A Comparison of the Harvard 700 Diet (Modified) with the HWC Diet (Modified) for Inducing Occlusal Caries in Resistant and Susceptible Rats

The development of caries-resistant and caries-susceptible rats by Hunt and Hoppertl-6 was facilitated by the Hoppert-Webber-Canniff (HWC) coarse-particle diet. 8 The difference between the two lines was still evident when certain high-sucrose diets were used.9"10 Shaw reported that a high-sucrose ration caused greater destruction of the teeth than did the HWC diet." This investigation was designed to assess the cariogenicity of this diet and to determine whether the difference between the two strains persisted. Lactobacilli and streptococci were quantitatively determined, in order to ascertain the relationship between diet, caries, and these microorganisms.

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