Studies conducted in Zagreb reported a short-term relation between weekly air pollutant concentrations and morbidity and mortality. Air pollution in Zagreb is generally below the limit, and usually within the recommended values of the World Health Organization. Daily variations in general mortality were related with daily variations in air pollution for the period 1995-1997. Poisson regression models were used, controlling for possible confounders, seasonallity, trend, and autoregressive patterns. NO2 was related to general mortality. The best fit was achieved for the four day average concentrations (relative risk /RR/ for 50 ľg/m3 was 1.114 with 95% confidence limits 1.029-1.204). Black smoke and SO2 were not related to general mortality.