The Role of the Mauthner Cell in Fast-Starts Involving Escape in Teleost Fishes

The commonly observed “tailflip” startle response is one of the most characteristic behavior patterns of bony and cartilagenous fishes and amphibians. In the most familiar example, the behavior pattern is readily elicited in fish following a tap on the side of their aquarium. However, data from behavioral studies show that the response is an effective escape movement that enables the animal to avoid sudden attacks by predators. An example of this is shown in Figure 1 in which a small cyprinid fish uses a common startle response movement pattern to avoid a strike by a piscivorous snake.

[1]  E. Aljure,et al.  Postsynaptic depression of Mauthner cell-mediated startle reflex, a possible contributor to habituation , 1980, Brain Research.

[2]  D. Faber,et al.  A Neuronal Inhibition Mediated Electrically , 1973, Science.

[3]  D. Faber,et al.  Inputs from the posterior lateral line nerves upon the goldfish Mauthner cell. I. Properties and synaptic localization of the excitatory component , 1975, Brain Research.

[4]  Paul W. Webb,et al.  Fast-Start Resistance of Trout , 1982 .

[5]  Edward Koenig,et al.  Mauthner axon diameter and impulse conduction velocity decrease with growth of goldfish , 1981, Neuroscience Letters.

[6]  J. T. Hackett,et al.  Functional properties of afferents which synapse on the Mauthner neuron in the amphibian tadpole , 1979, Brain Research.

[7]  W. K. Metcalfe,et al.  Noninvasive recording of the Mauthner neurone action potential in larval zebrafish. , 1982, The Journal of experimental biology.

[8]  C. Kimmel,et al.  Functional development in the Mauthner cell system of embryos and larvae of the zebra fish. , 1977, Journal of neurobiology.

[9]  D. Faber,et al.  Transmission at a central inhibitory synapse. I. Magnitude of unitary postsynaptic conductance change and kinetics of channel activation. , 1982, Journal of neurophysiology.

[10]  Y. Nakajima Fine structure of the synaptic endings on the Mauthner cell of the goldfish , 1974, The Journal of comparative neurology.

[11]  A. Huxley,et al.  The activation and distribution of GABA and L‐glutamate receptors on goldfish Mauthner neurones: an analysis of dendritic remote inhibition , 1968, The Journal of physiology.

[12]  D. Faber,et al.  Properties and distribution of anterior VIIIth nerve excitatory inputs to the goldfish Mauthner cell , 1979, Brain Research.

[13]  J. T. Hackett,et al.  Does the Mauthner cell conform to the criteria of the command neuron concept? , 1981, Brain Research.

[14]  G. W. Bartelmez Mauthner's cell and the nucleus motorius tegmenti , 1915 .

[15]  D. Faber,et al.  An identifiable class of statoacoustic interneurons with bilateral projections in the goldfish medulla , 1980, Neuroscience.

[16]  D. Hoss,et al.  Startle Response in Herring: The Effect of Sound Stimulus Frequency, Size of Fish and Selective Interference With The Acoustico-Lateralis System , 1981, Journal of the Marine Biological Association of the United Kingdom.

[17]  J. T. Hackett,et al.  The anuran mauthner cell and its synaptic bed , 1980, Neuroscience.

[18]  B. Partridge Lateral Line Function and the Internal Dynamics of Fish Schools , 1981 .

[19]  C. Kimmel,et al.  The development and behavioral characteristics of the startle response in the zebra fish. , 1974, Developmental psychobiology.

[20]  D. Faber,et al.  Myelinated central vertebrate axon lacks voltage-sensitive potassium conductance. , 1981, Science.

[21]  C. Sandri,et al.  The structural correlate of saltatory conduction along the mauthner axon in the tench (Tinea tinea L.): Identification of nodal equivalents at the axon collaterals , 1982, The Journal of comparative neurology.

[22]  M. Celio,et al.  Ultrastructure of the Mauthner axon collateral and its synapses in the goldfish spinal cord , 1979, Journal of neurocytology.

[23]  H Korn,et al.  Electrical inhibition of Purkinje cells in the cerebellum of the rat. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[24]  K. R. Weiss,et al.  The command neuron concept , 1978, Behavioral and Brain Sciences.

[25]  Robert C. Eaton,et al.  An electronic cine camera system for the automatic collection and analysis of high-speed movement of unrestrained animals , 1983 .

