Barrett's esophagus: A prevalent, occult complication of gastroesophageal reflux disease

Abstract A prospective study of patients with symptoms of gastroesophageal reflux was undertaken to determine the prevalence of Barrett's esophagus and reevaluate the diagnostic approach necessary to detect this complication. Endoscopy with mucosal biopsy was performed in 97 subjects. Twelve (12.4%) were found to have Barrett's esophagus. The sensitivity and specificity of the endoscopic and radiologic examinations for Barrett's esophagus were prospectively evaluated. Endoscopy (92%) was significantly more sensitive than radiology (24%) in detecting Barrett's esophagus (p

[1]  F. Ellis,et al.  Adenocarcinoma complicating columnar epithelium-lined (Barrett's) esophagus. , 1978, American journal of clinical pathology.

[2]  E. Burbige,et al.  Characteristics of the columnar-cell lined (Barrett's) esophagus. , 1979, Gastrointestinal endoscopy.

[3]  M. Savary,et al.  Columnar-lined lower esophagus: an acquired lesion with malignant predisposition. Report on 140 cases of Barrett's esophagus with 12 adenocarcinomas. , 1975, The Journal of thoracic and cardiovascular surgery.

[4]  J. C. Mangla.  Barrett's esophagus: an old entity rediscovered. , 1981, Journal of clinical gastroenterology.

[5]  R. Goyal,et al.  The histologic spectrum of Barrett's esophagus. , 1976, The New England journal of medicine.

[6]  P. Greenland,et al.  Selection and interpretation of diagnostic tests and procedures. Principles and applications. , 1981, Annals of internal medicine.

[7]  W. Schenk,et al.  Carnitine levels in severe infection and starvation: a possible key to the prolonged catabolic state. , 1970, Surgery.

[8]  J. Richter,et al.  Gastroesophageal Reflux: Pathogenesis, Diagnosis, and Therapy , 1982 .

[9]  R. Fontana,et al.  Adenocarcinoma in the columnar epithelial lined lower (Barrett) oesophagus , 1973 .

[10]  J. J. Thompson,et al.  Barrett esophagus: reticular pattern of the mucosa. , 1983, Radiology.

[11]  L. Johnson,et al.  Barrett's esophagus: a review. , 1983, The American journal of medicine.

[12]  M. Goldman,et al.  Barrett syndrome. Case report with discussion about concepts of pathogenesis. , 1960, Gastroenterology.

[13]  Ellis Fh,et al.  Barrett's esophagus: congenital or acquired? An experimental study of esophageal mucosal regeneration in the dog. , 1970 .

[14]  J. Borrie,et al.  Columnar cell-lined esophagus: assessment of etiology and treatment. A 22 year experience. , 1976, The Journal of thoracic and cardiovascular surgery.

[15]  R. Adler.  The lower esophagus lined by columnar epithelium. Its association with hiatal hernia, ulcer, stricture, and tumor. , 1963 .

[16]  M. Bains,et al.  Adenocarcinoma in Barrett's esophagus. , 1983, The Journal of thoracic and cardiovascular surgery.

[17]  C. Pope,et al.  Histological consequences of gastroesophageal reflux in man. , 1970, Gastroenterology.

[18]  D. Skinner,et al.  Barrett's esophagus. Functional assessment, proposed pathogenesis, and surgical therapy. , 1983, Archives of surgery.

[19]  N. Barrett.  Chronic peptic ulcerz of the œophagus and ‘œsophagitis’ , 1950 .

[20]  D. Powell,et al.  Barrett's esophagus: clinical, endoscopic, histologic, manometric, and electrical potential difference characteristics. , 1984, Gastroenterology.

[21]  D. Skinner,et al.  Barrett's Esophagus: Comparison of Benign and Malignant Cases , 1983, Annals of surgery.

[22]  R. C. Duncan,et al.  Introductory Biostatistics for the Health Sciences. , 1984 .