[Space medicine and life sciences in space].

The examination of pathophysiological disturbances and the process of adaptation in man during space flight is not for optimizing of the biological systems during the training of cosmonauts and astronauts for their stay in space only. These results are also important for medical application on patients. In real microgravity disturbances of motor performances, coordination of movements, accuracy of movements, muscle function as well as structural changes in muscles is found in real microgravity. Spinal reflexes and the control of vestibular system on eye movements are also afflicted. Higher brain functions, especially associative reactions, critical abilities, memory, as well as high brain function like space orientation, body scheme control, geometric and arithmetic analysis and its reproduction, at last speech production, writing and reading are decreased. Vegetative disorders, bone decalcification, primary muscular atrophy occur as well as changes in sleep--wake regulation and diminishing of vigility. Disturbances of blood and body fluid circulation and biologic radiation damage are further effects of man space flight. Several problems of space adaptation can be studied with the methods of the simulated microgravity using the dry water immersion, examination and the bed rest model in special laboratories. The routine medicine is learning from the scientific results of the research in real and simulated microgravity.