[26]  D. Weihs,et al.  The mechanism of rapid starting of slender fish. , 1973, Biorheology.

[27]  Webb Pw,et al.  The effect of size on the fast-start performance of rainbow trout Salmo cairdneri, and a consideration of piscivorous predator-prey interactions. , 1976 .

[28]  Henri Korn,et al.  Neurobiology of the Mauthner cell , 1978 .

[29]  E. Furshpan,et al.  Two inhibitory mechanisms in the Mauthner neurons of goldfish. , 1963, Journal of neurophysiology.

[30]  G. Lauder,et al.  Prey capture in the chain pickerel, Esox niger: correlations between feeding and locomotor behavior , 1981 .

[31]  D. Faber,et al.  Action-potential propagation and orthodromic impulse initiation in Mauthner axon. , 1982, Journal of neurophysiology.

[32]  Richard R. Fay,et al.  Hearing and Sound Communication in Fishes , 1981, Proceedings in Life Sciences.

[33]  D. Faber,et al.  Dual transmission at morphologically mixed synapses: Evidence from postsynaptic cobalt injections , 1980, Neuroscience.

[34]  Y. Fukami,et al.  EFFECTS OF STRYCHNINE AND PROCAINE ON COLLATERAL INHIBITION OF THE MAUTHNER CELL OF GOLDFISH. , 1964, The Japanese journal of physiology.

[35]  Olav Sand,et al.  The Lateral Line and Sound Reception , 1981 .

[36]  C. Kimmel,et al.  Morphogenesis and synaptogenesis of the zebrafish mauthner neuron , 1981, The Journal of comparative neurology.

[37]  Paul W. Webb,et al.  Fast-start Performance and Body Form in Seven Species of Teleost Fish , 1978 .

[38]  H Korn,et al.  An electrically mediated inhibition in goldfish medulla. , 1975, Journal of neurophysiology.

[39]  Paul W. Webb,et al.  Temperature Effects on Acceleration of Rainbow Trout, Salmo gairdneri , 1978 .

[40]  D. Weihs,et al.  Optimal avoidance and evasion tactics in predator-prey interactions , 1984 .

[41]  T. Furukawa Synaptic interaction at the mauthner cell of goldfish. , 1966, Progress in brain research.

[42]  Lawrence M. Dill,et al.  The escape response of the zebra danio (Brachydanio rerio) I. The stimulus for escape , 1974 .

[43]  Donald M. Wilson Function of Giant Mauthner's Neurons in the Lungfish , 1959, Science.

[44]  W. K. Metcalfe,et al.  Brain neurons which project to the spinal cord in young larvae of the zebrafish , 1982, The Journal of comparative neurology.

[45]  S. Zottoli,et al.  Correlation of the startle reflex and Mauthner cell auditory responses in unrestrained goldfish. , 1977, The Journal of experimental biology.

[46]  J. C. Fentress Simpler networks and behavior , 1976 .

[47]  S. Dijkgraaf THE FUNCTIONING and SIGNIFICANCE OF THE LATERAL‐LINE ORGANS , 1963, Biological reviews of the Cambridge Philosophical Society.

[48]  H. Korn,et al.  Transmission at a central inhibitory synapse. III. Ultrastructure of physiologically identified and stained terminals. , 1982, Journal of neurophysiology.

[49]  D. Faber,et al.  Structural correlates of recurrent collateral interneurons producing both electrical and chemical inhibitions of the Mauthner cell , 1978, Proceedings of the Royal Society of London. Series B. Biological Sciences.

[50]  E. Kandel Cellular basis of behavior: An introduction to behavioral neurobiology. , 1976 .

[51]  R. C. Eaton Is the Mauthner Cell a Vertebrate Command Neuron? A Neuroethological Perspective on an Evolving Concept , 1983 .

[52]  S. Roper,et al.  The membrane effects, and sensitivity to strychnine, of neural inhibition of the Mauthner cell, and its inhibition by glycine and GABA , 1973, The Journal of physiology.

[53]  J. Diamond The Mauthner Cell , 1971 .

[54]  J. Gray,et al.  Sound and Startle Responses in Herring Shoals , 1981, Journal of the Marine Biological Association of the United Kingdom.

[55]  R. Farley,et al.  Mauthner neuron field potential in newly hatched larvae of the zebra fish. , 1975, Journal of neurophysiology.

