Foci of increased T2 signal intensity on brain MR scans of healthy elderly subjects.

Foci of increased T2 signal intensity were found on brain MR scans in 16 (59%) of 27 healthy elderly volunteer subjects, ages 63 to 86 years old. These foci were not related to cognitive function or cerebrovascular risk factors; instead, they were highly correlated to age, being present in 11 of 11 subjects aged 75 years and over.

[1]  G. Román,et al.  Senile dementia of the Binswanger type. A vascular form of dementia in the elderly. , 1987, JAMA.

[2]  D. O'leary,et al.  White matter lucencies on computed tomography, subacute arteriosclerotic encephalopathy (Binswanger's disease), and blood pressure. , 1987, Stroke.

[3]  M. Gado,et al.  Periventricular white matter lucencies in senile dementia of the Alzheimer type and in normal aging , 1987, Neurology.

[4]  G. Sarpel,et al.  Magnetic resonance imaging of periventricular hyperintensity in a Veterans Administration hospital population. , 1987, Archives of neurology.

[5]  P. Ambrosetto.  CT changes in dementing diseases. , 1987, AJNR. American journal of neuroradiology.

[6]  L A Hayman,et al.  White-matter lesions in MR imaging of clinically healthy brains of elderly subjects: possible pathologic basis. , 1987, Radiology.

[7]  M. Modic,et al.  Magnetic resonance imaging in vascular dementia , 1987, Neurology.

[8]  J. Wade,et al.  Vascular risk factors and leuko-araiosis. , 1987, Archives of neurology.

[9]  V. Hachinski,et al.  Cognitive and neurologic findings in subjects with diffuse white matter lucencies on computed tomographic scan (leuko-araiosis). , 1987, Archives of neurology.

[10]  V. Hachinski,et al.  Cognitive and neurologic findings in demented patients with diffuse white matter lucencies on computed tomographic scan (leuko-araiosis). , 1987, Archives of neurology.

[11]  F. Huppert,et al.  CAMDEX: A Standardised Instrument for the Diagnosis of Mental Disorder in the Elderly with Special Reference to the Early Detection of Dementia , 1986, British Journal of Psychiatry.

[12]  R F Spetzler,et al.  Incidental subcortical lesions identified on magnetic resonance imaging in the elderly. I. Correlation with age and cerebrovascular risk factors. , 1986, Stroke.

[13]  B. Reisberg,et al.  Periventricular lucencies in the CT scans of aged and demented patients , 1986, Biological Psychiatry.

[14]  L. Weisberg,et al.  MRI periventricular lesions in adults , 1986, Neurology.

[15]  M. Leon,et al.  Leukoencephalopathy in normal and pathologic aging: 2. MRI of brain lucencies. , 1986, AJNR. American journal of neuroradiology.

[16]  L A Saint-Louis,et al.  Periventricular hyperintensity as seen by magnetic resonance: prevalence and significance. , 1986, AJR. American journal of roentgenology.

[17]  A. Reeves,et al.  Neurologic signs in senescence. , 1985, Archives of neurology.

[18]  M Brant-Zawadzki,et al.  MR imaging of the aging brain: patchy white-matter lesions and dementia. , 1985, AJNR. American journal of neuroradiology.

[19]  T. Erkinjuntti,et al.  Cerebral NMR and CT Imaging in Dementia , 1984, Journal of computer assisted tomography.

[20]  W. Bradley.  Patchy, periventricular white matter lesions in the elderly : common observation during NMR imaging , 1984 .

[21]  T. Jernigan,et al.  White Matter Changes in Cerebral Computed Tomography Related to Aging , 1982, Journal of computer assisted tomography.

[22]  H. Fukasawa,et al.  Diffuse white-matter disease in the geriatric population. A clinical, neuropathological, and CT study. , 1981, Radiology.

[23]  L. Jacobs,et al.  Three primitive reflexes in normal adults , 1980, Neurology.

[24]  S. Folstein,et al.  "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. , 1975, Journal of psychiatric research.