Regional cerebral blood flow in apoplexy due to occlusion of the middle cerebral artery

THE XENON 133 INJECTION METHOD allows simultaneous measurement of the blood flow in many areas of the brain.l.2 It has been used for determination of the regional cerebral blood flow in several small series of patients with cerebrovascular diseases of various types.3-7a The regional flow responses of the braip to changes of arterial blood pressure and arterial pC0, have also been studied, and focal loss of autoregulation and of pC0,-induced vasodilatation in cases of cerebral apoplexy have been reported."6y7a In the present study, a group of apoplectics with a single pathogenesis, i.e., with acute occlusion of the middle cerebral artery, has been studied with the aim of collecting information on the regional cerebral blood flow (rCBF) and its regulation in a well-defined type of apoplexy. The results obtained in apoplexy without occlusion of a major cerebral artery and in transient ischemic attacks will be reported in subsequent paper^.^.^

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