[56]  H. Korn,et al.  Morphologically distinct classes of inhibitory synapses arise from the same neurons: Ultrastructural identification from crossed vestibular interneurons intracellularly stained with HRP , 1981, The Journal of comparative neurology.

[57]  D. Faber,et al.  Differential properties of orthodromic and antidromic impulse propagation across the Mauthner cell initial segment , 1980, Brain Research.

[58]  A. A. Auerbach,et al.  Chemically Mediated Transmission at a Giant Fiber Synapse in the Central Nervous System of a Vertebrate , 1969, The Journal of general physiology.

[59]  P. Webb Does schooling reduce fast-start response latencies in teleosts? , 1980 .

[60]  R. F. Thompson,et al.  Habituation: a model phenomenon for the study of neuronal substrates of behavior. , 1966, Psychological review.

[61]  R. Fernald Fast body turns in a cichlid fish , 1975, Nature.

[62]  T. Bullock Comparisons of the Electric and Acoustic Senses and their Central Processing , 1981 .

[63]  G. L. Vinyard Variable Kinematics of Sacramento Perch (Archoplites interruptus) Capturing Evasive and Nonevasive Prey , 1982 .

[64]  A. Stefanelli The Mauthnerian Apparatus in the Ichthyopsida; Its Nature and Function and Correlated Problems of Neurohistogenesis , 1951, The Quarterly Review of Biology.

[65]  C. Kimmel,et al.  Reticulospinal and vestibulospinal neurons in the young larva of a teleost fish, Brachydanio rerio. , 1982, Progress in brain research.

[66]  R. Melzack,et al.  "TAIL FLIP RESPONSE" IN GOLDFISH. , 1963, Journal of comparative and physiological psychology.

[67]  Paul W. Webb,et al.  Acceleration Performance of Rainbow Trout Salmo Gairdneri and Green Sunfish Lepomis Cyanellus , 1975 .

[68]  Thomas A. Sebeok,et al.  How Animals Communicate , 1979 .

[69]  S. M. Highstein,et al.  Fatigue and recovery of transmission at the Mauthner fiber-giant fiber synapse of the hatchetfish , 1975, Brain Research.

[70]  D. G. Lawrence,et al.  The functional organization of the motor system in the monkey. II. The effects of lesions of the descending brain-stem pathways. , 1968, Brain : a journal of neurology.

[71]  E. Furshpan,et al.  Intracellular and extracellular responses of the several regions of the Mauthner cell of the goldfish. , 1962, Journal of neurophysiology.

[72]  D L Meyer,et al.  The Mauthner-initiated startle response in teleost fish. , 1977, The Journal of experimental biology.

[73]  P. Webb,et al.  Strike tactics of Esox. , 1980, Canadian journal of zoology.

[74]  D. G. Lawrence,et al.  The functional organization of the motor system in the monkey. I. The effects of bilateral pyramidal lesions. , 1968, Brain : a journal of neurology.

[75]  C. Kimmel Development of synapses on the Mauthner neuron , 1982, Trends in Neurosciences.

[76]  H Korn,et al.  Vertebrate central nervous system: same neurons mediate both electrical and chemical inhibitions. , 1976, Science.

[77]  J. T. Hackett,et al.  Mauthner axon networks mediating supraspinal components of the startle response in the goldfish , 1983, Neuroscience.

[78]  D. Faber,et al.  Inputs from the posterior lateral line nerves upon the goldfish Mauthner cell. II. Evidence that the inhibitory components are mediated by interneurons of the recurrent collateral network , 1975, Brain Research.

[79]  T. Furukawa,et al.  Neurophysiological studies on hearing in goldfish. , 1967, Journal of neurophysiology.

[80]  J. Ward,et al.  The development of behavior in the cichlid fish Etroplus maculatus (Bloch). , 2010, Zeitschrift fur Tierpsychologie.

[81]  E. Furshpan "Electrical Transmission" at an Excitatory Synapse in a Vertebrate Brain , 1964, Science.

[82]  A. A. Auerbach,et al.  A Rectifying Electrotonic Synapse in the Central Nervous System of a Vertebrate , 1969, The Journal of general physiology.

[83]  C. Rovainen Neurobiology of lampreys. , 1979, Physiological reviews.

[84]  J. T. Hackett,et al.  Relay neurons mediate collateral inhibition of the goldfish Mauthner cell , 1983, Brain Research.

[85]  M. K. Rock Functional properties of Mauthner cell in the tadpole Rana catesbeiana. , 1980, Journal of neurophysiology.