: synthesis, properties, modifications, and applications. , 2007, Chemical reviews.

[3]  O. Renn,et al.  Nanotechnology and the need for risk governance , 2006, Emerging Technologies: Ethics, Law and Governance.

[4]  Lucas Reijnders,et al.  Cleaner nanotechnology and hazard reduction of manufactured nanoparticles , 2006 .

[5]  M. Roberts,et al.  Grey Goo on the Skin? Nanotechnology, Cosmetic and Sunscreen Safety , 2007, Critical reviews in toxicology.

[6]  I. A. Siddiquey,et al.  The effects of organic surface treatment by methacryloxypropyltrimethoxysilane on the photostability of TiO2 , 2007 .

[7]  Wolfgang Krohn,et al.  Society as a laboratory: the social risks of experimental research , 1994 .

[8]  K. Wittmaack.  In Search of the Most Relevant Parameter for Quantifying Lung Inflammatory Response to Nanoparticle Exposure: Particle Number, Surface Area, or What? , 2006, Environmental health perspectives.

[9]  Güunter Oberdürster.  Toxicology of ultrafine particles: in vivo studies , 2000, Philosophical Transactions of the Royal Society of London. Series A: Mathematical, Physical and Engineering Sciences.

[10]  R. Falkner,et al.  Securing the Promise of Nanotechnologies , 2009 .

[11]  Nancy D Denslow,et al.  Comparison of molecular and histological changes in zebrafish gills exposed to metallic nanoparticles. , 2009, Toxicological sciences : an official journal of the Society of Toxicology.

[12]  Hari Singh Nalwa,et al.  Nanotechnology and health safety--toxicity and risk assessments of nanostructured materials on human health. , 2007, Journal of nanoscience and nanotechnology.

[13]  David M. Berube,et al.  Rhetorical gamesmanship in the nano debates over sunscreens and nanoparticles , 2008 .

[14]  Bin Zhao,et al.  Ultrafine anatase TiO2 nanoparticles produced in premixed ethylene stagnation flame at 1 atm , 2005 .

[15]  J. Everitt,et al.  Pulmonary responses of mice, rats, and hamsters to subchronic inhalation of ultrafine titanium dioxide particles. , 2004, Toxicological sciences : an official journal of the Society of Toxicology.

[16]  Vincent Castranova,et al.  Iron oxide nanoparticles induce human microvascular endothelial cell permeability through reactive oxygen species production and microtubule remodeling , 2009, Particle and Fibre Toxicology.

[17]  M. Plummer,et al.  International agency for research on cancer. , 2020, Archives of pathology.

[18]  Günter Oberdörster,et al.  Toxicology of ultrafine particles: in vivo studies , 2000 .

[19]  Wei Li,et al.  Time-dependent translocation and potential impairment on central nervous system by intranasally instilled TiO(2) nanoparticles. , 2008, Toxicology.

[20]  M. Anpo.  Preparation, Characterization, and Reactivities of Highly Functional Titanium Oxide-Based Photocatalysts Able to Operate under UV—Visible Light Irradiation: Approaches in Realizing High Efficiency in the Use of Visible Light , 2004 .

[21]  Jukka Ahtiainen,et al.  Scientific Committee on Emerging and Newly Identified Health Risks SCENIHR Risk Assessment of Products of Nanotechnologies , 2009 .

[22]  Mihail C. Roco,et al.  Nanotechnology Risk Governance , 2008 .

[23]  O A Sadik,et al.  Sensors as tools for quantitation, nanotoxicity and nanomonitoring assessment of engineered nanomaterials. , 2009, Journal of environmental monitoring : JEM.

[24]  M. Marinovich,et al.  Risk Assessment of Products of Nanotechnologies , 2009 .

[25]  Amos Branch,et al.  The interaction of modern sunscreen formulations with surface coatings , 2008 .

[26]  A. Salinaro,et al.  Beneficial effects of photo-inactive titanium dioxide specimens on plasmid DNA, human cells and yeast cells exposed to UVA/UVB simulated sunlight , 2006 .

[27]  Vincent Castranova,et al.  Surface area of particle administered versus mass in determining the pulmonary toxicity of ultrafine and fine carbon black: comparison to ultrafine titanium dioxide , 2009, Particle and Fibre Toxicology.

[28]  Luke J Mortensen,et al.  In vivo skin penetration of quantum dot nanoparticles in the murine model: the effect of UVR. , 2008, Nano letters.